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Instruction for use: Dopanol
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Trade name of the drug – Dopanol
ATX code C02AB02 methyldopa (racemic mixture)
Pharmacotherapeutic group: Alpha-adrenoceptor agonists
The nosological classification (ICD-10)
I10 Essential (primary) hypertension
Hypertension, Arterial hypertension, Arterial hypertension crisis course, Essential Hypertension
Primary hypertension, Arterial hypertension, complications of diabetes, hypertension, The sudden increase in blood pressure, Hypertensive disorders of blood circulation, hypertensive condition, hypertensive crises, hypertension, arterial Hypertension, malignant Hypertension, Hypertonic disease, Hypertensive crisis, Hypertension, accelerated hypertension, malignant hypertension, The aggravation of hypertensive disease, Transient hypertension, Isolated systolic hypertension
I15 Secondary hypertension
Arterial hypertension, complications of diabetes, hypertension, The sudden rise in blood pressure, Hypertensive disorders of blood circulation, hypertensive condition, hypertensive crises, hypertension, arterial hypertension, malignant hypertension, Hypertensive crisis, Hypertension, accelerated hypertension, malignant hypertension, hypertensive crisis, The aggravation of hypertensive disease, Transient hypertension, hypertension, Arterial hypertension, Arterial hypertension crisis course, renovascular hypertension, symptomatic hypertension, renal hypertension, Renovascular hypertension, Symptomatic hypertension
Composition
1 tablet contains 250 mg of methyldopa; in multiples of 50 pcs.
Pharmacological Properties of DopanolPharmachologic effect
hypotensive, simpatoliticheskoe.
Reduces the activity of renin in the blood plasma.
Pharmacokinetics
GI absorption of about 50%, Cmax - after 2-6 hours (corresponds to the maximum hypertensive effect) duration - 24 hours.
Indications for Dopanol
Hypertension.
Contraindications for Dopanol
Hypersensitivity, depression, hepatitis, pheochromocytoma, hemolytic anemia.
Side effect of Dopanol
CNS depression (sedation, headache, dizziness), orthostatic hypotension, bradycardia, edema, dry mouth, diarrhea disorders (nausea, vomiting, bloating, diarrhea, constipation), gynecomastia, abnormal liver function, potency, hemolytic anemia, increased aminotransferase levels , fever, allergic reactions.
Dosage and Administration
Inside of 250 mg 2-3 times daily (for the first two days), then the daily dose can be increased or (rarely) reduce 250-500 mg; As a rule, an additional dose is administered in the evening; the usual daily dose of 1-2 g
Babies initially - 10 mg / kg (max 65 mg / kg) per day in 2-4 reception.
Storage conditions of Dopanol
Keep out of the reach of children.
Shelf life of Dopanol
3 years.
Do not use beyond the expiration date printed on the package.
