Best deal of the week
DR. DOPING

Instructions

Logo DR. DOPING

Instruction for use: Kamiren

I want this, give me price

Trade name of the drug –Kamiren

Active substance: Doxazosinum

Dosage Form: tablets

Composition (per tablet): 1 tablet contains Doxazosin 1, 2 or 4 mg; in blisters of 10 pcs., in a cardboard unit 2 or 3 packs.

Pharmacotherapeutic group: Alpha-blockers

Drugs affecting the metabolism of the prostate gland and correctors urodynamics

ATX C02CA04 Doxazosin

The nosological classification (ICD-10)

I10 Essential (primary) hypertension: hypertension; Arterial hypertension; Arterial hypertension crisis course; Essential Hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Primary hypertension; Arterial hypertension, complications of diabetes; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; arterial Hypertension; malignant Hypertension; Hypertonic disease; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; Isolated systolic hypertension

I15 Secondary hypertension: Arterial hypertension, complications of diabetes; hypertension; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; hypertension; arterial Hypertension; malignant Hypertension; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; hypertension; Arterial hypertension; Arterial hypertension crisis course; renovascular hypertension; Hypertension symptomatic; Renal hypertension; Renovascular hypertension; renovascular hypertension; Symptomatic hypertension

N40 Hyperplasia of prostate gland: Prostate adenoma; BPH; Prostatauxe; prostate Hypertrophy; Dysuric disorders caused by benign prostatic hyperplasia; Dizuricheskie disorder with benign prostatic hyperplasia; Dysuria with prostate cancer; Benign prostatic giperpalaziya; Benign prostatic hyperplasia; Benign prostatic hyperplasia stages 1 and 2; Benign prostatic hyperplasia I degree; Benign prostatic hyperplasia II degree; Benign prostatic hypertrophy; The disease of the prostate gland; Acute urinary retention related to benign prostatic hyperplasia; Benign prostatic hyperplasia stages 1 and 2 in combination with prostatitis; paradoxical ischuria

Pharmacological Properties of Kamiren

Pharmachologic effect - Mode of action - vasodilator, antispasmodic, antihypertensive, lipid-lowering.

Selectively blocks postsynaptic alpha1-adrenergic receptors. Decreases round, total cholesterol, LDL, and triglycerides and increased HDL cholesterol content in serum. It prevents atherosclerosis and CHD, inhibits platelet aggregation. Decreases in left ventricular mass (for long-term treatment). Prevents contraction of smooth muscles of the urethra and the upper part of the muscles of the prostate, it helps to alleviate urination and elimination dizuricheskih symptoms associated with benign prostatic hyperplasia.

Pharmacokinetics

Well absorbed from the gastrointestinal tract, the Cmax is achieved in 1.5-3 hours. Almost entirely associated with plasma proteins, it is metabolized in the liver. T1 / 2 -. 16-22 hours is derived, including as metabolites, mainly in the feces, at least 10% - urine.

Clinical pharmacology

Hypotensive effect is most pronounced for 2-6 hours after drug administration and is continued for 24 hours. The maximum effect is achieved after several weeks of continuous administration. The effect on normal blood pressure slightly. It can be used in patients with renal insufficiency, chronic obstructive pulmonary disease, peripheral arterial disease, gout and diabetes mellitus type 2.

Indications for Kamiren

Hypertension mild or moderate in severity (monotherapy or in combination with other antihypertensive drugs), benign prostatic hyperplasia (symptomatic treatment).

Contraindications for Kamiren

Hypersensitivity, including other derivative quinazoline (prazosin, terazosin), or to other components of the drug, obstruction of the digestive tract or esophagus, narrowing of the gastrointestinal tract of any degree, children's age.

Pregnancy and breast-feeding

Possible, if the expected effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.

Kamiren Dosage and Administration

Inside, regardless of meals.

Arterial hypertension and benign prostatic hyperplasia in patients with hypertension: an initial dose (in the evening before going to bed) - 1 mg per day with gradual increase to 2, 4 and 8 mg 1 time a day at intervals of 1-2 weeks. The usual daily dose - 2-8 mg, the maximum - 16 mg.

Benign prostatic hyperplasia in patients with normal blood pressure: initial dose (in the evening before bedtime)

1 mg / day, gradually increasing to 2, 4 and 8 mg 1 time per day (range - 1-2 weeks). The average daily dose - 2-4 mg, maximum - 8 mg.

Side effect of Kamiren

Cardio-vascular system and blood (blood, hemostasis): arterial hypotension (especially at the beginning of treatment and when increasing the dose of the drug during the transition from a recumbent or seated position to a standing position), very rarely - worsening of angina, myocardial infarction, cerebrovascular stroke, heart rhythm disturbances (although it was not established that the cause is the use of doxazosin); thrombocytopenia.

From the respiratory system: nasal congestion or runny nose, flu-like symptoms, bronchitis, shortness of breath.

From the digestive tract: rarely - nausea, cholestasis, hepatitis, liver function violation.

From the musculoskeletal system: muscle weakness.

From the nervous system and sensory organs: dizziness, headache, fatigue, drowsiness.

For the skin: very rarely - skin rashes, purpura.

Other: hematuria, epistaxis, swelling of the ankles and legs.

Overdose of Kamiren

Symptoms: hypotension, dizziness, fainting.

Treatment: gastric lavage, administration of activated charcoal, laxatives, norepinephrine; Hemodialysis is ineffective.

Interaction

Effect increase beta-blockers, diuretics, calcium channel blockers, ACE inhibitors, nitrates, anesthetics, tricyclic antidepressants and alcohol.

SPECIAL INSTRUCTIONS for Kamiren

With caution use in patients with hepatic insufficiency. In order to avoid orthostatic hypotension, treatment should start with a dose of 1 mg in the evening before bedtime. Care must be taken when changing from a lying or sitting position to a standing position.

Before the treatment of benign prostatic hyperplasia patients should be evaluated by a urologist. Care should be taken while taking drugs that affect hepatic metabolism. Should not be used during the drivers of vehicles and people skills relate to the high concentration of attention.

Storage conditions of Kamiren

The temperature is not above 30 ° C.

Keep out of the reach of children.

Shelf life

5 years.

Do not use beyond the expiration date printed on the package.

Someone from the Belgium - just purchased the goods:
Testoluten intensive course 180 capsules