Instruction for use: Clioquinol + Flumetasone (Cliochinolum + Flumethasonum)

Pharmacological group

Glucocorticosteroids in combinations

Pharmacotherapy

Combined drug; Has anti-inflammatory, anti-edematous, anti-allergic, antifungal and antimicrobial effect. Flumethasone - GCS (glucocorticosteroids); Inhibits the release of inflammatory mediators; When exposed to the skin, there is a warning of the edge accumulation of neutrophils, which leads to a decrease in inflammatory exudate and production of cytokines, inhibition of migration of macrophages, a reduction in infiltration and granulation. Clioquinol has antimicrobial bacteriostatic and antifungal action, is active against a wide range of microorganisms, fungi and gram-positive bacteria (staphylococci). With regard to gram-negative bacteria, it is ineffective. When used as a paste, it has a drying effect when the inflammatory processes are wetting, has a cooling effect, is well fixed by the skin. Ointment has a water repellent effect (forms a protective film, protecting the skin from the effects of external moisture). Due to the presence of fat-suppressing properties, ointment is preferred for the treatment of patients with dry and thin skin. The cream containing the combination also has a cooling effect.

Indications

Eczema, atopic dermatitis, diffuse neurodermatitis, seborrheic dermatitis, psoriasis, incl. The scalp (especially dry plaques); Dermatomycosis, actinomycosis, blastomycosis, sporotrichosis; Diaper rash, multiforme exudative erythema; Erythroderma; Simple chronic lichen (limited neurodermatitis); Impetigo, secondary infections with insect bites.

Contraindications

Hypersensitivity; Cutaneous manifestations of syphilis; Tuberculosis of the skin, viral skin diseases; Trophic ulcers of the lower leg, associated with varicose veins, skin tumors (skin cancer, nevus, atheroma, melanoma, hemangioma, xanthoma, sarcoma); pregnancy.

Dosing

Outwardly. Apply a thin layer on the affected areas 2-3 times a day with the application of occlusive dressings, which are changed every 24 hours. Penetration into the deep layers of the skin under the occlusive dressing is approximately 100 more than when applied simply to the affected areas. Occlusive bandage is contraindicated in case of skin infection.

Side effect

Burning, itching, steroid acne; Stria, dry skin, folliculitis. With long-term use - skin atrophy, local hirsutism, telangiectasia, purpura, pigmentation disorders; When applied to large surfaces, systemic manifestations are possible (gastritis, ulceration of the gastrointestinal mucosa (gastrointestinal tract)).