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DR. DOPING

Instructions

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Instruction for use: Diphenyltropine (Diphenyltropinum)

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Chemical name

Tropinic ester of diphenylacetic acid (as hydrochloride)

Pharmacological group

M-, n-anticholinergics

Nosological classification (ICD-10)

G20 Parkinson's disease

Tremor paralysis, Idiopathic Parkinsonism, Parkinson's disease, Symptomatic Parkinsonism

G21 Secondary parkinsonism

Parkinson's Drug, Parkinsonism, symptomatic Parkinsonism, The lesions of the extrapyramidal system, Parkinson's syndrome

J45 Asthma

Asthma physical effort, status asthmaticus, Bronchial asthma, Asthma lung flow, Bronchial asthma with obstruction of sputum discharge, Bronchial asthma heavy currents, Bronchial asthma physical effort, hypersecretory asthma, Hormone-dependent form of bronchial asthma, Relief of asthma attacks in bronchial asthma, Non-allergic asthma, nocturnal asthma, Exacerbation of asthma, Asthma attacks, Endogenous forms of asthma, Night asthma, Cough with bronchial asthma

K25 Gastric ulcer

Helicobacter pylori, Pain syndrome in gastric ulcer, Pain syndrome in gastric ulcer and duodenal ulcer, Inflammation of the gastric mucosa, Inflammation of the gastrointestinal mucosa, Benign gastric ulcer, The disease of the stomach and duodenum, asotsiirovannoe with Helicobacter pylori, Aggravation gastroduodenita on the background of peptic ulcer, Exacerbation of peptic ulcer, The aggravation of gastric ulcer, The organic gastrointestinal disease, Peptic ulcer of the stomach and duodenum, Postoperative gastric ulcer, Recurrent ulcers, Symptomatic gastric ulcers, Chronic inflammatory disease of the upper gastrointestinal tract, associated with Helicobacter pylori, Helicobacter pylori eradication, Erosive and ulcerative lesions of the stomach, Erosive lesions of the stomach, The erosion of the gastric mucosa, Peptic ulcer disease, Stomach ulcer, Gastric lesion, Ulcerative lesions of the stomach, Symptomatic ulcers of the stomach and duodenum

K26 Duodenal Ulcer

Pain with duodenal ulcer, Pain syndrome in gastric ulcer and duodenal ulcer, The disease of the stomach and duodenum, asotsiirovannoe with Helicobacter pylori, Exacerbation of peptic ulcer, The worsening of duodenal ulcer, Peptic ulcer of the stomach and duodenum, Relapse of duodenal ulcers, Symptomatic ulcers of the stomach and duodenum, Helicobacter pylori eradication, Erosive and ulcerative lesions of the duodenum, Erosive-ulcerative lesions of duodenal ulcers associated with Helicobacter pylori, Erosive lesions of the duodenum, Duodenal ulcer, Ulcerative lesions of the duodenum]

O60 Premature birth

Pregnancy prematurity, The birth premature, Preterm labor pains, Premature contractions prehospital, Immobilization of the uterus before the cesarean section, Immobilization of the uterus, Acute tocolysis, Threatening premature labor, Premature discharge of water, Preventing premature births, The threat of premature birth

R10.4 Other and unspecified abdominal pain

Abdominal pain, Gastrointestinal spasm, intestinal colic, Colic in infants, The feeling of fullness, Resi abdominal, Spasm of smooth muscle in diseases of the digestive tract, The spasm of the biliary tract, Biliary tract spasm, enterospasm, Spasm of the digestive tract, Spasms of the digestive tract smooth muscle, stomach Cramps, gastrointestinal spasms, Spastic condition of the gastrointestinal tract, intestinal tenesmus, Feeling of fullness, Baby colic

R25.8.0 * hyperkinesias

hyperkinesia rheumatoid; hyperkinesia trochaic; Hyperkinesia central origin; hyperkinesia; Social tremor.

T60.0 Toxic effect of organophosphorus and carbamate insecticides

Poisoning by organophosphorus compounds, Intoxication with organophosphorus compounds, Poisoning with organophosphorus compounds, Acute intoxication with organophosphorus compounds

Code CAS 6878-98-4

Characteristics

White or white with a weak creamy shade of crystalline powder. Easily soluble in water and alcohol.

Pharmacology

The pharmacological action is antiparkinsonian, spasmolytic.

The peripheral action is due to the blockade of predominantly m-holinoretseptorov membranes of effector cells located in the region of the endings of postganglionic cholinergic (parasympathetic) fibers, which prevents interaction with them of the mediator acetylcholine: relaxes smooth muscles, decreases secretion, dilates the pupil, increases heart rate. Antiparkinsonian activity is manifested by inhibition of central m-cholinergic structures and suppression of stimulating cholinergic effect on basal ganglia. Stronger inhibits central cholinergic systems and to a lesser extent affects peripheral cholinergic receptors. It also has ganglion-blocking and antispasmodic properties. Acting on the central cholinergic system, reduces motor impairment associated with the lesion of the extrapyramidal system.

Indications

Parkinson's disease, Parkinson's disease, extrapyramidal disorders (spastic paralysis, stiffness, hyperkinesis, Little's disease), spasm of smooth muscles of internal organs, spastic constipation, peptic ulcer of stomach and duodenum, bronchial asthma, bradycardia caused by increased vagal tone, threat of premature birth, Intoxication with organophosphorus compounds.

Contraindications

Hypersensitivity, glaucoma, atrial fibrillation, ciliary tachyarrhythmia, urinary retention.

Restrictions on the use

Diseases of the liver, kidney, heart, hypertension, severe atherosclerosis.

Side effects of the substance Diphenyltropine

Hyposalivation, dyspepsia, constipation, paralytic ileus, urinary retention, pupil dilated, accommodation paralysis, tachycardia, headache, dizziness, general weakness, delirium, hallucinations, allergic reactions.

Interaction

Strengthens the parasympatolytic effects of tricyclic antidepressants, violates the absorption of levodopa, shows antagonism with beta-blockers.

Overdose

Symptoms: disorders of the central nervous system (excitation, hallucinations), dry mucous membranes and skin, dilated pupils, urinary retention, tachycardia, increased intraocular pressure, increased body temperature.

Routes of administration

Inside, after a meal.

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