Instruction for use: Agnucaston

Dosage form: Drops for ingestion; Coated tablets

Active substance: Vitex agni casti fructuum extract

Pharmacological groups:

Dopaminomimetics

The nosological classification (ICD-10)

E28.9 Ovarian dysfunction, unspecified: Support of luteal phase in spontaneous or induced menstrual cycle; Support of the luteal phase during preparation for in vitro fertilization; Secondary hypofunction of the ovaries; Reduced function of the sex glands; Disturbance in the luteal phase of the ovarian cycle; Insufficiency of the luteal phase of the cycle; Estrogen insufficiency; Incomplete maturation of the follicle

N64.4 Mastodynia: Mastalgia; Soreness of the mammary glands; Cooper's disease

N94.3 Premenstrual tension syndrome: Pronounced premenstrual syndrome; Menstrual psychosomatic disorder; Menstrual syndrome; Premenstrual tension; Premenstrual status; Premenstrual period; Premenstrual syndrome; Menstruation syndrome

N94.6 Unspecified Dysmenorrhea: Pain in menstruation; Functional disorders of the menstrual cycle; Functional disorders of the menstrual cycle; Menstrual cramps; Menstruation disorder; Pain during menstruation; Painful irregular menstruation; Algodismenorea; Algomenorea; Pain syndrome with smooth muscle spasms; Pain syndrome with smooth muscle spasms (renal and biliary colic, intestinal spasm, dysmenorrhea); Pain syndrome with spasms of smooth muscles of internal organs (renal and biliary colic, intestinal spasm, dysmenorrhea); Disalgomenorrhea; Dysmenorrhea; Dysmenorrhea (essential) (exfoliative); Menstrual disorder; Menstruation painful; Metrorrhagia; Violation of the menstrual cycle; Menstrual irregularities; Prolactin-dependent disorder of the menstrual cycle; Prolactin-dependent disorder of menstrual function; Pain syndrome with spasms of smooth muscles of internal organs; Spastic dysmenorrhea; Primary disalgomenorrhea

Composition and release form

1 tablet, coated with a shell, contains a dry extract of fruit of common vegetable (Vitex Agni casti fructus) 3,2-4,8 mg, which corresponds to 40 mg of medicinal plant material; In a contour acheive box 15 pcs., In a cardboard bundle 2 or 4 packs.

100 g drops for oral administration contain a dry extract of fruit of common vegetable (Vitex Agni casti fructus) 0,192-0,288 g, which corresponds to 2,4 g of medicinal plant material (contains 17-19 vol.% Ethanol); In bottles with a dispenser of 50 or 100 ml, in a cardboard bundle 1 bottle.

Pharmachologic effect

Mode of action - hypoprolactinemic.

Has a dopaminergic effect, inhibits the release of prolactin (eliminates hyperprolactinemia); Restores the physiological cycle of gonadotropin secretion, normalizes the menstrual cycle; Promotes the involution of changes in the mammary glands (inhibition of the formation of connective tissue, normalization of the lumen of the milk ducts) and a reduction in pain in them.

Indications for the Agnucaston

Violations of the menstrual cycle associated with malnutrition of the yellow body, premenstrual syndrome, mastodynia (mastalgia).

Contraindications

Hypersensitivity.

Application in pregnancy and breastfeeding

Contraindicated in pregnancy. For the period of treatment should stop breastfeeding.

Side effects

Psychomotor agitation, confusion, hallucinations, skin allergic reactions.

Interaction

When combined with antagonists of dopamine receptors, there is a mutual decrease in the effect.

Dosing and Administration

Inside, 40 drops or 1 table. 1 time a day in the morning (Table does not chew). Duration of treatment - at least 3 months (without interruption during menstruation). If after the completion of the treatment the complaints appear again, it is necessary to consult a doctor and continue the treatment.

Precautionary measures

In the development of weakness, depression, pain in the mammary glands, as well as in the case of menstrual irregularities, it is recommended to consult a doctor.

Drops for oral administration should not be used after successful treatment of alcoholism. It should be borne in mind that the tablets, coated with a shell, contain milk sugar (lactose), which can be the cause of stomach pain and diarrhea.

Special instructions

Shake before use. When using the bottle, keep it in a vertical position.

Storage conditions of the drug Agnucaston

In the dark place.

Keep out of the reach of children.

Shelf life of the drug Agnucaston

2 years.

Do not use after the expiry date printed on the package.