Instruction for use: Hydrocortisone + Fusidic acid (Hydrocortisonum +Acidum fusidicum)

Pharmacological group

Glucocorticosteroids in combinations

Pharmacotherapy

Combined drug. Hydrocortisone - GCS, has anti-inflammatory and anti-allergic effect. It inhibits the release of cytokines (interleukins and interferon) from lymphocytes and macrophages, inhibits the release of eosinophils by inflammatory mediators, reduces the metabolism of arachidonic acid. Stimulating steroid receptors induces the formation of lipocortin. Reduces inflammatory cell infiltrates, reduces the migration of leukocytes and lymphocytes to the area of inflammation. Does not cause suppression of the hypothalamic-pituitary-adrenal system. Fusidic acid is an antibacterial agent that acts bacteriostatically (suppresses protein synthesis in a microbial cell). Highly active against Staphylococcus spp., Neisseria meningitidis, Neisseria gonorrhoeae, less active against Streptococcus spp., Incl. Streptococcus pneumoniae, Staphylococcus spp. (Resistant to penicillins, streptomycin, chloramphenicol, erythromycin); Neisseria spp., Haemophilus spp., Moraxella spp. And Corynebacterium. Not active against Escherichia coli, Salmonella spp., Proteus spp. And other gram-negative bacteria, as well as protozoa and fungi.

Indications

Eczema, seborrheic and contact (simple and allergic) dermatitis; Simple chronic lichen (limited neurodermatitis), atopic dermatitis; Discoid lupus erythematosus.

Contraindications

Hypersensitivity, primary bacterial, viral and fungal skin diseases; Perioral dermatitis; Pink acne, skin tuberculosis, syphilis (skin manifestations).

Carefully

When applied to large surfaces - pregnancy, lactation.

Dosing

Outer, apply to the affected area of the skin a thin layer 3-4 times a day for 2 weeks.

Side effect

Allergic reactions. With prolonged use on extensive surfaces - striae, skin atrophy, local hirsutism, hypopigmentation, systemic manifestations.

Special instructions

Avoid contact with eyes and mucous membranes.