Silymarin

Silymarin is the extract of thistle (Milk Thistle) containing a complex of phytoestrogenic bonds of flavonolignan. Silymarinum is a gepatoprotektor, protects a liver from influence of toxins and is used for treatment of diseases of a liver. Is a part of a complex gepato protector of Gepabene and many dietary supplements.

The beneficial influence of extract on a liver is caused silibiliny is the substance which is a part of Silymarinum (thistle). Silymarinum influences a liver in two ways: first, it strengthens cellular membranes, and secondly, promotes formation of new cells. Besides, Silymarinum has antioxidatic properties.

Silymarinum interacts with free radicals in a liver and transfers them to less toxiferous bonds, interrupting process of oxidation of lipids; interferes with further destruction of cellular structures.

Stimulates synthesis of structural and functional proteins and phospholipids in the damaged hepatocytes (due to specific stimulation of a RNA polymerase And), stabilizes cellular membranes, prevents loss of components of a cell (transaminases), accelerates regeneration of cells of a liver. Please pay attention to Ventramin.

In researches Silymarinum increased secretion of FSG and caused sterility in females of rats, and also increased the LG level and Testosteron at males in a month of reception, however in 2 months of reception the level of Testosteron of males considerably went down.

Silymarinum has estrogenic effects. Thanks to ability to activate beta estrogen receptors it can be applied to treatment of an osteoporosis.

Silipid (Silipide, the Siliphos trademark) is a complex of Silymarinum and phosphatidylcholine, has almost by 10 times larger bioavailability.

Side effects

During clinical tests on patients with a prostate cancer silibilin in a dose of 13 g/days it was well transferred. Side effects, except insignificant rising of bilirubin and ALT weren't registered. According to iGuard.org, Silymarinum causes side effects not less than in 6% of patients, the most frequent complaint - fever and inflows. Nausea and a digestive disturbance is also possible.