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Mexidol. Original preparation. Ethyl methylhydroxypyridine succinate.

15 Mar 2017

Mexidol is characterized by a wide spectrum of pharmacological effects, it has cerebroprotective, nootropic, antihypoxic, anxiolytic, antistress and anticonvulsant effects, eliminates the deficiency of CNS functions during aging.

Mexidol in sports
The need for antioxidant action, including as a means of inhibiting the processes of lipid peroxidation.

Hypoxic tissue damage caused by lack of oxygen during anaerobic training.

Various marathons - improves microcirculation and rheological properties of blood, reduces platelet aggregation.

Asthenic conditions, as well as for the prevention of the development of somatic diseases under the influence of extreme factors and loads.

The impact of extreme (stressor) factors.

The consequences of acute disorders of cerebral circulation, including after transient ischemic attacks, in the phase of subcompensation as preventive courses.

Encephalopathies of various genesis (dyscirculatory, dismetabolic, posttraumatic, mixed).

Syndrome of vegetative dystonia.

The mechanism of action is associated with its antioxidant, membrane-stabilizing properties. Meksidol is an inhibitor of free radical processes, LPO, modulates the activity of antioxidant enzymes (superoxide dismutase, glutathione reductase), affects the physicochemical properties of the membrane, increases the lipid content of lipids (phosphotidylserine and phosphotidyl-inositol), reduces the viscosity of the lipid bilayer. Mexidol improves energy metabolism in the cell, which along with antioxidant action creates the basis for an antihypoxic effect. The drug has a modulating effect on the activity of membrane-bound enzymes and receptor complexes of brain cell membranes, in particular GABA-benzodiazepine and acetylcholine. He himself does not bind to these receptor structures, but changes the content of mediator monoamines and amino acids in the structures of the brain. Meksidol increases the level of dopamine and endogenous peptides, blocks the activity of serine proteinases and metalloproteases.

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