Instruction for use: Difen

Active substance Diclofenac

ATX Code M01AB05 Diclofenac

Pharmacological group

NSAIDs - Acetic acid derivatives and related compounds

Nosological classification (ICD-10)

M00-M25 Arthropathy

M05 Seropositive rheumatoid arthritis

Rheumatoid arthritis seropositive

M10 Gout

Exacerbation of gout, Acute articular attack with gout, Acute gouty attack, Gouty attack, Recurrent gout attacks, Chronic gout

M15-M19 Osteoarthritis

M42 Osteochondrosis

Pain in spinal osteochondrosis, Cervical osteochondrosis, Radicular syndrome in osteochondrosis, intervertebral osteochondrosis, osteochondrosis, Osteochondrosis with radicular syndrome, Osteocondritis of the spine

M45 Ankylosing spondylitis

Ankylosing spondylarthrosis, Marie-Strumpel disease, Ankylosing spondylitis, Pain syndrome in acute inflammatory diseases of the musculoskeletal system, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Bechterew's disease, Ankylosing spondylitis, Diseases of the spinal column, Rheumatic spondylitis, Bechterew-Marie-Strumpel disease

M79.0 Other unspecified rheumatism

Degenerative rheumatic disease, Degenerative and rheumatic diseases of the tendons, Degenerative rheumatic diseases, Localized forms of rheumatism of soft tissues, Rheumatism, Rheumatism with a pronounced allergic component, Rheumatism of the articular and extraarticular, Rheumatic attack, Rheumatic complaints, Rheumatic diseases, Rheumatic disease of the spine, Relapses of rheumatism, Articular and extra-articular rheumatism, Articular and muscular rheumatism, Articular rheumatism, Articular syndrome with rheumatism, Chronic rheumatic pain, Chronic articular rheumatism, Rheumatoid diseases, Rheumatic diseases of the intervertebral disc

N70 Salpingitis and oophoritis

Adnexitis, Inflammatory diseases of female genitalia, Inflammatory diseases of female genital organs, Infection of the genitals, Oophoritis, Acute adnexitis, Salpingitis, Salpingo-oophoritis, Chronic inflammatory diseases of the ovaries, Inflammation of the ovaries

N71 Inflammatory diseases of the uterus, except the cervix

Intrauterine infections, Inflammatory diseases of female genitalia, Inflammatory diseases of female genital organs, Infection of the genitals, Chronic endometriometritis, Chronic inflammatory disease of the uterus, Endometritis, Endometriometry

N73.2 Parametritis and pelvic cellulitis, unspecified

Infections of pelvic fat, Pelvic cellulite, Parametritis, Pelvic cellulite

N76 Other inflammatory diseases of the vagina and vulva

Atrofic vulvovaginitis, Vulvovaginitis bacterial, Vulvovaginitis estrogen-deficient, Bacterial vaginosis, Vaginitis, Vaginitis bacterial, Inflammatory diseases of the vagina and vulva, Inflammatory diseases of female genitalia, Inflammatory diseases of female genital organs, Vulvit, Vulvovaginitis, Gardnerella, Fungal vulvovaginitis in girls and virgins, Infection of the vagina, Infection of the genitals, Colpitis, Violation of purity of the vaginal secretion, Nonspecific cervicovaginitis, Nonspecific vulvitis, Nonspecific vulvovaginitis, Nonspecific colpitis, Recurrent nonspecific bacterial vaginosis, Senylic coverings, Mixed Colpus, Chronic vaginitis, Vulvovaginal infections, Bacterial vaginitis, Mixed vaginal infections

T08-T14 Injuries to unspecified part of trunk, limb or body region

Composition and form of release

1 tablet with enteric coating contains diclofenac sodium 50 mg, in a blister pack 10 pcs.

1 ampoule with 3 ml solution for injection - 75 mg.

pharmachologic effect

Pharmacological action - anti-inflammatory, antipyretic, analgesic.

indications

Inflammatory and degenerative forms of rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, spondyloarthritis, painful spinal injuries, extra-articular rheumatism, acute gout attacks, postoperative and post-traumatic pain conditions, pain after dental interventions, painful inflammatory gynecological diseases.

Contraindications

Peptic ulcer, hypersensitivity, "aspirin" bronchial asthma, pollinosis, age (up to 1.5 years).

Side effects

Abdominal pain, nausea, flatulence, constipation, diarrhea; fluid retention in the body, arterial hypertension, tachycardia; thrombocytopenia, anemia.

Dosing and Administration

Tablets: for adults, the initial dose is 150 mg / day (two or three meals) with meals. The maintenance dose is 100 mg / day (in several steps).

Solution for injection: for emergency relief of pain - in / m 75 mg, in the absence of effect - again after 30 minutes. It can also be administered at intervals of 12 hours, with the total daily dose not exceeding 150 mg. Transition after the first or second IM injection for oral administration provides adequate control of pain.

Usual dose in children is 2-3 mg / kg of body weight, children with a body weight of 15-30 kg - 25 mg twice a day, with a mass of more than 45 kg - 25 mg 3 times a day or 50 mg 2 times a day.

storage conditions

In a dry, cool place protected from light.

Keep out of the reach of children.

Shelf life

3 years.

Do not use after the expiry date printed on the package.