Instruction for use: Carbo activatus

Active substance: Activated charcoal

ATX code A07BA01 Activated charcoal

Pharmacological group

Detoxifying agents, including antidotes

Adsorbents

Dosage form

Pills

Composition

One tablet contains:

Active substance:

Activated carbon - 250 mg.

Excipient:

Potato starch is 47 mg.

Description of dosage form

Tablets of black color, flat-cylindrical with a facet or with a facet and a risk, slightly rough.

Pharmacological group

Enterosorbent

Pharmacodynamics

It has enterosorbent, detoxifying and anti-diarrhea action. Refers to a group of polyvalent physicochemical antidotes, has a large surface activity. Adsorbs poisons and toxins from the gastrointestinal tract to their absorption, including alkaloids, glycosides, barbiturates and other sleeping pills and narcotics, heavy metal salts, toxins of bacterial, plant, animal origin, phenol derivatives, hydrocyanic acid, sulfonamides, gases. The drug adsorbs also the excess of some metabolic products - bilirubin, urea, cholesterol, as well as endogenous metabolites, responsible for the development of endogenous toxicosis. It weakly adsorbs acids and alkalis (including iron salts, cyanides, malathion, methanol, ethylene glycol). It is active, as a sorbent, with hemoperfusion. Does not irritate the mucous membrane of the gastrointestinal tract.

Pharmacokinetics

It is not absorbed, does not split, is released completely through the gastrointestinal tract within 24 hours.

Indications

It is used as a detoxifying agent for exogenous and endogenous toxicoses of various nature. In the complex treatment of food poisoning, salmonellosis, dysentery. When poisoning with medicines (including psychotropic, hypnotics, narcotic drugs), alkaloids, heavy metal salts and other poisons. In diseases of the gastrointestinal tract, accompanied by dyspepsia, flatulence. With food and drug allergies. With hyperbilirubinemia (viral hepatitis and other jaundice). With hyperazotemia (renal failure). To reduce gassing in the intestine before ultrasound and X-ray examination.

Contraindications

Exacerbation of gastric ulcer and duodenal ulcer, ulcerative colitis, bleeding from the gastrointestinal tract, intestinal atony, individual drug intolerance, simultaneous administration of antitoxic drugs, the effect of which develops after absorption (methionine, etc.).

pregnancy and lactation

It is possible to use the drug during pregnancy and during breastfeeding, if the expected benefit for the mother exceeds the potential risk to the fetus and the baby. It is necessary to consult a doctor.

Dosing and Administration

Apply inwards in tablets or, after preliminary grinding, in the form of an aqueous suspension, one hour before meals and taking other medicines. The required amount of the drug is diluted in ½ cup of water.

Dosing regimen: adults are prescribed an average of 1.0-2.0 g (4-8 tablets) 3-4 times a day. The maximum single dose for adults is up to 8.0 g (16 tablets). For children, the drug is prescribed on average at a rate of 0.05 g / kg 3 times a day, depending on the body weight. The maximum single dose is up to 0.2 g / kg of body weight. The course of treatment for acute diseases - 3-5 days, with allergies and chronic diseases - up to 14 days. Repeated course 2 weeks after the doctor's recommendation.

In case of acute poisoning, treatment begins with gastric lavage, using activated carbon suspension, then 20-30 g of the drug are given inside. When flatulence is prescribed orally, 1.0-2.0 g (4-8 tablets) 3-4 times a day. The course of treatment is 3-7 days.

Side effects

Dyspepsia, constipation or diarrhea, staining the stools in a dark color. With prolonged use (more than 14 days), it is possible to reduce the absorption of vitamins, calcium and other nutrients from the gastrointestinal tract.

Overdose

To date, cases of overdose have not been documented.

Interaction

Activated charcoal reduces the effectiveness of concomitant medications, reduces the effectiveness of drugs acting on the mucous membrane of the gastrointestinal tract (including ipecacuanas and thermopsis).

special instructions

When treating intoxication, it is necessary to create an excess of activated charcoal in the stomach (before it is washed) and in the intestine (after washing the stomach). Reducing the concentration of activated carbon in the medium contributes to the desorption of the bound substance and its absorption (to prevent the resorption of the released substance, it is recommended to rinse the stomach and prescribe activated charcoal). The presence of dietary masses in the gastrointestinal tract requires administration in high doses, since the contents of the gastrointestinal tract are sorbed by activated carbon and its activity decreases. If the poisoning is caused by substances participating in enterohepatic circulation (cardiac glycosides, indomethacin, morphine and other opiates), it is necessary to use activated charcoal for several days. When using the drug for more than 10-14 days, preventive administration of vitamins and calcium preparations is necessary. It is recommended to store in a dry place separately from substances emitting gases or vapors into the atmosphere. Storage in air (especially wet) reduces sorption capacity.

Influence on ability to drive vehicles, mechanisms

The use of the drug does not affect the ability to perform potentially dangerous activities requiring increased concentration and speed of psychomotor reactions (vehicle management, work with moving mechanisms, dispatcher and operator work).

Form of issue

Tablets 250 mg.

10 or 12 tablets in a contour cell package.

10 tablets in a contoured package without a cell.

1, 2, 3, 4, 5 or 10 contour mesh packages together with instructions for use in a pack of cardboard.

Contour-free, cell-free packages together with an equal number of instructions for use in a group package.

Storage conditions

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life

2 years. Do not use after the expiration date.

Conditions of leave from pharmacies

Let go without a prescription.