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DR. DOPING

Instructions

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Instruction for use: Driptane

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Active substance: Oxybutynin

ATX Code

G04BD04 Oxybutynin

Pharmacological group

Antispasmodics [m-Cholinolytics]

Antispasmodics [Spazmolitiki myotropic]

The nosological classification (ICD-10)

N31 Neuromuscular dysfunction of bladder, not elsewhere classified

Overactive bladder syndrome, Idiopathic violation of detrusor function, detrusor dysfunction, Spasmodic neurogenic bladder dysfunction

R32 Urinary incontinence unspecified

daytime enuresis, Idiopathic bladder instability, Urinary incontinence, nocturia, The disorder of the bladder sphincter function, Spontaneous urination, Mixed forms of urinary incontinence, Functional disorders of micturition, Functional micturition disorders, Functional enuresis in children, Enuresis

Structure and Composition

Tablets 1 tab.

5 mg of oxybutynin hydrochloride

Other ingredients: MCC; calcium stearate; lactose anhydrous

in blister 30 pcs .; In the paper cartons 1 blister.

The drug forms

Tablets of white color, round, biconcave, with Valium on one party.

pharmachologic effect

Mode of action - antispasmodic, myotropic.

pharmacodynamics

It relaxes the detrusor (muscle that reduces the bladder). It provides direct antispasmodic myotropic and m-anticholinergic action. Increases the capacity of the bladder, reduces the incidence of detrusor contractions, holding back the urge to urinate.

Pharmacokinetics

Cmax after oral administration is achieved after 45 minutes. The concentration is proportional to the applied dose. T1 / 2 is less than 2 hours (increases in elderly patients).

Indications

urinary incontinence associated with bladder instability function, impaired either by nature neurogenic disorders (detrusor hyperreflexia), such as disseminated sclerosis or spina bifida, or in idiopathic detrusor function disorders (incontinence engine);

nocturnal enuresis in children older than 5 years.

Contraindications

Hypersensitivity to the drug;

angle-closure glaucoma;

obstruction of the gastrointestinal tract, intestinal, expansion of the colon, ulcerative colitis;

myasthenia gravis;

obstructive uropathy;

bleeding;

lactation;

Children up to age 5 years.

Pregnancy and breast-feeding

During pregnancy DriptaneŽ apply only under strict conditions. If necessary, use during lactation should decide the issue of termination of breastfeeding.

Side effects

Nausea, constipation, diarrhea, discomfort in the abdomen, urinary retention, drowsiness or insomnia, weakness, headache, dizziness, arrhythmia, impaired vision (mydriasis, paralysis of accommodation), increased intraocular pressure, decreased sweating, dry mouth, impotence, allergic reactions.

Dosing and Administration

Inside. Adults - 5 mg 2-3 times per day, children and elderly patients - 5 mg 2 times a day.

Overdose

Symptoms: CNS arousal (anxiety, tremors, increased nervous irritability, convulsions, delirium, hallucinations), fever, nausea, vomiting, tachycardia, decreased blood pressure, respiratory failure, paralysis, coma.

Treatment: should maintain breathing, vomit or to gastric lavage, activated charcoal, and assign a saline laxative. For regression anticholinergic symptoms of intoxication using cholinesterase blockers (physostigmine). In marked anxiety or excitation - in / in a 10 mg diazepam. When tachycardia - propranolol (w / w).

special instructions

Caution is needed when kidney function and liver, hyperthyroidism, coronary artery disease, heart failure, arrhythmias, hypertension, prostate cancer, hiatal hernia.

Storage preparation

The temperature is not above 30 ° C.

Keep out of the reach of children.

Shelf-life

3 years.

Do not use beyond the expiration date printed on the package.

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