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Instruction for use: L-Thyroxin-Farmak

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Active substance Levothyroxine sodium

ATX Code H03AA01 Calcitonin

Pharmacological groups

Synthetic thyroid hormone [Thyroid and parathyroid hormones, their analogs and antagonists (including antithyroid agents) / 67 /]

Nosological classification (ICD-10)

C73 Malignant neoplasm of thyroid

Thyroid cancer, Thyrotropin-Dependent Thyroid Carcinoma, Anaplastic thyroid cancer, Thyroid carcinoma, Medullary thyroid cancer, Thyroid tumors, Papillary thyroid cancer

E01 Thyroid gland diseases associated with iodine deficiency and similar conditions

Hormonal deficiency of the thyroid gland due to iodine deficiency in the body, Goiter endemic, Iodine deficiency alimentary state, Iodine deficiency disease, Iodine Deficiency, Endemic cretinism

E03 Other forms of hypothyroidism

hypothyroidism, Hypothyroid conditions, Thyroid hypothyroidism, Diagnosis of hypothyroidism, Myxedema, Primary hypothyroidism, Simple goitre,Spontaneous hypothyroidism, Iatrogenic hypothyroidism

E05.0 Thyrotoxicosis with diffuse goiter

Goiter toxic diffuse, Toxic goiter, Diffuse thyrotoxic goiter, Graves disease, Diffuse toxic goiter, Goiter diffuse toxic, Parry's disease, Flanyani disease, Von Bazedova's disease, Toxic diffuse goiter

Composition and form of production

1 tablet contains levothyroxine sodium of 25, 50 or 100 μg; In a contour acheikova packing 10 pcs., In a cardboard pack of 5 packages.

pharmachologic effect

Pharmacological action - replenishing deficiency of thyroid hormones.

Stimulates the metabolism of proteins, fats and carbohydrates, enhances energy processes, cell growth and differentiation, increases the oxygen demand of tissues, the functional activity of the cardiovascular system and the central nervous system.


Hypothyroidism and condition after surgery for thyroid cancer (substitution therapy); Diffuse euthyroid or toxic goiter (prevention and treatment); Prevention of recurrence of nodular goiter after resection of the thyroid gland when reaching the euthyroid state.


Hypersensitivity, untreated hyperthyroidism, myocardial infarction, myocarditis, adrenal insufficiency.

Side effects

From the nervous system and sensory organs: excitability, irritability, insomnia, tremor.

From the cardiovascular system and blood (hematopoiesis, hemostasis): tachycardia, palpitation, arrhythmia, pain in the heart.

Other: diarrhea, weight loss, hyperhidrosis.

Dosing and Administration

Inside, with a small amount of liquid, in the morning 30 minutes before breakfast. Hypothyroidism: the initial dose is 25-50 mcg / day; Maintenance - 100-300 mcg / day. Children the initial dose is 12.5-50 mcg / day, maintaining: at the age of 1 month - 4 mcg / kg, up to 3 months - 25 mcg / day, 3 months - 1 year - 37.5 mcg / day, 1- 5 years - 50 mcg / day, 5-7.5 years - 75-100 mcg / day, 7.5-12 years - 100 mcg / day. Prevention of relapse after removal of goiter: 100 mcg / day. Diffuse euthyroid goiter: 100-200 mcg / day, children aged 1-3 months - 12.5-25 mcg / day, from 3 months to 1 year - 25-37.5 mcg / day, 1-5 years - 25 -62.5 mcg / day, 5-7.5 years - 50-100 mcg / day, 7.5-12 years - 100-150 mcg / day, thyroid cancer after operation: 150-300 mcg / day, with Combined therapy of thyrotoxicosis: 50-100 mcg / day.

storage conditions

In the dark place at a temperature of no higher than 25 C.

Keep out of the reach of children.

Shelf life

3 years.

Do not use after the expiry date printed on the package.

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