Treatment with somatropin

Recombinant somatropin is an analogue of somatotropic pituitary growth hormone, which has found its wide application in medical practice. This drug is used as an effective pathogenetic agent aimed at eliminating or suppressing the development of hormonal pathologies associated with inadequate production of endogenous STH in adults and children.

Indications for use of Somatropin

Treatment with somatropin is prescribed in the presence of the following pathologies:

• Hypophyseal nanism (a sharp lag in growth and physical development in childhood due to a deficiency of endogenous growth hormone);
• Shereshevsky-Turner syndrome (chromosomal pathology, accompanied by short stature and anomalies of physical development);
• Prader-Willi syndrome (hereditary disease, accompanied by insufficient secretion of STH);
• A pronounced growth hormone deficiency in adults (in this case, the drug is used as a drug of symptomatic therapy).

Pharmacological action of Somatropin

Treatment somatropin, exactly identical to the endogenous human growth hormone stimulates the growth of long bones, stimulates the synthesis of collagen and chondroitin sulfate, accelerates intracellular protein synthesis and increases the number and size of myocytes, hepatocytes, structural units adrenal and gonads, as well as cells of the thyroid and thymus glands. In addition to a significant increase in muscle mass and bone thickening (corollary sodium retention, potassium, phosphorus, and water in the body), this formulation exhibits a pronounced hyperglycemic action (increases in blood glucose level) and provides an anti-catabolic effect (thereby reducing fatty tissue volume).

Somatropin treatment is carried out intermittent, contributing to a more long-term preservation of sensitivity, under strict laboratory control of blood parameters. Dosage is prescribed strictly individually, taking into account the age of the patient and the nature of the disease. The duration of the therapeutic effect of 1 dose of the drug on average is 12-48 hours.

Contraindications to treatment with Somatropin

Just like any other hormonal drug, recombinant somatropin has its contraindications. Treatment with somatropin is not recommended for individual intolerance to the components of the drug, the presence of malignant tumors of any location, with acute respiratory failure, a condition after major surgical interventions on the heart and abdominal cavity, and hypothyroidism. Relative contraindications include diabetes, pregnancy and the period of breastfeeding.