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Instruction for use: Fortecortin

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Active substance: Dexamethasone

ATX Code H02AB02Dexamethasone

Pharmacological group

Glucocorticosteroids

The nosological classification (ICD-10)

D69.3 Idiopathic thrombocytopenic purpura

Werlhof's disease, Idiopathic autoimmune thrombocytopenia, Idiopathic thrombocytopenic purpura of adults, Idiopathic thrombocytopenic purpura in adults, Immune idiopathic thrombocytopenic purpura, Immune thrombocytopenia, Bleeding in patients with thrombocytopenic purpura, Evans Syndrome, Thrombocytopenic purpura, Thrombocytopenia of immune origin, Chronic idiopathic thrombocytopenic purpura, Essential thrombocytopenia, Autoimmune thrombocytopenic purpura in pregnancy, Posttransfusion purpura

J30 Vasomotor and allergic rhinitis

Allergic rinopatiya, Allergic rhinosinusopathy, Allergic respiratory diseases, Allergic rhinitis, nasal allergy, Seasonal Allergic Rhinitis, Vasomotor rhinitis, Long-allergic rhinitis, Perennial allergic rhinitis, Perennial allergic rhinitis, Year-round or seasonal allergic rhinitis, Year-round allergic rhinitis nature, Rhinitis allergic vasomotor, Exacerbation of pollen allergy in the form of Syndrome rinokonyunktivalnogo, Acute allergic rhinitis, Edema of the nasal mucosa, Edema of the nasal mucosa, Swelling of the mucosa of the nasal cavity, Swelling of the nasal mucosa, Swelling of the nasal mucosa, pollen disease, Permanent allergic rhinitis, rhinoconjunctivitis, rhinosinusitis,rhinosinusopathy, Seasonal allergic rhinitis, Seasonal Allergic Rhinitis, Haymarket rhinitis, Chronic allergic rhinitis, Allergic respiratory diseases

J45 Asthma

Asthma physical effort, status asthmaticus, Bronchial asthma, Asthma lung flow, Bronchial asthma with obstruction of sputum discharge, Bronchial asthma heavy currents, Bronchial asthma physical effort, hypersecretory asthma, Hormone-dependent form of bronchial asthma, Relief of asthma attacks in bronchial asthma, Non-allergic asthma, nocturnal asthma, Exacerbation of asthma, Asthma attacks, Endogenous forms of asthma, Night asthma, Cough with bronchial asthma

K50 Crohn's disease [regional enteritis]

Crohn's disease, Crohn's disease with fistula, Granuloma of the intestine, Granulomatous enteritis, Crohn's disease, Regional ileitis, Terminal Ileitis, Enteritis regional

K51 Ulcerative colitis

Colitis acute ulcerative, Colitis ulcerative, Ulcerative-necrotic colitis, Colitis ulcerative-hemorrhagic nonspecific, Colitis ulcerative and trophic, Colitis ulcerative idiopathic, Colitis ulcerative nonspecific, Nonspecific ulcerative colitis, Proctocolitis ulcers, Hemorrhagic purulent rectoxitis, Rectoccolitis ulcerative-hemorrhagic

L10 Pemphigus [pemphigus]

Benign pemphigoid of mucous membranes, Bubble dermatosis, Pemphigus, Dermatitis, vesicular, Benign pemphigus, Ordinary pemphigus, Pemphigus, Bubble dermatitis, Family benign pemphigus Hailey-Hailey

L20 Atopic dermatitis

Itchy atopic eczema, Common neurodermatitis, Allergic skin diseases, Allergic skin diseases of non-infectious etiology, Allergic skin diseases of non-microbial etiology, Allergic skin diseases, Allergic skin lesions, Allergic manifestations on the skin, Allergic dermatitis, Allergic diathesis, Allergic itching dermatosis, Allergic Skin Disease, Allergic skin irritation, Dermatitis allergic, Atopic dermatitis, Dermatosis allergic, Diathesis exudative, Skin Allergic Disease, Skin allergic reaction to medicinal and chemical preparations, Skin reaction to medication, Skin and allergic disease, Acute eczema, Chronic atopic dermatitis, Exudative diathesis, Itching allergic dermatosis

L50 Urticaria

Idiopathic chronic urticaria, Injury Urticaria, Chronic urticaria, Hives of the newborn

M30-M36 Systemic involvement of connective tissue

Collagenoses

M79.0 Other unspecified rheumatism

Degenerative rheumatic disease, Degenerative and rheumatic diseases of the tendons, Degenerative rheumatic diseases, Localized forms of rheumatism of soft tissues, Rheumatism, Rheumatism with a pronounced allergic component, Rheumatism of the articular and extraarticular, Rheumatic attack, Rheumatic complaints, Rheumatic diseases, Rheumatic disease of the spine, Relapses of rheumatism, Articular and extra-articular rheumatism, Articular and muscular rheumatism, Articular rheumatism, Articular syndrome with rheumatism, Chronic rheumatic pain, Chronic articular rheumatism, Rheumatoid diseases, Rheumatic diseases of the intervertebral disc

N04 Nephrotic syndrome

Nephrosis, Edema of the kidneys, Nephrotic syndrome, Lipoid nephrosis, Nephrotic syndrome without uremia, Acute nephrotic syndrome, Edematic syndrome of renal genesis, Renal form of diabetes insipidus, Segmental glomerulonephritis, Focal glomerulonephritis, Family Nephrotic Syndromes, Chronic nephrotic proteinuric syndrome, Lipiduria, Jade hereditary, Nephrotic-proteinuric syndrome

T78.3 Angioedema

Edema Quincke, Laryngeal exacerbation with angioneurotic edema, Recurrent angioedema, Allergic edema, Recurrent swelling of Quincy

T78.4 Allergy, unspecified

Allergic reactions to insulin, Allergic reactions to insect stings, Allergic reactions similar to systemic lupus erythematosus, Allergic diseases, Allergic diseases of mucous membranes, Allergic diseases and conditions resulting from increased release of histamine, Allergic diseases of mucous membranes, Allergic symptoms, Allergic symptoms in the mucous membranes, Allergic reactions, Allergic reactions caused by insect bites, Allergic reactions, Allergic conditions, Allergic laryngeal edema, allergopathy, allergic conditions, Allergy, House dust allergy, Anaphylaxis, Cutaneous reactions to medications, Skin reaction to insect stings, Cosmetic allergy, Drug allergy, Acute allergic reaction, Laryngeal edema allergic genesis and background radiation, Food and drug allergy

Composition and form of release

1 tablet Fortecortin contains dexamethasone 0.5 or 4 mg; In a blistere of 10 pcs., In a cardboard package 2 blisters.

1 ml solution for injection Fortecortin mono contains dexamethasone-21-dihydrogenphosphate disodium salt 4.37, 8.74 or 43.72 mg, which corresponds to 4, 8 or 40 mg dexamethasone-21-dihydrogen phosphate; In ampoules of 1 and 2 ml (4 mg / ml) or 5 ml (8 mg / ml), in the package, respectively 3 or 1 pc.

pharmachologic effect

Pharmacological action - anti-inflammatory, anti-allergic, immunosuppressive.

Indications

Hypocorticism, circulatory collapse, shock, asthmatic status, bronchial asthma, laryngeal edema, progressive ophthalmopathy against thyrotoxicosis, leukemia, lymphosarcoma, serum sickness, dermatitis, rheumatism, rheumatoid arthritis, erythroderma, pemphigus, eczema, sarcoidosis, collagenoses, ulcerative colitis, Malignant tumors, congenital adrenogenital syndrome, autoimmune hemolytic anemia, thrombocytopenia, bone marrow aplasia, agranulocytosis.

Contraindications

Hypersensitivity, systemic mycoses.

Side effects

Increased appetite, obesity, hirsutism, osteoporosis, decreased immunity, glaucoma, increased excitability, psychoses, seizures, peptic ulcer, chronic infections, dysmenorrhea, diabetes mellitus, suppression of adrenal cortex function, hemorrhagic pancreatitis, hypokalemia.

Dosing and Administration

Inside. In severe cases, at the beginning of treatment, up to 10-15 mg per day, the maintenance dose is 2 -4.5 mg per day. With asthmatic status and acute allergic diseases - 2-3 mg per day, with adrenogenital syndrome - 1-1.5 mg. The average daily dose of more than 2-3 mg is divided into 2-3 doses. In / in (intravenously) slowly (within 4-5 minutes), intravenously, intravenously (intramuscularly), intra-articularly. Within a day, inject 1-5 ml of the drug 3-4 times a day; Dose for intra-articular injection (1-2 ml) is administered at intervals of 2-3 days to 1-2 weeks. Parenteral administration is usually used for 3-4 days, after which they switch to oral maintenance therapy.

storage Conditions

At a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life

Tablets 0.5 mg - 5 years.

Tablets 4 mg - 5 years.

Injection for 4 mg / ml - 3 years.

Injection for 8 mg / 2 ml - 3 years.

Injection for 40 mg / 5 ml - 3 years.

Do not use after the expiry date printed on the package.

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