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Peptides

20 Oct 2016

Peptides (Greek πεπτος — nutritious) — family of substances which molecules are constructed of the remains of α-amino acids, connected in a chain by peptide (amide) communications. These are the natural or synthetic connections containing tens, hundreds or thousands of monomeric links — amino acids. This class is very different and performs the most various regulatory functions in an organism. Within this article we will consider only those peptides which are used in sport for correction of physical indicators.

"Attention" the Turn of peptide means, including growth hormone, in the Russian Federation isn't controlled legislatively. Therefore any person can stamp the bottles, glue stickers and is free sell.

Types

Now in the market peptides which represent stimulators of the growth hormone (GH) in increasing frequency meet. The most popular peptides in bodybuilding:

- From Grelin's (GHRP) group: (create the expressed peak of concentration of GR right after introduction, regardless of time of day and availability of a somatostatin in blood.)

  • GHRP-6 and Geksarelin
  • GHRP-2
  • Ipamorelin

- From the Growth Hormone group rileasing of hormone (GHRH): (introduction in an organism causes wavy rise in concentration which will be weak in hours when natural secretion of GR is reduced at the expense of a somatostatin, and high during natural rise in concentration of GR (for example, at night). In other words GHRH strengthens secretion of GR, without breaking a natural curve.)

  • GRF(1-29) Sermorelin
  • CJC-1295
  • HGH Frag (176-191) - growth hormone fragment

Advantages

Many have questions why to use new peptide substances if there is an artificial hormone of growth? The answer is simple: peptide stimulators have several weighty advantages:

Peptides are much cheaper than growth hormone. The cost of a similar rate will be several times lower.

Various mechanisms of action and elimination half-life allow to manipulate a concentration curve, trying to obtain an optimum anabolic response.

Various impact on feeling of hunger and metabolism, allows to give preference to these or those substances.

At the moment production and distribution of peptides isn't regulated by the law therefore they bravely can be ordered in network.

Quickly and completely collapse therefore it is possible not to be afraid for drug test.

Peptides as well as it is easy to check classical GR for authenticity. For this purpose it is enough to make tests on the level of a somatotropin in plasma after entering of medicine.

Other peptides

  • Melanotan 2 - suntan preparation and strengthenings of a libido
  • Bremelanotid - strengthens sexual desire and an erection
  • Gonadorelin - stimulates testosterone secretion
  • TB500 - for treatment of injuries and restoration of joints
  • SARMs (selective modulators of androgenic receptors)
  • Growth hormone stimulators
  • Insulinopodobny factor of growth (IGF-1)
  • Mechanical factor of growth (MGF)
  • Erythropoietin
  • Peptide of a delta dream (DSIP)
  • Follistatin
  • ACE-031
  • Irisin
  • The prolonged peptides

Feedbacks of scientists

Researches show that peptides stimulators of secretion of hormones of growth (GHRP), and also other not peptide substances increasing secretion really influence production of hormone of growth.

These observations formed a basis for creation of nutritional supplements – growth hormone stimulators (for example, amino acids, pituitarny peptides, Macuna pruriens, horse beans, it is well-cared alfostserat, etc.). At the moment there are data confirming that peptides stimulators of secretion of hormones of growth and some substances of not peptide nature can increase the level of hormones of growth, and also an insulinopodobny factor of growth (IGF-1) as at rest, and during physical exercises. Nevertheless, influence of these substances on a gain of dry muscle bulk was not noticed (however this research is conducted among men and women 60 years are more senior).  You can try Phenotropil.

How to dissolve peptides and it is correct to store

Recommendations urgent for all peptides:

Solvent

The solution of peptides received by means of bacteriostatic water (water for injections with addition of benzyl alcohol), remains stable on average for 2-5 days longer, than the solution received by means of regular water for injections. If these days are for you critical, can try to create bacteriostatic water independently. Practically all laboratories use bacteriostatic water as the solvent.

Storage

The lyophilized powder is recommended to be stored in the dark dry place at a temperature about 4 °C – if it is about short (1-2 months) a period. At a temperature minus 18-20 °C powder can be stored up to several years.

Hermeticity and light

Light can destroy powder, also as well as oxygen though peptides are subject to influence of the last not to the same extent. Anyway, it isn't necessary to break hermeticity of packaging – the air which got inside will slowly lead to peptide destruction.

Freezing

Yury Bombela considers that "it is possible to freeze the received solution once (no more), but only in case he šĶ is exceeded by 8. That is, only that which is prepared by means of physical solution." The mistake of the author is in what physiological solution, also as well as water for injections has šĶ =7.

Solution storage

It is the best of all to store solution at a temperature about 2-4 °C, we will allow rise to 8 °C.

Preparation of solution

Before solution preparation temperature of a bottle should be brought to room.

It is necessary to avoid direct hit of the solvent in powder – solvent shall flow down on a bottle wall.

It isn't recommended to stir up a bottle for dissolution acceleration. It is possible to shake it slow smooth movements here and there, but it is the best of all to deliver a bottle in the refrigerator – after a while all powder will be dissolved.

Introduction is carried out on the standard equipment of subcutaneous or intramuscular injections.

Option of use

How to use Ghrp + Cjc

Divorce peptides Ghrp + Cjc regular water for injections (2 ml on each bottle)

We receive Ghrp = 5mg = 5000 mkg and cjc = 2mg = 2000 mkg, in bottles

We don't forget solutions: Ghrp, cjc, after cultivation we store in the refrigerator at a temperature from +2 to +8 degrees.

Before the use we disinfect a rubber lid and the place of a prick (alcohol). It is forbidden to mix peptides in bottles.

How it is correct to put Ghrp + Cjc.

Calculation on the approximate weight of 75 - 85 kg (for convenience we use the insulin syringe on 100 divisions)

Approximate rate for 8 weeks. But take at first not complete amount, take 5 bottles of Ghrp, and 10 bottles of Cjc. Then buy in addition. Here we pursue 2 aims, economic feasibility and we will track result (perhaps will be enough and so much since the organism can give the accelerated progress).

In one division the insulin syringe of Ghrp solution there will be 25 mkg, and Cjc in one division will be 10 mkg.

On the weight of 75 - 85 kg we take in Ghrp 300mkg/in days and Cjc — 240mkg/in days.

We divide a dosage into two acceptances (morning and evening) of Ghrp on 150 mkg and Cjc po120 mkg.

We put peptides to the area of a stomach, at an angle 45 degrees. It is possible to gather in one syringe.


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