Buspirone

Antidepressant: Buspirone (Buspiron)

Active substance: Buspirone
Buspirone struggles with vegetative and psychic manifestations of fear. In other words, it is an anxiolytic remedy. In addition, it has a significant antidepressant effect. Compared to classical drugs of this type, it does not give a sleeping pills effect, it does not relax the muscles. It can also be said that buspirone absorbed the qualities of both antidepressants and anxiolytics. Thus, the drug has a complex effect, which allows you to deal with several problems at once.

A significant advantage of the drug is that it does not cause the slightest addiction, and after discontinuation of its use, a person does not have an abstinence syndrome.

In clinical trials it was found that buspirone favorably affects the symptoms of social phobia, one of the most common types of anxiety disorders. So, 12 weeks of application of the drug was enough to make a marked improvement reached 2/3 of the patients.

Buspirone is ideally suited for complex therapy of depressive states with the concomitant use of SSRI antidepressants (selective serotonin reuptake inhibitors). The drug not only enhances the overall antidepressant effect of such therapy, but also can prevent sexual dysfunction, which can occur as a side reaction to SSRIs.

Pharmacological action: The drug acts on a number of receptors of the brain (mainly on serotonin and dopamine receptors). The effect comes smoothly and is felt at the end of the first-second weeks of treatment. Peak effect is observed after 1 month of taking the drug.

Indications for use: Buspirone is used as a means to combat anxiety. First of all, it concerns neuroses accompanied by such unpleasant manifestations as insomnia, irritability, various somatic disorders, as well as feelings of danger, tension, anxiety and anxiety. In addition, the drug is used as a component of complex therapy for mild depressions, as well as for alcohol withdrawal (as an auxiliary therapy).

Contraindications: It should avoid taking buspirone during breastfeeding and pregnancy. The same applies to hypersensitivity, serious liver disease, kidney failure, epileptic seizures, myasthenia gravis and acute angina glaucoma. Finally, the use of this drug for people under the age of majority is prohibited.

Dosage and administration: The drug is taken orally. Start treatment with buspirone with a dosage of 15 mg / day for 3 doses. The effective dose, as a rule, is 20 - 30 mg, but go to it gradually, increasing the dosage by 5 mg every 2-3 days. The maximum daily dose is 60 mg.

Side effects: Buspirone is a safe drug in terms of lack of dependence, but can cause a number of adverse reactions of the body. This is dizziness, fatigue, nausea, headaches, tachycardia, a feeling of dry mouth, irritability, drowsiness or, conversely, arousal.