Instruction for use: Dexona
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Active substance Dexamethasone
ATX code H02AB02 Dexamethasone
Pharmacological group
Glucocorticosteroids in combinations
Nosological classification (ICD-10)
G93.6 Edema of the brain
Intraoperative cerebral edema, Cerebral edema, Post-traumatic swelling of the brain, Brain edema associated with radiation therapy, Brain edema associated with head trauma, Post-traumatic cerebral edema, Edema of the brain in poisoning
I00 Rheumatic fever without mention of cardiac involvement
Acute rheumatism, Rheumatic arthritis acute, Rheumatism is active, Rheumatic fever, Acute attack of rheumatic joint disease
I01 Rheumatic fever with involvement of the heart
Rheumatic carditis acute
J98.8.0 * Bronchospasm
Bronchospasm in bronchial asthma, Bronchospasm when exposed to an allergen, bronchospastic reactions, bronchospastic status, bronhospastichesky syndrome, Diseases accompanied by bronchospastic syndrome, reversible bronchospasm, spasmodic cough
L10 Pemphigus [pemphigus]
Benign pemphigoid of mucous membranes, Bubble dermatosis, Pemphigus, Dermatitis, vesicular, Benign pemphigus, Ordinary pemphigus, Pemphigus, Bubble dermatitis, Family benign pemphigus Hailey-Hailey
T78.2 Anaphylactic shock, unspecified
Anaphylactic shock, Anaphylactoid reaction, Anaphylactic shock, Anaphylactic reactions, Anaphylactic shock to drugs
Composition and form of release
1 tablet contains dexamethasone 0.5 mg; In contour non-jawed packaging 10 pcs.
1 ml solution for injection - dexamethasone sodium phosphate 4 mg; In bottles of 2 ml, in the outline of the cell 6 bottles.
Eye / ear drops contain dexamethasone sodium phosphate 0.1%, neomycin sulfate 0.5%, benzalkonium chloride 0.02%; In bottles of dark glass to 5 ml complete with a dropper, in a cardboard bundle 1 bottle.
pharmachologic effect
Pharmacological action - anti-inflammatory.
indications
Tablets: rheumatoid arthritis, allergic reactions, bronchial asthma, dermatological diseases, acute ulcerative colitis, rheumatic fever, disseminated lupus erythematosus, nephrotic syndrome, malignant diseases.
Solution for injection: anaphylactic shock, cerebral edema, bronchospasm, pemphigus.
Eye / ear drops: allergic and inflammatory diseases (including microbial) of the eye and ears: conjunctivitis, herpes zoster, otitis, iridocyclitis, sympathetic ophthalmia, scleritis, allergic blepharitis.
Contraindications
Tablets, solution for injection: systemic fungal and viral infections.
Eye / ear drops: hypersensitivity, tuberculosis of the eyes and ears, perforation of the tympanic membrane.
pregnancy and lactation
Perhaps, if the expected effect of therapy exceeds the potential risk to the fetus.
Side effects
Dizziness, headache, menstrual irregularities, muscle weakness, sodium retention, hypertension; Drops: cataract, glaucoma, secondary eye infections.
Dosing and Administration
Tablets: Inside, 3 mg / day (up to 4-6 mg / day). The maintenance dose is 0.5-1 mg / day in 2-4 admission.
Solution for injection: iv slowly (4-5 min), in / m, iv infusion - 1-5 ml (4-20 mg) 3-4 times a day.
Drops of the eye / ear: 1-2 drops 3-4 times a day in the eye, 3-4 drops in the affected ear 2-3 times a day.
Precautionary measures
With caution appoint for peptic ulcer of the stomach and duodenum.
storage conditions
At a temperature of 15-30 ° C.
Keep out of the reach of children.
Shelf life
Tablets 0.5 mg - 4 years.
Drops eye and ear - 3 years.
Injection for 4 mg / ml - 3 years.
Do not use after the expiry date printed on the package.