Excess of Immunity

Immunologist Dr. Doping - about the body fight with infection, immune response factors and necrotic inflammation.Why increase immunity can be extremely dangerous to humans? What is autoimmunity? In some cases, an infectious agent is separated from the immune factors and how to avoid it?

When you often hear the popular expression that is necessary to raise the immune system, a professional always wants to ask, what kind of immunity you have in mind, and some of them we will improve. Everyone knows that the lack of quantitative immune response - is bad. Example of this is very simple: increased incidence of children at an early age, an increased incidence of old and classic examples of people suffering from immunodeficiency, HIV infection to congenital defects of the immune system. But here there is sometimes a strange feeling that the higher the immune system, the better it will be for the one who have to contend with adverse effects, such as infection.

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The most important factor of the immune response against intracellular parasites apparently gamma interferon. This interferon, which is produced by different cells, but primarily lymphocytes. Its main function is realized - this is the activation of macrophages, ie phagocytes cells that devour germs, but do not always know how to kill it yourself. But they help the cells that produce gamma interferon. Macrophages are activated and acquire some new properties. After that, they are able to kill the parasite.

Most often there where the infection came come phagocytes - neutrophils. This situation is very clear: such as, for example, a pain and purulent inflammation around it, purulent inflammation in the glands when streptococci cause a sore throat or tonsillitis. And this is a very quick response. There these cells come first thing fagotsetiruyut bacteria and cope with the parasite.