Pramiracetam

There are many nootropics, some are more effective in the short term, while others - in the long term. But there are some supplements that miraculous properties and effects are credited almost immediately and they last for a long time. Pramiracetam is a something shrouded in a veil of mystery, that all will certainly want to try, but can not find) almost every fan of nootropics knows about it, it manages to create an image of the ideal tablet for the mind, which does not stimulate, not relaxes - namely brain improves cognitive abilities.

Pramiracetam is a modified form of Piracetam, created in the 70s of the last century in the current Pfizer subsidiary. Now it is one of the largest pharmaceutical companies in the world, with a turnover equal to approximately 30-40% of the federal budget of Russia. Let us describe the work of Pramiracetam. You can buy Piracetam.

How does Pramiracetam act

By tradition, we will apply the methods of analysis for determining the basic principles of Pramiracetam work. Analysis - is breaking something big and complex to something more simple and clear. Therefore, to begin with a look at the molecule of the nootropic drug.

We see a clear resemblance to the molecule of Piracetam, and because they are, of course, "relatives". As a consequence, will exhibit some common features.

• 1.Pramiracetam has almost no effect on any neurotransmitters. This means that it does not violate the normal rhythm of life. No phenomena of hyperstimulation or sedation.
• 2.There is a significant effect only on 1 neurotransmitter - acetylcholine. Then a little more about it.

In studies on rats was identified gain choline uptake in the hippocampus (part of the brain responsible for memory). It is known that choline is a precursor to the neurotransmitter acetylcholine, which is released during training (it is not important, the new city you walk or compose a report). A piracetam enhances the action of acetylcholine receptors.
That's the difference! To make it clearer, imagine that you need to get into the apartment, you are standing on the staircase at the entrance, and knock on the door, but no one hears you. Piracetam will make you knock harder and make Pramiracetam call friends and crowd clatter. That's what happens in the mind between neurons and neurotransmitters.

This nootrop Pramiracetam physically increases the amount of acetylcholine, circulating between neurons.

Another study of the same rats. With regards to effects on memory. 3 groups of rats received 1st pramiracetam at a dosage of 7.5 mg / kg, 2-I at a dose of 15 mg / kg, 3-I do not get anything. Rats were placed in a maze, waiting for when it will take place, where they were waiting for goodies. Then, at regular intervals, once again put them there too. After 1 and 2 weeks there was no difference in nearly all groups were maze faster on average 60 and 65%, respectively. However, since the first week, the group that received nothing - was a few percentage points behind. On the 3rd week gap had widened to 15% and held about steady until the end of the study. The higher the dosage of just quickly reached the limit.

That is, there is reason to believe that Pramiracetam buy immediately improves memory, but only slightly, and after 3 weeks, at least rats, improve memory by 15%.

• 3.There is easy AMPA activity that is at all racetam. The AMPA-receptor - it is the 2nd main "button" for the transfer of excitation between neurons, 1st - is the NMDA-receptors. In general, with the activation of AMPA receptors in the brain signals to be faster, as a result, "fly" a larger amount of data per unit time.
• 4.Improve cerebral circulation. It promotes better delivery and utilization of oxygen in the brain.
  

Summarized as: Pramiracetam improves blood circulation, increases the absorption of choline and acetylcholine creates a greater extent than Piracetam acts on AMPA-receptors.

Course of Pramiracetam

Pramiracetam generally tolerated well, it has no serious contraindications, except for hypersensitivity to the drug, and, traditional, liver and kidneys.
Side effects are more common with piracetam. Irritability and lethargy, allergy and excitement.

Headache - this is the most probable side effect. Which can be prevented. Part of this has been said in another release later recall how.

The duration of the course of Pramiracetam - 2 months, repeat the course as 2 months. Dosage 1-1.5 grams / day. Half-life in Pramiracetam is about 5 hours, and the advisability of taking 2 times a day, such as morning and afternoon.

Take strict with food or after a meal, as the drug is fat soluble 85.2%, the highest rate among racetam, piracetam, by the way, is water soluble at 96.9%.

Effects of Pramiracetam

Improving of learning and long-term memory - it's 2 main effect Pramiracetam. If you dig on the western forums out there it is described as "piracetam on steroids." And if piracetam acted you well, pramiracetam will be even better, in theory, of course.

In the early 90's in the country of Italy conducted a study Pramiracetam on 24 healthy men. There are 2 groups, one received a placebo, the other Pramiracetam 1.2 g / day. On the 11th day, both teams entered Scopolamine hydrobromide (0.5 mg ), the so-called truth serum, which can be seen in various action movies. this substance causes a temporary disorder of memory and the person bears all that he comes to my mind, can start talking about the weather, but after 5 seconds alone pharmacology. Test solve simple tests on logic and memory. All were dull scary, but the band decided to Pramiracetam tests better.

The effect is slow, progressive way during the first 2 weeks, on the 3rd week of racing and will be plateau effect.

How can I help Pramiracetam

Chicken or quail eggs (at least 2 chicken eggs per day) will be your best friends during the reception of the course. It takes really a lot of choline, pramiracetam working with him. If the choline in the system is low - the head will hurt.

An interesting course is to Piracetam or Noopept. Do not overexert liver / kidney once again, less fast food, alcohol, more oatmeal and vegetables.

Bottom line:1. Pramiracetam - a strong nootrop of racetam group.

2. Pramiracetam powered by enhanced production of acetylcholine.

3. Effects of Pramiracetam : memory, easy learning, improving mood.

4. The course of Pramiracetam - 2 months. 1-1.5 grams / day, divided into 2 doses.

5. Be sure to take extra source of choline or choline as an additive, or the head may ache and pramiracetam will work worse. It can be combined with Piracetam or Noopept.

Good luck and see you soon)