Phenotropil: Research, real effects, effective dosages
17 May 2016
Today there will be a bit of theory and a lot of interesting data regards phenotropil. This release brings sense to put a fat point in matters of basic effects phenilpiracetam.
Research of Phenotropil
- 1.It improves intellectual and mental functions of the brain.
- 1.1.The study included three groups of healthy men. The first received placebo, the second - 100 mg phenotropil, third - 200 mg p. Testing consisted of 4 jobs determining effect on short-term memory, visual information and attention. The results showed unequivocal efficacy compared to control (the author – V.N. Malyugin).
- 1.2.For the participation of 42 people were selected, are in acute cerebral infarction. All were divided into 2 groups, and in addition to the basic treatment, the first group received Phenotropil 100 mg / day, the second - piracetam 1.6 g / d. After 10 days have seen the first results of the MMSE in the context of the "memory" and "perception", but were also taking Phenotropil improvement in attention. By the end of the experiment, repeated testing has shown improvement in the group phenotropil by 20.2%, and 15.3% piracetam (the author - GN Belskaya).
- 1.3.A group of 51 people with mild cognitive impairment was divided by 2. The first - Fenotropil - 200 mg / day, the second - piracetam 1.2 g / d. For the study were chosen such tests as: the repetition of numbers, the test is "10 words" verbal associations and others. On day 15 already observed significant differences on the initial testing. And in the final, the 30th day, a group with phenotropil showed dramatic improvement in all tests.
- For example, speech activity of patients before the study was 10.48 points conditional, after - 14.83. People with cognitive impairments easier and faster formulated phrases. Group piracetam (in the table below - "Comparison Group") showed significant improvement only in the word memory test (author - AV Gustov).
- 1.4.About 20 people aged 40-50 years, with initial manifestations of cerebral circulation insufficiency (author - Villager NV) took 30 days Phenotropil 100 mg. Results: manifestations of asthenia (a form of chronic fatigue) decreased to normal levels in accordance with the scale of MFI-20. Testing Schulte tables (when looking for a specific number of a plurality of others) recorded a reduction of the search time to 32 to 24 seconds, on average. The quality of life on the visual analogue scale improved from 62 to 74%.
- 1.5.Research on a sample of 180 people! Each subject had either chronic fatigue syndrome, or myasthenia. 67 people received Phenotropil at a dose of 200-250 mg / day, 65 people - piracetam 1.2 grams / day, and the rest (47 subjects) - placebo. It lasted as much as 4 weeks. There were short-term memory tests: a test of Luria and Schulte table. Solids: group phenotropil asthenia and fatigue decreased in 85% of the people, as piracetam reduced the same syndrome in about half. The placebo did not show a statistically significant information (author – A. Fedin).
Note: In all studies, the probability that the results were coincidental less than 5%, P <0,05, sometimes less than 1%. Submitted 5 studies, multiply all the probabilities and you will realize that it is practically impossible to refute effects phenotropil related to intellectual brain functions.
- 2.Other Effects
2.1 Adaptation to stress. At the beginning of one of the largest practices of applying a wide variety of nootropics in one study, however, in rats. Participants: Phenotropil, piracetam, Phenibutum, Pantogamum, Pyritinol. Cool huh? We studied 3 types of stress: "the emotion", "pain" and "orthostatic" (overload, for example, when you get up out of bed abruptly, dark eyes). Now, attention! The first three, starting with the first place at a painful stress: Phenibutum, Phenotropil, piracetam. These substances are better quenched with physical pain among five nootropics. Emotiogenic stress, the first three: piracetam, Phenotropil, Phenibutum. Antiorthostatic: Phenotropil, Phenibutum, Pyritinol. Just a note on the athletes, the level of cortisol in the blood was significantly lower in the group with only phenotropil compared with placebo (the author - Vladimir Akhapkina). Recall study on rats! We used different dosing and should be understood that, most likely 500 mg phenibut reduce stress stronger than piracetam 500 mg or 50 mg phenotropil.
2.2 Adaptation to hypoxia. Members - aircraft pilots and people with "earth" professions. Why so? Hypoxia - when little oxygen in the body. As you know, the brave pilots as climbers can be in conditions of low oxygen content in the time as "normal" people brings ever this skill. What created the conditions for the participants? In general, they breathed a mixture with reduced oxygen content so long as their partial pressure of oxygen in the arteries are not decreased by half. In the beginning, in the middle can breathe only 2.8 minutes, but after simultaneous reception of Phenotropil after 60 min began to breathe - 3.3. The placebo did not show such results. Moreover, in order to achieve lasting results for pilots it was only 10 sessions for "Earthlings" - 14. Placebo required to spend 18 or more (author – N.A. Razsolov).
2.3. Sport. Experiment on athletes, period - 3 days. A single dose increases efficiency by an average of 5%, compared with placebo. After 3 days there was no evidence of side effects. Improve sleep, reduce its duration. There was no effect on the hormonal profile. Phenotropil increased reserves of the adrenal cortex, indicating that paragraph 2.1. (The author – S.N. Portugal)
What else
Small doses of phenotropil are also effective! A 2004 study, duration of 4 weeks (author - VM Voloshin). Phenotropil used in doses of 12-25 mg / day, and effects such as: decrease in sleep and its quality improvement, improved memory, mood, determination, were visible to the 3rd day of admission. Even the pressure was adjusted to normal or becomes lower by 7-10 points. So it makes sense to try to take a course of 25 mg 1-2 times a day for 4 weeks.
Summary:
Checkmate for those who consider nootropics useless. Phenilpiracetam - is one of the nootropics, over which many argue. There have been studies that have proven more effective nootropics today, compared with placebo. Although there are exceptions, someone it will improve on conventional 4% then there will be hardly noticeable, but someone at all 20%. In general, Phenotropil really works!
Good luck!