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Instruction for use: Ectrokad

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Active substance: Estriol

Code: G03CA04 Estriol

Pharmacological groups

Estrogens, gestagens; their homologues and antagonists

Nosological classification (ICD-10)

E28.3 Primary ovarian failure

Hypogonadism of the ovary (primary), Hypofunction of the ovaries, Estrogen deficiency, Insufficient estrogen content in the body, Insufficiency estrogenic, Insufficiency of estrogens, Primary dysfunction of the ovaries, Estrogen-deficient conditions

N30.8 Other cystitis

N72 Inflammatory diseases of the cervix uteri

Muco-purulent cervicitis, Inflammatory diseases of female genitalia, Inflammatory diseases of female genital organs, Gonorrheal cervicitis, Infection of the genitals, Non-gonorrhal cervicitis, Uncomplicated cervicitis, Nonspecific cervicovaginitis, Acute gonorrhea cervicitis, Cervicovaginitis, Cervicitis, Exocervicitis, Bacterial colpitis

N76 Other inflammatory diseases of the vagina and vulva

Atrofic vulvovaginitis, Vulvovaginitis bacterial, Vulvovaginitis estrogen-deficient, Bacterial vaginosis, Vaginitis, Vaginitis bacterial, Inflammatory diseases of the vagina and vulva, Inflammatory diseases of female genitalia, Inflammatory diseases of female genital organs, Vulvit, Vulvovaginitis, Gardnerella, Fungal vulvovaginitis in girls and virgins, Infection of the vagina, Infection of the genitals, Colpitis, Violation of purity of the vaginal secretion, Nonspecific cervicovaginitis, Nonspecific vulvitis, Nonspecific vulvovaginitis, Nonspecific colpitis, Recurrent nonspecific bacterial vaginosis, Senylic coverings, Mixed Colpus, Chronic vaginitis, Vulvovaginal infections, Bacterial vaginitis, Mixed vaginal infections

N89 Other non-inflammatory diseases of the vagina

Ulcers in the vagina

N90.5 Atrophy of the vulva

Dystrophy of the vulva, Crown of the vulva, Vaginal narrowing

N94.1 Dyspareunia

N95.2 Postmenopausal atrophic vaginitis

Atrofic vulvovaginitis, Vulvovaginitis estrogen-deficient, Atrophied vagina, Atrophic changes in the organs of the urogenital system in women, Atrophy of the mucous membrane of the lower sections of the genito-urinary tract, caused by estrogen deficiency Atrophy of the mucous membranes of the urino-genital organs, Burning and dryness of the vagina, Violation of the composition of the vaginal secretion in menopause, Dryness of the mucous membrane of the vagina, Degenerative disorders of the female sexual sphere, Atrophic vaginitis, Atrophic vulvovaginitis, Atrophy of lower urinary tract, Atrophy of urogenital organs, Dryness of the mucous membranes of the urino-genital organs, Dryness of the mucous membranes of the urogenital tract, Dryness of the vagina

R32 Urinary incontinence unspecified

daytime enuresis, Idiopathic bladder instability, Urinary incontinence, nocturia, The disorder of the bladder sphincter function, Spontaneous urination, Mixed forms of urinary incontinence, Functional disorders of micturition, Functional micturition disorders, Functional enuresis in children, Enuresis

Z100 * CLASS XXII Surgical practice

Abdominal surgery, adenomectomy, Amputation, Coronary angioplasty, Angioplasty of the carotid arteries, Antiseptic skin treatment for wounds, Antiseptic Hand, Appendectomy, atherectomy, Balloon coronary angioplasty, Vaginal hysterectomy, The coronary bypass, Interventions in the vagina and cervix, Interventions on the bladder, Intervention in the mouth, Restoration and reconstructive surgery, Hand hygiene of medical personnel, Gynecologic surgery, Gynecological intervention, Gynecological surgery, Hypovolemic shock during operations, Disinfection of purulent wounds, Disinfection of wounds edges, Diagnostic intervention, Diagnostic procedures, Cervical Diathermocoagulation, Long-surgery, Replacing the fistula catheters, Infection in orthopedic surgery, Artificial heart valve, cystectomy, Short-term outpatient surgery, Short-term operation, Short surgical procedures, Krikotireotomiya, Blood loss during surgery, Bleeding during surgery and in the postoperative period, Kuldotsentez, laser photocoagulation, laser coagulation, retinal laser coagulation, Laparoscopy, Laparoscopy in Gynecology, CSF fistula, Small gynecological operations, Small surgical procedures, Mastectomy and subsequent plastic, mediastinotomy, Microsurgical operations on the ear, Mukogingivalnye operation, suturing, Minor surgery, neurosurgical operation, Immobilization of the eyeball in ophthalmic surgery, testectomy, pancreatectomy, Perikardektomiya, The period of rehabilitation after surgery, The period of, convalescence after surgery, Percutaneous transluminal coronary angioplasty, Pleural thoracentesis, Pneumonia postoperative and posttraumatic, Preparation for surgical procedures, Preparation for surgery, Preparation of the surgeon's hands before surgery, Preparation of the colon for surgical procedures, Postoperative aspiration pneumonia in neurosurgical and thoracic surgery, Postoperative nausea, Postoperative bleeding, postoperative granuloma, postoperative shock, The early postoperative period, myocardial revascularization, Radiectomy, gastric Resection, bowel resection, uterine Resection, liver Resection, enterectomy, Resection of part of the stomach, Reocclusion of the operated vessel, Bonding tissues during surgical procedures, Removal of sutures, Condition after eye surgery, Condition after surgery, Condition after surgery in the nasal cavity, Condition after gastrectomy, Status after resection of the small intestine, Condition after tonsillectomy, Condition after removal of the duodenum, Condition after phlebectomy, Vascular surgery, Splenectomy, Sterilization of surgical instruments, Sterilization of surgical instruments, sternotomy, Dental surgery, Dental intervention in periodontal tissues, strumectomy, Tonsillectomy, Thoracic surgery, total gastrectomy, Transdermal intravascular coronary angioplasty, Transurethral resection, Turbinektomiya, Removal of a tooth, cataract surgery, Removal of cysts, tonsillectomy, Removal of fibroids, Removing the mobile primary teeth, Removing polyps, Removing broken tooth, Removal of the uterus body, Removal of sutures, Urethrotomy, Fistula likvoroprovodyaschih ways, Frontoetmoidogaymorotomiya, Surgical infection, Surgical treatment of chronic limb ulcersm, Surgery, The surgery in the anal area, The surgery on the colon, Surgical practice, The surgical procedure, Surgical interventions, Surgery on the gastrointestinal tract, Surgical procedures on the urinary tract, Surgical procedures on the urinary system, Surgical intervention of the genitourinary system, Surgical procedures on the heart, Surgical manipulation, surgery, Surgery on the veins, Surgical intervention, Vascular surgery, Surgical treatment of thrombosis, cholecystectomy, Partial gastric resection, transabdominal hysterectomy, Percutaneous transluminal coronary angioplasty, Percutaneous transluminal angioplasty, Coronary artery bypass, tooth Extirpation, Extirpation of milk teeth, pulpectomy, pulsative cardiopulmonary bypass, tooth Extraction, teeth Extraction, cataract extraction, Electrocoagulation, endourological intervention, episiotomy, Etmoidotomiya, Complications after tooth extraction

Z98.8 Other specified poslehirurgicheskie state

Suppurative complications in the postoperative period, Suppurative complications of surgery, Postoperative liver dysfunction, Postoperative vomiting, Postoperative complications, The postoperative period, The early postoperative period

Composition and form of release

Vaginal suppositories 1 supp.

Estriol 0.5 mg

auxiliary substances: cetomacrogol; glycerol monoricinoleate; hard fat

in a blister of 5 pcs .; in a pack of cardboard 2 blisters.

pharmachologic effect

The pharmacological action is estrogenic.


Diseases caused by insufficient estrogen content in the body: involution (atrophy) of the vagina and vulva, accompanied by itching, burning and dryness of the vagina, pain during intercourse (dyspareunia), colpitis, vulvitis, cervicitis, leucorrhoea, vaginal narrowing, sores in the vagina and on the cervix Uterus resulting from pressure or stretching, concomitant therapy with vaginal infections and involuntary urination (urinary incontinence), lower urinary tract atrophy (urethrocystitis), pre- and postoperative treatment with vagina nyh operations, diagnostics in unclear results of vaginal smear, if there is change in the cellular composition of the picture on the background of signs of involution.


Hypersensitivity, bleeding of unclear etiology in the genital area, malignant tumors of the uterus or mammary glands, caused by estrogen deficiency.

Use with caution when the first signs of migraine appear, frequent unusually strong attacks of headache, the appearance of the first signs of phlebitis or phenomena of a thromboembolic character, the appearance of cholestatic jaundice, a sharp increase in blood pressure, acute visual impairment.

pregnancy and lactation

Not recommended for pregnancy.

During breastfeeding - with caution, in significantly reduced doses, because Estriol partially penetrates into breast milk.

Side effects

Irritation of the vagina, accompanied by itching, burning and redness.

At the beginning of treatment - smearing spotting from the vagina, tenderness and tension of the mammary glands, hypersecretion of cervical mucus, leucorrhoea, fluid retention and associated temporary weight gain, nausea and other mild gastrointestinal disorders, rarely migraine headache, very rarely - a feeling of heaviness in the legs, cramps of the calf muscles.


The simultaneous use of barbiturates, anticonvulsant drugs (eg hydantoins), certain antibiotics (eg cephalosporins, neomycin) may decrease effectiveness.

Dosing and Administration

Intravaginal, if not prescribed otherwise, 1 supp. / Day.

Precautionary measures

Treatment with the drug should be carried out only under constant medical supervision with gynecological examinations (especially with prolonged and repeated bleeding from the vagina).

When detecting a vaginal infection, it is necessary to simultaneously treat it.

storage Conditions

At a temperature of no higher than 25 C.

Keep out of the reach of children.

Shelf life

3 years.

Do not use after the expiry date printed on the package.

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