Instruction for use: Ditamin

Dosage form: Injection; Oral solution; Retard tablets

Active substance: Dihydroergotamine*

ATX

N02CA01 Dihydroergotamine

Pharmacological groups:

Alpha-blockers

Serotonergic agents

The nosological classification (ICD-10)

G43 Migraine: The pain of migraine; Migraine; hemiplegic migraine; Migraine headache; A migraine attack; Continuous headache; hemicranias

I95.1 Orthostatic hypotension: Idiopathic orthostatic hypotension; Orthostatic hypotension; orthostatic syndrome; Reactions by type asimpatikotonii

R51 Headache: pain in the head; cephalgia; Pain in sinusitis; Pain in the neck; Pain headache; Headache vasomotor origin; Headache vasomotor origin; Headache with vasomotor disturbances; Headache; Neurological Headache; Continuous headache

Composition and release form

1 ampoule with 1 ml solution for injection contains dihydroergotamine mesylate 1 mg; In the package 50 pcs.

1 ml solution for oral administration (20 drops) - 2 mg; In bottles of 30 ml.

1 tablet retard - 2.5 mg; In a blister 10 pcs., In the package 2 blisters.

Pharmachologic effect

Mode of action - vasodilator.

It blocks alpha1 and alpha2-adrenergic receptors of vessels, causing their expansion, slightly increases the tone of veins.

Indication of the drug Ditamin

Migraine, headache of vasomotor origin, orthostatic hypotension.

Contraindications

Hypersensitivity, coronary artery insufficiency, angina pectoris, myocardial infarction, arterial hypertension, intermittent claudication, sepsis, shock, hepatic-renal insufficiency.

Application in pregnancy and breastfeeding

Contraindicated in pregnancy. Lactating women should stop breastfeeding during the treatment period.

Side effects

Nausea, vomiting, muscle weakness, tingling in limb muscles, myalgia, angina, bradycardia or tachycardia, dizziness, swelling, itching; Rarely - ischemia of fingers and toes (gangrene), confusion, convulsions, hemiplegia.

Dosing and Administration

Inside and parenteral. Migraine, for arresting an attack (as soon as possible), in / m or s / c - 1-3 ampoules or IV / ml, the total weekly dose - no more than 6 ml; For prophylaxis - 25 drops or 1 table. 2-3 times a day (maximum dose - up to 10 mg / day) for several weeks. Orthostatic hypotension - 25 drops (1 table) in the morning and 50 drops or 2 tablets. In the evening, for 2 weeks.

Storage conditions of the drug Ditamin

In dry, the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life of the drug Ditamin

5 years.

Do not use after the expiry date printed on the package.