Instruction for use: Dicloran SR

Active substance Diclofenac

ATX Code M01AB05 Diclofenac

Pharmacological group

NSAIDs - Acetic acid derivatives and related compounds

Nosological classification (ICD-10)

G54.1 Disorders of lumbosacral plexus

Sciatica, Neurology radicular origin, spine Pathology, Sciatica lumbosacral, radiculoneuritis

K80.5 stones of bile duct without cholangitis or cholecystitis

Obstruction of common bile duct, Stones of the common bile duct, biliary colic, Colic liver, Hepatic colic, Cholesterol gallstones in the common bile duct

M06.9 Other specified rheumatoid arthritis

Rheumatoid arthritis,Pain syndrome in rheumatic diseases, Pain in rheumatoid arthritis, Inflammation in rheumatoid arthritis, Degenerative forms of rheumatoid arthritis, Children's rheumatoid arthritis, Exacerbation of rheumatoid arthritis, Acute articular rheumatism, Rheumatic arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatoid arthritis of active course, Rheumatoid arthritis, Rheumatoid polyarthritis, Acute rheumatoid arthritis, Acute rheumatism

M10 Gout

Exacerbation of gout, Acute articular attack with gout, Acute gouty attack, Gouty attack, Recurrent gout attacks, Chronic gout

M15-M19 Osteoarthritis

M45 Ankylosing spondylitis

Ankylosing spondylarthrosis, Marie-Strumpel disease, Ankylosing spondylitis, Pain syndrome in acute inflammatory diseases of the musculoskeletal system, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Bechterew's disease, Ankylosing spondylitis, Diseases of the spinal column, Rheumatic spondylitis, Bechterew-Marie-Strumpel disease

M47 Spondylosis

Spondyloarthrosis, spondylarthrosis, Diseases of the spinal column, spondylosis

M54.3 Sciatica

Ishialgia, Neuralgia of the sciatic nerve, Sciatic neuritis

M71 Other bursopathies

Bursitis, Bursopathy, Diseases of soft tissues, Osteoarthritis in musculo-articular diseases, Inflammatory disease of soft tissues, Subacute bursitis

M77.9 Other unspecified

Capsule, Periarthritis, Tendonitis, Tendopathy, Periarthropathy

M79.0 Other unspecified rheumatism

Degenerative rheumatic disease, Degenerative and rheumatic diseases of the tendons, Degenerative rheumatic diseases, Localized forms of rheumatism of soft tissues, Rheumatism, Rheumatism with a pronounced allergic component, Rheumatism of the articular and extraarticular, Rheumatic attack, Rheumatic complaints, Rheumatic diseases, Rheumatic disease of the spine, Relapses of rheumatism, Articular and extra-articular rheumatism, Articular and muscular rheumatism, Articular rheumatism, Articular syndrome with rheumatism, Chronic rheumatic pain, Chronic articular rheumatism, Rheumatoid diseases, Rheumatic diseases of the intervertebral disc

N23 Renal colic unspecified

Pain in renal colic, Pain smooth muscle spasm, Pain spasm of smooth muscles (renal and biliary colic, intestinal spasms, dysmenorrhea), Pain spasm of smooth muscles of internal organs, Pain spasm of smooth muscles of internal organs (kidney and biliary colic, intestinal spasms, dysmenorrhea), renal Colic, ureteral colic, Renal colic, Renal colic with urolithiasis, Kidney disease, Spasm of smooth muscle in diseases of the urinary system, The spasm of the urinary tract, The spasm of the ureter, The spasm of the ureters, Spasms of the urinary tract, Spasms of the urinary tract

N70 Salpingitis and oophoritis

Adnexitis, Inflammatory diseases of female genitalia, Inflammatory diseases of female genital organs, Infection of the genitals, Oophoritis, Acute adnexitis, Salpingitis, Salpingo-oophoritis, Chronic inflammatory diseases of the ovaries, Inflammation of the ovaries

N71 Inflammatory diseases of the uterus, except the cervix

Intrauterine infections, Inflammatory diseases of female genitalia, Inflammatory diseases of female genital organs, Infection of the genitals, Chronic endometriometritis, Chronic inflammatory disease of the uterus, Endometritis, Endometriometry

N73.2 Parametritis and pelvic cellulitis, unspecified

Infections of pelvic fat, Pelvic cellulite, Parametritis, Pelvic cellulite

N76 Other inflammatory diseases of the vagina and vulva

Atrofic vulvovaginitis, Vulvovaginitis bacterial, Vulvovaginitis estrogen-deficient, Bacterial vaginosis, Vaginitis, Vaginitis bacterial, Inflammatory diseases of the vagina and vulva, Inflammatory diseases of female genitalia, Inflammatory diseases of female genital organs, Vulvit, Vulvovaginitis, Gardnerella, Fungal vulvovaginitis in girls and virgins, Infection of the vagina, Infection of the genitals, Colpitis, Violation of purity of the vaginal secretion, Nonspecific cervicovaginitis, Nonspecific vulvitis, Nonspecific vulvovaginitis, Nonspecific colpitis, Recurrent nonspecific bacterial vaginosis, Senylic coverings, Mixed Colpus, Chronic vaginitis, Vulvovaginal infections, Bacterial vaginitis, Mixed vaginal infections

R10.4 Other and unspecified abdominal pain

Abdominal pain, Gastrointestinal spasm, intestinal colic, Colic in infants, The feeling of fullness, Resi abdominal, Spasm of smooth muscle in diseases of the digestive tract, The spasm of the biliary tract, Biliary tract spasm, enterospasm, Spasm of the digestive tract, Spasms of the digestive tract smooth muscle, stomach Cramps, gastrointestinal spasms, Spastic condition of the gastrointestinal tract, intestinal tenesmus, Feeling of fullness, Baby colic

R52 Pain, not elsewhere classified

Pain syndrome of radicular origin, Pain syndrome of small and medium intensity of different genesis, Pain syndrome after orthopedic surgery, Pain syndrome in superficial pathological processes, Radicular pain in the background of osteochondrosis of the spine, Radicular pain syndrome, Pleural pain, Chronic pain

R52.0 Acute pain

Acute pain syndrome, Acute pain syndrome with osteoarthritis, Acute pain syndrome of traumatic origin, Severe pain of a neurogenic nature, Severe pain, Pain syndrome at delivery

R68.8.0 * Inflammatory syndrome

Painful syndrome of inflammatory genesis, Pain syndrome with inflammation of non-rheumatic nature, Pain syndrome with inflammatory lesions of the peripheral nervous system, Painful inflammation of the shoulder joint, Painful inflammation after trauma or surgery, Painful inflammation after surgery, Painful hemorrhoids, Inflammation of the tympanic membrane, Inflammation of the larynx, Inflammation of the gums, Inflammation of cellulose, Inflammation of lymph nodes, Tonsillitis, Inflammation of muscles, Inflammation of soft tissues, Inflammation of the mouth, Inflammation after surgery and trauma, Inflammation after orthopedic surgery, Inflammation after trauma, Inflammation in rheumatoid arthritis, Inflammation of the middle ear, Inflammatory gum disease, Inflammatory diseases of the eyelids, Inflammatory eye diseases, Inflammatory swelling of soft tissues, Inflammatory processes, Inflammatory processes after surgical interventions, Inflammatory process, Inflammatory Syndrome, Inflammatory syndrome of non-rheumatic origin, Inflammatory syndrome after surgery, Purulent infections, Infringements of function of a liver of an inflammatory etiology, Acute inflammation of the musculoskeletal tissue, Pre-inflammatory soft tissue inflammation

Composition and form of release

1 ml of solution for injection contains diclofenac sodium 75 mg; in ampoules of 3 ml, in a box of 5 or 25 ampoules.

1 g of gel for external use - diclofenac 10 mg (in the form of diethylamine); in tubes of 20 grams, in a box of 1 tube.

1 tablet, coated with enteric coating, contains diclofenac sodium 50 mg; in a contour acheikova packing 10 pcs., in a box 2 or 10 packings.

1 tablet, coated with a shell, prolonged action - 100 mg; in a contour acheikova packing 10 pcs., in a box 2 or 10 packings.

pharmachologic effect

Pharmacological action - anti-inflammatory, antipyretic, antiaggregational, analgesic.

Indications

Inflammatory and degenerative diseases of the musculoskeletal system (rheumatoid arthritis, ankylosing spondylitis, osteoarthrosis, spondylarthrosis, etc.), rheumatic diseases of the periarticular soft tissues, acute gouty arthritis, pain in the spine, pain and inflammation syndrome after surgery, gynecological diseases, trauma , renal or biliary colic.

Contraindications

Hypersensitivity, bronchospasm, hives, rhinitis associated with the use of NSAIDs in history; erosive and ulcerative lesions of the gastrointestinal tract in the stage of exacerbation; violation of hematopoiesis of unknown origin, pregnancy, breast-feeding, age to 18 years.

pregnancy and lactation

Contraindicated in pregnancy. For the duration of treatment, breastfeeding should be discontinued.

Side effects

From the nervous system and sensory organs: headache, dizziness, increased fatigue; in rare cases - a noise in the ears, irritability, sleep disturbance, anxiety, depression, mental disorders, convulsions, blurred vision, diplopia.

From the cardiovascular system and blood (blood, gemostaz): in some cases - thrombocytopenia, leukopenia, agranulocytosis, anemia; in isolated cases, pain in the chest, tachycardia, increased blood pressure.

On the part of the intestine: pain and spasms in the epigastrium, flatulence, a decrease in appetite, a violation of liver function, including hepatitis; rarely - erosive and ulcerative lesions with bleeding and perforation, aphthous stomatitis, esophagitis; in some cases - nonspecific ulcerative colitis, Crohn's disease.

From the genitourinary system: rarely - swelling; in some cases - hematuria, proteinuria, interstitial nephritis, acute renal failure, nephrotic syndrome.

From the skin: skin rash, hives, bullous rashes, eczema, Stevens-Johnson syndrome, Lyell's syndrome, erythroderma, alopecia, photosensitivity.

Other: compaction, in some cases - abscess or necrosis at the injection site, redness, burning sensation or tingling with topical application; rarely - attacks of bronchial asthma, systemic allergic reactions.

Dosing and Administration

In / m, inside, topically. In / m deep into the muscle at a dose of 75 mg / day (in severe cases, as an exception, 75 mg twice a day with an interval of several hours) no more than 2 days, then switch to oral intake. Inside, not liquid, with a sufficient amount of fluid, preferably before meals (with increased sensitivity of the stomach allowed to take at the end of the meal or after eating), in a daily dose of 100-150 mg in 2-3 divided doses.

Locally, apply a strip of gel the size of a cherry or hazelnut to intact skin over a painful patch and lightly rub, 3-4 times a day.

storage Conditions

In the dark place at a temperature of no higher than 30 ° C.

Keep out of the reach of children.

Shelf life

solution for intramuscular injection 75 mg / 3 ml - 2.5 years.

tablets, coated with enteric coating 50 mg - 3 years.

tablets prolonged action, coated with 100 mg - 3 years.

gel for external use 1% - 3 years.

Do not use after the expiry date printed on the package