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Instruction for use: Mesacol

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Active substance Mesalazine

ATX Code A07EC02 Mesalazine

Pharmacological group

NSAIDs - Salicylic acid derivatives

Nosological classification (ICD-10)

K50 Crohn's disease [regional enteritis]

Crohn's disease, Crohn's disease with fistula, Granuloma of the intestine, Granulomatous enteritis, Crohn's disease, Regional ileitis, Terminal Ileitis, Enteritis regional

K51 Ulcerative colitis

Colitis acute ulcerative, Colitis ulcerative, Ulcerative-necrotic colitis, Colitis ulcerative-hemorrhagic nonspecific, Colitis ulcerative and trophic, Colitis ulcerative idiopathic, Colitis ulcerative nonspecific, Nonspecific ulcerative colitis, Proctocolitis ulcers, Hemorrhagic purulent rectoxitis, Rectoccolitis ulcerative-hemorrhagic

Composition and form of release

1 tablet, coated with enteric coating, contains mesalazine 400 mg; in the blister 10 pcs., in the box 5 blisters.

pharmachologic effect

Pharmacological action - anti-inflammatory, antimicrobial.

Anti-inflammatory, antimicrobial.


Nonspecific ulcerative colitis, Crohn's disease.


Hypersensitivity, blood diseases, severe violations of liver function, children's age (up to 2 years).

pregnancy and lactation

During pregnancy, prescribe only if the expected effect justifies the possible risk to the fetus. Caution should be exercised in prescribing the drug to nursing mothers, since 5-aminosalicylic acid is found in breast milk.

Side effects

Dry mouth, nausea, heartburn, vomiting, abdominal pain, loss of appetite, diarrhea, stomatitis, headache, dizziness, insomnia, depression, fatigue, paresthesia, tremor, tinnitus, pericarditis, AV blockade, hypotension, angina, palpitations , tachycardia, dyspnea, hyper or hypotension, alopecia, allergic reactions, changes in urine and blood.

Dosing and Administration

Inside, after eating, with plenty of water. With exacerbation of ulcerative colitis and Crohn's disease - 400-800 mg 3 times a day for 8-12 weeks, with the goal of preventing exacerbations - 400 mg 3 times a day.

Storage Conditions

In a dry, the dark place at a temperature of no higher than 25 C.

Keep out of the reach of children.

Shelf life

4 years.

Do not use after the expiry date printed on the package.

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