Follistatin-344
21 Oct 2016
Follistatin (Follistatin-344) (it is known also as the aktivin-connecting protein) - an autokrinny glycoprotein which is formed practically in all body tissues. Follistatin is coded by FST gene.
For the first time follistatin has been isolated from follicular liquid (from here and the name) then it has been defined that he is capable to oppress a follicle - the stimulating hormone in a hypophysis share lobby. It occurs due to linkng with protein aktiviny which in turn stimulates secretion a follicle - the stimulating hormone.
"Attention" Contrary to the occurring opinion, follistatin doesn't cause a hypertrophy of a myocardium
Value in bodybuilding
Animal experiments showed that entering of a follistatin, leads to increase in muscle bulk and force of muscles at healthy animals, and at dystrophic mice muscular pathology is exposed to the return development, even in a case with elderly individuals. Follistatin acts as a blocker of a miostatin.
Essential lack of use of a follistatin as a blocker of a miostatin is low specificity of its action as it also suppresses function of aktivin which regulate growth and differentiation of almost all types of cages, including cells of gonads, pituitarny gland and skeletal muscles.
For this reason by scientists the inhibitor of a miostatin of FS I-I derivative of a follistatin and specific to a miostatin was developed. Transgene mice, expressiruyushchy this peptide, had the increased mass and force of muscles. These results are specified the therapeutic capacity of FS I-I in case of muscular dystrophies and a sarkopeniye.
The last testing which ended in 2009 on monkeys showed that genetic regulation of level of a follistatin yeilds tangible results in muscle growth and increase in force. These data pushed scientists to clinical testing in public which according to preliminary data shall begin summer of 2010.
In 2013 Follistatin-344 was available for sale on network. The prices from retail distributors constitute about 2-3 thousand rubles for 1000 mkg. You can also like Meldonium.
Effects
- Increase in force
- Growth of muscles
- Appetite strengthening, in certain cases suppression
- Increase in working capacity
- Fat loss, due to stimulation of metabolism of brown fatty cages
Application
Sellers recommend to accept Follistatin-344 according to the scheme: 100 mkg a day, hypodermically, for 10-20 days. As a rule it is used for a set of dry muscle bulk or on drying (rapid growth to 4kh by kg in 10 days is observed), also this peptide significantly raises power indicators. Follistatin-344 is represented perspective means in powerlifting as doesn't come to light on a drug test. Reddening in the place of a prick is possible.
Side effects
Follistatin exerts direct impact on folliculogenesis therefore theoretically at women complications are possible. According to literary data of the FST plays a role in development of a polikistoz of ovaries.