Instruction for use: Levothyroxine sodium + Liothyronine (Levothyroxinum natrium+ Liothyroninum)I want this, give me price
Pharmacological group of substance Calcitonin
Hormones of the thyroid and parathyroid glands, their analogs and antagonists (including antithyroid agents) / 67 /
Nosological classification (ICD-10)
C73 Malignant neoplasm of thyroid
Thyroid cancer, Thyrotropin-Dependent Thyroid Carcinoma, Anaplastic thyroid cancer, Thyroid carcinoma, Medullary thyroid cancer, Thyroid tumors, Papillary thyroid cancer
E03 Other forms of hypothyroidism
hypothyroidism, Hypothyroid conditions, Thyroid hypothyroidism, Diagnosis of hypothyroidism, Myxedema, Primary hypothyroidism, Simple goitre,Spontaneous hypothyroidism, Iatrogenic hypothyroidism
E03.9 Unspecified hypothyroidism
Hypothyroidism, Hypothyroid conditions, Thyroid hypothyroidism, Diagnosis of hypothyroidism, Simple goiter, Hypothyroid edema,Wolf-Chaikoff effect, Congenital hypothyroidism, Secondary hypothyroidism, Hypothyroid obesity, Hypothyroid status, Obstructive hypothyroidism
E04.9 Non-toxic goiter, unspecified
The sporadic goiter, Non-toxic goiter
Substitution therapy, contains L-isomers of T4 and T3, replenishes the deficiency of thyroid hormones. It has anabolic and catabolic action, activates fat metabolism, increases the functional activity of CCC and CNS. In large doses, the production of TTPF by the hypothalamus and TTG by the pituitary is inhibited. More effective than levothyroxine. The latent period of action of levothyroxine is 24-48 h, lyotyronine - 4-8 hours. The optimal combination of drugs is 4: 1 or 5: 1.
Hypothyroidism (of various genesis), thyroid hormone deficiency, goitre recurrence (prophylaxis after resection), euthyroid benign goiter, additional thyrotoxicosis therapy with thyreostatic drugs after reaching the euthyroid status (not during pregnancy). Thyroid cancer (suppressive therapy, after removal of the thyroid gland - replacement).
Hypersensitivity; Myocardial infarction (acute, in anamnesis); Goiter in old age, acute myocarditis, cardiopathy; angina; Adrenal insufficiency; CHF, CHD, severe atherosclerosis; Arrhythmias; arterial hypertension.
Individual, inside, in the morning 30 minutes before breakfast (without chewing, with a small amount of liquid). Adults take 40-100 μg of levothyroxine with 10-20 μg of lyotyronine once a day, increasing the dose at intervals of 2-4 weeks to a maintenance dose (usually 2-2.5 times the initial dose). Children under 14 years - in a dose, 2 times less than adults.
Thyrotoxicosis (tremor of fingers, tachycardia, increased sweating, insomnia, glucosuria, stenocardia, arrhythmias, diarrhea, weight loss, anxiety, tremor), weight gain, alopecia, renal dysfunction, in children - increased convulsive readiness.
Strengthens the effect of indirect anticoagulants, weakens - hypoglycemic drugs.
Kolestyramin reduces the absorption of thyroid hormones.
Rapid intravenous injection of phenytoin increases the concentration in the plasma of free levothyroxine and lyotyronine and, in some cases, contributes to the disturbance of the heart rhythm.
Salicylates, dicoumarol, furosemide (in high doses), clofibrate increase the effect of the drug.