Instruction for use: Metisol

Active substanceThiamazole

ATX codeH03BB02 Thiamazole

Pharmacological group of substance Calcitonin

Thyroid agent [Thyroid and parathyroid hormones, their analogs and antagonists (including antithyroid agents) / 67 /]

Nosological classification (ICD-10)

E05 Thyrotoxicosis [hyperthyroidism]

Von Bazedova's disease, Basedova's disease, Hyperthyroidism, Goiter toxic diffuse, Increased function of the thyroid gland, Thyrotoxic reaction, Toxic diffuse goiter, Toxic goiter, Thyroid enlargement with hyperthyroidism, The phenomenon of iodine-Bashedov

Composition

1 tablet contains thiamazole 5 mg; In blistere 50 pcs., In the package 2 blisters.

pharmachologic effect

Pharmacological action - antithyroid.

It blocks peroxidase, disrupts iodination of thyroid hormones.

Indications

Hyperthyroidism (Basedova disease, etc.), thyrotoxic crisis, preparation for thyroidectomy; Therapy with radioactive iodine.

Contraindications

Hypersensitivity, granulocytopenia, incl. In the anamnesis.

Side effects

Dyspeptic disorders (including a violation of taste), joint, muscle and headaches, dizziness, swelling, allergic skin reactions.

Interaction

Deficiency of iodine increases the effect, excess - weakens.

Dosing and Administration

Inside, adults - in the initial dose of 15-30 mg once a day or 15-60 mg 3 times a day, for maintenance therapy - 5-15 mg per day. Children 4-18 years - 0.5-0.7 mg / kg body weight 3 times a day for maintenance therapy - 0.2-0.3 mg / kg per day; The maximum daily dose is 3 mg / kg.

Precautionary measures

It is necessary to regularly monitor the composition of the cellular elements of the blood. Large thyroid glands with narrowing of the trachea are recommended to be treated for a short time (due to the possible increase in goiter with prolonged therapy).

storage Conditions

In a dry place, at a temperature of 15-25 ° C.

Keep out of the reach of children.

Shelf life

3 years.

Do not use after the expiry date printed on the package.