Instruction for use: Naclof

Active substance Diclofenac

ATX Code S01BC03 Diclofenac

Pharmacological group

NSAIDs - Derivatives of acetic acid and related compounds

Ophthalmic products

Nosological classification (ICD-10)

H10 Conjunctivitis

Conjunctivitis infectious-inflammatory,Bacterial conjunctivitis, red-eye syndrome, Superficial infection of the eye, Chronic non-infectious conjunctivitis

H10.5 Blepharoconjunctivitis

Chronic Blepharoconjunctivitis, Blepharoconjunctivitis, Staphylococcal blepharoconjunctivitis

H16.2 Keratoconjunctivitis

Chronic allergic keratoconjunctivitis, Bacterial keratoconjunctivitis, Deep forms of adenovirus keratoconjunctivitis, Infectious conjunctivitis and keratoconjunctivitis caused by Chlamydia trachomatis, Acute allergic keratoconjunctivitis, Spring keratoconjunctivitis, Phlyctenular keratoconjunctivitis

H18.3 Changes in corneal envelopes

H25 Star cataract

Age-related cataract, Cataract senile, Acute diarrheal cataract, Cataract

S05 Injury of the eye and orbit

Wounds of the eye penetrating, Non-penetrating wound of the eyeball, Superficial injury of the cornea, Post-traumatic keratopathy, Post-traumatic central retinal dystrophy, Penetrating wound of the cornea, Condition after eye injuries, Condition after eyeball injuries, Penetrating corneal wounds, Injuries to eye tissues, Injuries to the cornea, Injury of anterior part of eye

Z100 * CLASS XXII Surgical practice

Abdominal surgery, adenomectomy, Amputation, Coronary angioplasty, Angioplasty of the carotid arteries, Antiseptic skin treatment for wounds, Antiseptic Hand, Appendectomy, atherectomy, Balloon coronary angioplasty, Vaginal hysterectomy, The coronary bypass, Interventions in the vagina and cervix, Interventions on the bladder, Intervention in the mouth, Restoration and reconstructive surgery, Hand hygiene of medical personnel, Gynecologic surgery, Gynecological intervention, Gynecological surgery, Hypovolemic shock during operations, Disinfection of purulent wounds, Disinfection of wounds edges, Diagnostic intervention, Diagnostic procedures, Cervical Diathermocoagulation, Long-surgery, Replacing the fistula catheters, Infection in orthopedic surgery, Artificial heart valve, cystectomy, Short-term outpatient surgery, Short-term operation, Short surgical procedures, Krikotireotomiya, Blood loss during surgery, Bleeding during surgery and in the postoperative period, Kuldotsentez, laser photocoagulation, laser coagulation, retinal laser coagulation, Laparoscopy, Laparoscopy in Gynecology, CSF fistula, Small gynecological operations, Small surgical procedures, Mastectomy and subsequent plastic, mediastinotomy, Microsurgical operations on the ear, Mukogingivalnye operation, suturing, Minor surgery, neurosurgical operation, Immobilization of the eyeball in ophthalmic surgery, testectomy, pancreatectomy, Perikardektomiya, The period of rehabilitation after surgery, The period of, convalescence after surgery, Percutaneous transluminal coronary angioplasty, Pleural thoracentesis, Pneumonia postoperative and posttraumatic, Preparation for surgical procedures, Preparation for surgery, Preparation of the surgeon's hands before surgery, Preparation of the colon for surgical procedures, Postoperative aspiration pneumonia in neurosurgical and thoracic surgery, Postoperative nausea, Postoperative bleeding, postoperative granuloma, postoperative shock, The early postoperative period, myocardial revascularization, Radiectomy, gastric Resection, bowel resection, uterine Resection, liver Resection, enterectomy, Resection of part of the stomach, Reocclusion of the operated vessel, Bonding tissues during surgical procedures, Removal of sutures, Condition after eye surgery, Condition after surgery, Condition after surgery in the nasal cavity, Condition after gastrectomy, Status after resection of the small intestine, Condition after tonsillectomy, Condition after removal of the duodenum, Condition after phlebectomy, Vascular surgery, Splenectomy, Sterilization of surgical instruments, Sterilization of surgical instruments, sternotomy, Dental surgery, Dental intervention in periodontal tissues, strumectomy, Tonsillectomy, Thoracic surgery, total gastrectomy, Transdermal intravascular coronary angioplasty, Transurethral resection, Turbinektomiya, Removal of a tooth, cataract surgery, Removal of cysts, tonsillectomy, Removal of fibroids, Removing the mobile primary teeth, Removing polyps, Removing broken tooth, Removal of the uterus body, Removal of sutures, Urethrotomy, Fistula likvoroprovodyaschih ways, Frontoetmoidogaymorotomiya, Surgical infection, Surgical treatment of chronic limb ulcersm, Surgery, The surgery in the anal area, The surgery on the colon, Surgical practice, The surgical procedure, Surgical interventions, Surgery on the gastrointestinal tract, Surgical procedures on the urinary tract, Surgical procedures on the urinary system, Surgical intervention of the genitourinary system, Surgical procedures on the heart, Surgical manipulation, surgery, Surgery on the veins, Surgical intervention, Vascular surgery, Surgical treatment of thrombosis, cholecystectomy, Partial gastric resection, transabdominal hysterectomy, Percutaneous transluminal coronary angioplasty, Percutaneous transluminal angioplasty, Coronary artery bypass, tooth Extirpation, Extirpation of milk teeth, pulpectomy, pulsative cardiopulmonary bypass, tooth Extraction, teeth Extraction, cataract extraction, Electrocoagulation, endourological intervention, episiotomy, Etmoidotomiya, Complications after tooth extraction

Composition and form of release

1 ml of the eye drops contains 1 mg of diclofenac sodium; in vials of 5 ml.

pharmachologic effect

Pharmacological action - anti-inflammatory, analgesic.

It inhibits cyclooxygenase and inhibits the synthesis of PG.

Pharmacokinetics

Penetrates into the anterior chamber of the eye. Cmax in the cornea and conjunctiva is reached 30 min after instillation.

Clinical Pharmacology

Blocks miosis during operations for cataracts. Prophylactic use reduces the number of cases of cystoid macular edema (or reduces the severity of its course), prevents the development of inflammation and reduces the pain syndrome after the operation of cataract removal and intraocular lens implantation.

Indication

Prevention of myositis, inflammatory processes and cystoid macular edema following operations related to cataract removal and lens implantation, inflammation of non-infectious nature involving the anterior parts of the eye (chronic non-infectious conjunctivitis, etc.), post-traumatic inflammation with penetrating and non-penetrating wounds of the eyeball (as an addition to local anti-infective therapy), pain syndrome when using an excimer laser.

Contraindications

Hypersensitivity (including thiomersal).

pregnancy and lactation

It is permissible, but only in cases of extreme necessity.

Side effects

Transient burning sensation (from mild to moderate), temporary loss of vision clearness immediately after instillation; allergic reactions (itching, redness of the conjunctiva, photosensitivity).

Dosing and Administration

In the conjunctival sac. Before the operation - 1 drop 5 times for 3 hours, after the operation - 1 drop 3 times immediately after the operation, then - 1 drop 3-5 times a day during the time necessary for treatment; other indications - 1 drop 4-5 times a day.

Precautionary measures

Patients who, after application, temporarily lose their clear vision, it is not recommended to drive a car or work with machinery.

storage Conditions

At room temperature.

Keep out of the reach of children.

Shelf life

2.5 years. After opening - 1 month.

Do not use after the expiry date printed on the package.