Instruction for use: Imudon

Dosage form: Semifinished product-solution; lozenges

Active substance: Bacteriolysates [Candida albicans+Corynebacterium pseudodiphtheriticum+Enterococcus faecalis+Enterococcus faecium+Fusobacterium nucleatum subsp]

ATX

L03AX Other immunostimulants

Pharmacological group

Other immunomodulators

The nosological classification (ICD-10)

J02.9 Acute pharyngitis, unspecified: Purulent pharyngitis; Acute rhinopharyngitis; Lymphonodular pharyngitis

J35.0 Chronic tonsillitis: chronic tonsillitis; Inflammatory diseases of the tonsils; Angina chronic; Chronic hypertrophic tonsillitis; Tonsillar angina

K05 Gingivitis and periodontal disease: Gingivitis; Inflammatory Gum Disease; Inflammatory diseases of the oral cavity; Hyperplastic gingivitis; Diseases of the mouth; Catarrhal gingivitis; Erythematous gingivitis; Ulcerative gingivitis; Exacerbation of inflammatory diseases of the pharynx and oral cavity; Bleeding from the gums; Epstein cysts

K05.2 Acute periodontitis: Periodontal disease; Periodontitis; Periodontitis acute; Periodontal disease complicated by gingivitis; Pericoronite

K05.4 Periodontal disease: Alveolar pyorrhea; Amphodontosis; Chronic parodontosis; Superficial and deep periodontitis; Pyorrhea

K12.0 Recurrent aphthae of the mouth: Recurrent aphthous stomatitis; aphthous stomatitis; thrush; Apthae oral mucosa; Ulceration of the mouth; Ulceration of the mucous membranes of the mouth; Oral ulcers; aphthous stomatitis; Bednar aphthae; Aphthae

K14.0 Glossitis

Z100 * CLASS XXII Surgical practice: Abdominal surgery; adenomectomy; Amputation; Coronary angioplasty; Angioplasty of the carotid arteries; Antiseptic skin treatment for wounds; Antiseptic Hand; Appendectomy; atherectomy; Balloon coronary angioplasty; Vaginal hysterectomy; The coronary bypass; Interventions in the vagina and cervix; Interventions on the bladder; Intervention in the mouth; Restoration and reconstructive surgery; Hand hygiene of medical personnel; Gynecologic surgery; Gynecological intervention; Gynecological surgery; Hypovolemic shock during operations; Disinfection of purulent wounds; Disinfection of wounds edges; Diagnostic intervention; Diagnostic procedures; Cervical Diathermocoagulation; Long-surgery; Replacing the fistula catheters; Infection in orthopedic surgery; Artificial heart valve; cystectomy; Short-term outpatient surgery; Short-term operation; Short surgical procedures; Krikotireotomiya; Blood loss during surgery; Bleeding during surgery and in the postoperative period; Kuldotsentez; laser photocoagulation; laser coagulation; retinal laser coagulation; Laparoscopy; Laparoscopy in Gynecology; CSF fistula; Small gynecological operations; Small surgical procedures; Mastectomy and subsequent plastic; mediastinotomy; Microsurgical operations on the ear; Mukogingivalnye operation; suturing; Minor surgery; neurosurgical operation; Immobilization of the eyeball in ophthalmic surgery; testectomy; pancreatectomy; Perikardektomiya; The period of rehabilitation after surgery; The period of convalescence after surgery; Percutaneous transluminal coronary angioplasty; Pleural thoracentesis; Pneumonia postoperative and posttraumatic; Preparation for surgical procedures; Preparation for surgery; Preparation of the surgeon's hands before surgery; Preparation of the colon for surgical procedures; Postoperative aspiration pneumonia in neurosurgical and thoracic surgery; Postoperative nausea; Postoperative bleeding; postoperative granuloma; postoperative shock; The early postoperative period; myocardial revascularization; Radiectomy; gastric Resection; bowel resection; uterine Resection; liver Resection; enterectomy; Resection of part of the stomach; Reocclusion of the operated vessel; Bonding tissues during surgical procedures; Removal of sutures; Condition after eye surgery; Condition after surgery; Condition after surgery in the nasal cavity; Condition after gastrectomy; Status after resection of the small intestine; Condition after tonsillectomy; Condition after removal of the duodenum; Condition after phlebectomy; Vascular surgery; Splenectomy; Sterilization of surgical instruments; Sterilization of surgical instruments; sternotomy; Dental surgery; Dental intervention in periodontal tissues; strumectomy; Tonsillectomy; Thoracic surgery; Thoracic surgery; total gastrectomy; Transdermal intravascular coronary angioplasty; Transurethral resection; Turbinektomiya; Removal of a tooth; cataract surgery; Removal of cysts; tonsillectomy; Removal of fibroids; Removing the mobile primary teeth; Removing polyps; Removing broken tooth; Removal of the uterus body; Removal of sutures; Fistula likvoroprovodyaschih ways; Frontoetmoidogaymorotomiya; Surgical infection; Surgical treatment of chronic limb ulcers; Surgery; The surgery in the anal area; The surgery on the colon; Surgical practice; The surgical procedure; Surgical interventions; Surgery on the gastrointestinal tract; Surgical procedures on the urinary tract; Surgical procedures on the urinary system; Surgical intervention of the genitourinary system; Surgical procedures on the heart; Surgical manipulation; surgery; Surgery on the veins; Surgical intervention; Vascular surgery; Surgical treatment of thrombosis; Surgery; cholecystectomy; Partial gastric resection; hysterectomy; Percutaneous transluminal coronary angioplasty; Percutaneous transluminal angioplasty; Coronary artery bypass; tooth Extirpation; Extirpation of milk teeth; pulpectomy; pulsative cardiopulmonary bypass; tooth Extraction; teeth Extraction; cataract extraction; Electrocoagulation; endourological intervention; episiotomy; Etmoidotomiya; Complications after tooth extraction

Z97.2 Presence of a denture device (full) (partial): Damage to the mucous membrane when wearing dentures; Ulcers when wearing dentures; Ulceration of dentures; Dentures; Bedsores from removable dentures; Irritation from dentures; Irritation of the oral mucosa with dentures and braces; When wearing dentures; Gum pain when wearing dentures

Composition and release form

Tablets for resorption - 1 table.

A mixture of bacterial lysates (dry matter): Streptococcus pyogenes group A, Enterococcus faecalis, Enterococcus faecium, Streptococcus sanguis, Staphylococcus aureus subsp. Aureus, Klebsiella pneumoniae subsp. Pneumoniae, Corynebacterium pseudodiphtheriticum, Fusobacterium nucleatum subsp. Nucleatum, Candida albicans, Lactobacillus acidophilus, Lactobacillus fermentum, Lactobacillus helveticus, Lactobacillus delbrueckii subsp. Lactis 50 mg

Auxiliary substances: lactose; Mannitol; glycine; Povidone; Sodium saccharinate; Sodium bicarbonate; Sodium deoxycholate; Anhydrous citric acid; Powder of mint; Magnesium stearate; Sodium merthiolate (preservative) - no more than 12.5 μg / tab.

In a blister of 8 pcs .; In a box of cardboard 5 blisters.

Description of dosage form

White or almost white tablets of a flat-cylindrical shape, with a smooth shiny surface, with bevelled edges, without pores.

Characteristic

A polyvalent antigenic complex is a mixture of bacterial lysates whose composition corresponds to pathogens most often causing inflammatory processes in the oral cavity and pharynx.

Pharmachologic effect

Mode of action - immunomodulating.

Pharmacodynamics

Immunostimulating drug of bacterial origin for topical use in dentistry and otorhinolaryngology. Activates phagocytosis, promotes an increase in the number of immunocompetent cells, increases the production of lysozyme, interferon and secretory immunoglobulin A in saliva.

Indications of the Imudon

Treatment and / or prevention:

Superficial and deep periodontitis, periodontitis, stomatitis, glossitis, aphthous stomatitis;

Inflammatory and infectious diseases of the oral cavity and pharynx;

Erythematous and ulcerative gingivitis;

Dysbacteriosis of the oral cavity;

pharyngitis;

chronic tonsillitis;

Ulceration caused by dentures;

Infection after tooth extraction, implantation of artificial dental roots;

Preoperative preparation for tonsillectomy;

Postoperative period after tonsillectomy.

Contraindications

Increased individual sensitivity to the drug or its components;

Children's age till 3 years.

Application in pregnancy and breastfeeding

Information on the use of Imudon in pregnant women is not enough. Corresponding data on animal experiments and epidemiological studies are lacking.

It is not recommended to take Imudon® during pregnancy or lactation.

Side effects

Rarely:

From the digestive tract: nausea, vomiting, abdominal pain;

Allergic reactions: rash, hives, angioedema.

Interaction

Imudon ® can be used with drugs from other groups.

Dosing and Administration

Inside.

Adults and teenagers over 14 years of age

In acute inflammatory diseases of the oral cavity and pharynx and exacerbation of chronic diseases: - 8 tab. in a day. The tablets dissolve (not chewing) in the oral cavity with an interval of 1 hour. The average duration of the course of treatment is 10 days.

For the prevention of chronic inflammatory diseases of the oral cavity and pharynx: 6 table. in a day. The tablets dissolve (not chewing) in the oral cavity with an interval of 2 hours. The course duration is 20 days.

Children from 3 to 14 years old

In the treatment of acute and exacerbation of chronic inflammatory diseases of the oral cavity and pharynx, as well as for prophylaxis: according to 6 tables. in a day. Tablets dissolve (not chewing) in the oral cavity with an interval of 2 hours. Duration of treatment for acute diseases is 10 days, for the prevention of chronic - 20 days.

It is recommended to conduct preventive courses for Imudon® 3-4 times a year.

Overdose

The cases of an overdose of Imudon ® are not described.

Special instructions

Children from 3 to 6 years of age necessarily resolve the tablets in the oral cavity under the supervision of an adult!

If necessary, rinse the mouth can be no earlier than 1 hour after intake (so as not to reduce the therapeutic activity of the drug). When the drug is prescribed for patients who observe a salt-free or low-salt diet, it must be taken into account that 1 table. Imudon® contains 15 mg of sodium.

There is no evidence of the need for any restrictions on activities related to driving or other mechanisms during the treatment period.

Manufacturer

Solvay Pharmaceuticals, France.

Storage conditions of the drug Imudon

At a temperature not higher than 25 ° C.

Keep out of the reach of children.

The shelf life of the drug Imudon

3 years.

Do not use beyond the expiration date printed on the package.