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Instructions

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Instruction for use: Mencevax ACWY

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Dosage form: Lyophilizate for the preparation of a solution for subcutaneous administration

Active substance: Vaccine for prevention of meningococcal infections (Vaccinum antimeningococcum)

ATX

J07AH04 Meningococcus A, C, Y, W-135 tetravalent antigen polysaccharide purified

Pharmacological group:

Vaccines, serums, phages and toxoids

Composition and release form

Powder lyophilized to prepare a solution for subcutaneous administration 1 Inoculation dose

Polysaccharides Neisseria meningitidis serogroups A, C, W135 and Y 50 μg each

Auxiliary substances: lactose as a filler

Solvent: 0.9% solution of sodium chloride for injection; For a multi-dose vaccine release form - 0.25% phenol as a preservative

In bottles of glass for 1 dose of vaccine, complete with a solvent in 0.5 ml ampoules; In carton box 1 set,

Or complete with a solvent in 0.5 ml ampoules in a plastic blister; In a carton box 1 blister,

Or complete with a solvent in 0.5 ml glass bottles; In carton box 1 set,

Or complete with a solvent in a glass syringe with 1 or 2 needles in a plastic blister; In a carton box 1 blister,

Or in glass vials of 1 dose of vaccine; In a carton box 100 bottles; Solvent in a separate box: in 0.5 ml ampoules; In a box of cardboard 100 ampoules,

Or in vials of dark glass for 10 doses of the vaccine; In a carton box 50 bottles; Solvent in a separate box: in glass bottles of 5 ml; In a box of cardboard 50 bottles.

Mentsevseks ACWY complies with WHO requirements for biological preparations and for meningococcal polysaccharide vaccines.

Pharmachologic effect

Mode of action - Immunostimulating.

Dosing and Administration

SC, once.

One immunizing dose is 0.5 ml of the diluted vaccine.

The vaccine is dissolved before use with the applied solvent at a rate of 0.5 ml per 1 dose. The bottle is shaken thoroughly until the content is completely dissolved within 1 minute. The dissolved preparation is a clear, colorless solution. If it looks different, and also in the presence of extraneous particles, the vaccine is not used.

After dilution of the lyophilisate with the solvent, the vaccine should be used immediately. It is allowed to store the solution in a vial containing 10 doses, in the refrigerator no more than 8 hours. The solution should be protected from direct sunlight.

A new sterile needle should be used to administer the drug. When using the vaccine in multi-dose packs, a new syringe and needle should be used each time to take the drug. Dissolved drug in multi-dose packs should be used during the working day. The drug should be removed from the bottle with strict adherence to aseptic rules.

The Mentsevsex vaccine ACWY cannot be administered intravenously under any circumstances.

Storage conditions of the drug Mencevax ACWY

At a temperature of 2-8 C (do not freeze). Solvent - at a temperature of 2-25 C.

Keep out of the reach of children.

Shelf life of the drug Mencevax ACWY

2 years. Solvent - 5 years.

Do not use after the expiry date printed on the package.

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