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Active substance Levonorgestrel + Ethinylestradiol

ATX code G03AA07 Levonorgestrel + Ethinylestradiol

Pharmacological group

Estrogens, gestagens; Their homologues and antagonists

Nosological classification (ICD-10)

N94.6 Dysmenorrhea Unspecified

Pain during menstruation, Functional disorders of the menstrual cycle, Menstrual cramps, Emmeniopathy, Pain during menstruation, Painful menstrual irregularities, algomenorrhea, algomenoreya, Pain smooth muscle spasm, Pain spasm of smooth muscles (renal and biliary colic, intestinal spasms, dysmenorrhea), Pain spasm of smooth muscles of internal organs (kidney and biliary colic, intestinal spasms, dysmenorrhea), Disalgomenoreya, dysmenorrhea, Dysmenorrhea (essential) (Exfoliative), menstrual disorder, menstruation painful, metrorrhagia, Violation of the menstrual cycle, Menstrual irregularities, Prolaktinzavisimoe menstrual disorders, Prolaktinzavisimoe menstrual dysfunction, Pain spasm of smooth muscles of internal organs, Spasmodic dysmenorrhea, Primary disalgomenoreya

Z30 Monitoring contraceptive use

Local Contraception, Contraception oral, Local contraception, Episodic prevention of pregnancy, Hormonal Contraception, Contraception, Prevention of Pregnancy, Prevention of unwanted pregnancy, Contraceptive intrauterine, Contraception in women with androgenization phenomena, Installation and removal of the intrauterine device, Prevention of pregnancy (contraception)

Z30.0 General advice and advice on contraception

Safe sex, Intrauterine device contraception, Contraception, Contraceptive intrauterine, Oral contraception, Oral contraception during lactation and with estrogen contraindications, Postcoital contraception, Prevention of Pregnancy, Prevention of unwanted pregnancy, Emergency Contraception, Episodic prevention of pregnancy, Contraception in adolescents, Prevention of pregnancy (contraception)

Composition and form of release

1 dragee contains levonorgestrel 125 μg and ethinylestradiol 30 μg; In the blister is 21 pcs., In the box 1 blister.

pharmachologic effect

The pharmacological action is estrogen-gestagenic, contraceptive.

Levonorgestrel in combination with ethinyl estradiol blocks the release of releasing factors (luteinizing and follicle-stimulating) of the hypothalamus, inhibits the secretion of the gonadotrophic hormone by the pituitary gland, and thus inhibits ovulation; Increases the viscosity of mucus in the cervix, which makes it difficult for sperm to enter the uterine cavity. With regular admission, it normalizes the menstrual cycle and helps prevent a number of gynecological diseases, incl. Tumor nature.


Contraception, functional disorders of the menstrual cycle, dysmenorrhea.


Hypersensitivity, pregnancy, hormone-dependent tumors of the mammary glands or uterus, expressed violations of liver function and tumors, diabetes mellitus with vascular complications, thromboembolic diseases (including in the anamnesis), thrombosis of arteries and veins, arterial hypertension (severe form).

pregnancy and lactation

Contraindicated in pregnancy.

Side effects

In rare cases, headache, depression, nausea, diarrhea, tenderness of the mammary glands; With long-term admission, very rarely - chloasma, deterioration in the tolerability of contact lenses.

Dosing and Administration

Inside. For contraception - 1 dragee per day (the interval between the next doses should not exceed 36 hours) for 21 days, then - a 7-day break and a new cycle.

For functional disorders, the dose is selected by the doctor.

Precautionary measures

Be wary appoint patients with varicose veins, phlebitis, multiple sclerosis, epilepsy, endometriosis, liver disease. Admission should be discontinued and consult a doctor when migraine headaches occur for the first time, acute visual impairment, with pregnancy, acute thrombosis, congestion of bile or jaundice, a significant increase in blood pressure (arterial pressure).

storage Conditions

Under normal conditions.

Keep out of the reach of children.

Shelf life

5 years.

Do not use after the expiry date printed on the package.

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