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Active substance Fluocinolone acetonide

ATX codeD07AC04 Fluocinolone acetonide

Pharmacological group

Pharmacological group - Glucocorticosteroids

Nosological classification (ICD-10)

L20 Atopic dermatitis

Itchy atopic eczema, Common neurodermatitis, Allergic skin diseases, Allergic skin diseases of non-infectious etiology, Allergic skin diseases of non-microbial etiology, Allergic skin diseases, Allergic skin lesions, Allergic manifestations on the skin, Allergic dermatitis, Allergic diathesis, Allergic itching dermatosis, Allergic Skin Disease, Allergic skin irritation, Dermatitis allergic, Atopic dermatitis, Dermatosis allergic, Diathesis exudative, Skin Allergic Disease, Skin allergic reaction to medicinal and chemical preparations, Skin reaction to medication, Skin and allergic disease, Acute eczema, Chronic atopic dermatitis, Exudative diathesis, Itching allergic dermatosis

L21 Seborrheic dermatitis

Dermatitis seborrheic, Increased sebum separation, Seborrheic Eczema, Seborrheic dermatitis of the scalp, Seborrheic pyodermatitis, Seborrhea, Eczema seborrheic

L30.9 Dermatitis, unspecified

Allergic dermatoses complicated by a secondary bacterial infection, Anal eczema, Bacterial maturation, Varicose Eczema, Venous dermatitis, Inflammation of the skin, Inflammation of the skin upon contact with plants, Inflammatory Skin Diseases, Inflammatory skin reactions, Inflammatory processes of the skin, Hypostatic dermatitis, Fungal Eczema, Fungal dermatosis, Dermatitis, Dermatitis is stagnant, Dermatitis and eczema in the anal area, Dermatitis acute contact, Perianal dermatitis, Dermatosis, Dermatosis of the scalp, Dermatosis of psoriasis, Dermatosis with persistent itching, Dermatoses, Dermatoses itchy, Other itching dermatoses, Significant eczematous manifestations, Itching with, dermatoses, Itching eczema, True eczema, Skin reaction to insect bites,Skin itching with dermatosis, Constitutional eczema, Weeping eczema, Drowsing inflammatory skin disease, Dying Infectious-Inflammatory Skin Disease, Non-allergic dermatitis, Nummular eczema, Acute contact eczema, Acute inflammatory skin disease, Acute dermatosis, Acute severe dermatosis, Perianal dermatitis, Superficial dermatosis, Subacute Contact Eczema, Simple dermatitis, Occupational dermatitis, Psychogenic dermatosis, Bubble dermatitis of newborns, Pustular eruptions, Irritation and redness of the skin, Low-flammable eczema, Dry atrophic eczema, Dry eczema, Toxic dermatitis, Ear eczema like dermatitis, Chronic eczema, Chronic dermatosis, Chronic common dermatosis, Scaly papular dermatosis, Eczema, Eczema anal region, Eczema of the hands, Eczema Contact, Eczema lichenized, Eczema Nummular, Eczema acute, Eczema acute contact, Eczema subacute, Eczematous dermatitis, Eczema-like rashes, Ecome exogenous, Endogenous eczema, Gluteal dermatitis, Restricted itchy dermatitis

L40 Psoriasis

Chronic psoriasis with diffuse plaques, Generalized psoriasis, Psoriasis of the scalp, Psoriasis of the scalp, Generalized form of psoriasis, Psoriasis dermatitis, Psoriasis complicated by erythroderma, Invalidative psoriasis, Isolated psoriatic plaque, Exfoliative psoriasis, Psoriatic Erythroderma, Psoriasis with eczematosis, Hyperkeratosis in psoriasis,Inverse psoriasis,Psoriasis eczematous, Dermatosis of psoriasis, Psoriasis of the genitals, Psoriasis with lesions of hairy areas of skin, Erythrodermal psoriasis, Chronic psoriasis of the scalp, Chronic psoriasis, Ordinary psoriasis, Refractory psoriasis, Kebner phenomenon, Scaly lichen

L43 Red Leaf Flat

Lishay Wilson, Erosive-ulcerative form of red flat lichen, Warty forms of red lichen, Red lichen, Flat lichen, Kebner phenomenon

Composition and form of release

Ointment 1 g

Fluocinolone acetonide 0.25 mg

Auxiliary substances: propylene glycol; Citric acid; Lanolin anhydrous; Petroleum jelly white

In tubes of 15 g; In a pack of cardboard 1 tuba.

Gel 1 g

Fluocinolone acetonide 0.25 mg

Auxiliary substances: propylene glycol; Ethanol; Disodium ethylenediaminetetraacetic acid (Trilon B); Citric acid; Methylhydroxybenzoate; Propylhydroxybenzoate; Carbopol 940; Triethanolamine; purified water

In tubes of 15 grams, in a pack of cardboard 1 tuba.

pharmachologic effect

Pharmacological action - anti-inflammatory, antiallergic, antipruritic, antiexudative.

Oppresses phospholipase A2, reduces the synthesis of PG (prostaglandins) and the isolation of macrophage chemotactic factor.


It has a pronounced anti-inflammatory, antiallergic and antipruritic effect, reduces the migration of macrophages and lymphocytes to the inflammation focus, stabilizes the lysosome membranes and prevents the release of lysosomal enzymes, blocks the release of sensitized mast cells and basophils of histamine and other biologically active substances. It is 40 times more active than hydrocortisone.


Severe inflammatory and allergic diseases of the skin and mucous membranes (including those resistant to therapy with other corticosteroids): neurodermatitis, eczema, psoriasis, red flat lichen, seborrheic dermatitis.


Hypersensitivity; acne; Bacterial (including tuberculosis), fungal, viral and tumor skin diseases.

pregnancy and lactation

Not recommended during pregnancy.

Side effects

Skin and subcutaneous fat atrophy, lupus-like syndrome with mild course, appearance or exacerbation of symptoms of red flat lichen, epithelialization disorders, delayed healing of wounds and ulcerative lesions, petechiae, steroid purpura, striae, hirsutism, female hair loss, maculopapular skin rash.

Dosing and Administration

Outwardly. Apply to the affected surface, lightly rubbing, 1-2 times a day, no more than 2 g / day. With psoriasis, the use of an occlusive dressing is possible. The duration of the course is no more than 1-2 weeks. On the skin, the face is applied very carefully and not more than 1 week.

Children older than 2 years - with caution, only once a day, on small areas of the skin.

Precautionary measures

Do not use for a long time and in large areas (possibly the manifestation of systemic effects). If skin irritation occurs at the site of the ointment application, it should be discarded. When dryness and tightening sensation, the skin is lubricated with 5% salicylic oil.

storage Conditions

At a temperature not higher than 25 C.

Keep out of the reach of children.

Shelf life

Ointment for external use 0.025% - 5 years.

Gel for external use 0.025% - 3 years.

Do not use after the expiry date printed on the package.

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