Bromantane (Ladasten) - Instructions for use, Dosage, Indications, Side Effects, Reviews

Trade name of the drug: Ladasten

Rational chemical name: N- (2-adamantyl) -N- (2-n-bromophenyl) amine. INN or grouping name: bromantane.
Dosage Form: tablet.

Ladasten (Bromantane) Composition
Each tablet contains:
Active substance: bromantane (adamantilfenilamin) - 0.05 g and 0.10 g Excipients: potato starch, microcrystalline cellulose, magnesium stearate.

Pharmacotherapeutic group: anti-asthenic means.

Ladasten (Bromantane) Pharmacodynamics
Ladasten is adamantane derivatives, a positive impact on the performance of physical and mental performance. The spectrum of action of the drug combination of activating, anxiolytic, immunostimulant actions and elements actoprotective activity. In Ladasten no hypnotic-sedative and muscle relaxant properties, the drug has no addictive potential. In its application, unlike a typical action of psychostimulants, almost no effects develop hyperstimulation and aftereffect of depletion functionality of the organism.

Ladasten (Bromantane) Therapeutic action
Ladasten in patients with asthenia and anxiety-asthenic disorders manifested from the first day of its application in the form of a distinct reduction asthenic symptoms, indicators of emotional stress, somatic-vegetative manifestations; medication helps to restore the activity and increase endurance.

Ladasten mechanism of action associated with increased release of dopamine from presynaptic terminals, blockade of its re-uptake and biosynthesis enhancement caused gene expression of tyrosine hydroxylase, as well as its modulatory effect on the GABA-benzodiazepine-hlorionoformny retseptornsh complex, eliminating decrease benzodiazepine reception, growing under stress . Ladasten enhances GABA-ergic mediation, reducing the expression of the gene controlling the synthesis of GABA transporter, carrying the reuptake of the neurotransmitter.
Ladasten toxic (LD50 in rats is greater than 10,000 mg / kg, and more than 100 times greater than the effective dose).

Ladasten (Bromantane) Pharmacokinetics
The time to maximum concentration (Tmax) was 2.4 hours, the maximum concentration (Cmax) of 363.3 ng / mL, the drug elimination half-life (T1 / 2) - 11.21 hours.

Ladasten (Bromantane) Indications
Asthenic conditions of various origins, including at somatic diseases and after infectious diseases.
Neurasthenia.

Contraindications for Ladasten (Bromantane)
Pregnancy, lactation, children under 18 years of age, hypersensitivity to the drug.

Ladasten (Bromantane) Dosing and AdministrationUsed inside, regardless of the meal. The optimal single dose -50-100 mg; DSA - 100-200 mg, distributed into 2 doses throughout the day. The drug should not be used after 16 hours of the day. The duration of a course of the drug is 2-4 weeks.

Ladasten (Bromantane) Side effects
Manifestations may include the excessive activation and sleep disorders, which do not require discontinuation of the drug, it is advisable to decrease the dose. With increased individual sensitivity to the drug may develop allergic reactions.

Ladasten (Bromantane) Overdose
With substantial overdose may develop sedation. Treatment: nonspecific detoxification therapy.

Ladasten (Bromantane) Interaction with other drugs
Ladasten reduces the hypnotic effect of thiopental sodium, does not weaken the anxiolytic effect of benzodiazepines.

Ladasten(Bromantane) Reviews

Anti-asthenic drug "Ladasten" (Bromantane) - improves memory, physical and mental performance, endurance and restores the activity. Ladasten is an anti-asthenic means. It is used in asthenic and physical conditions of different genesis, after infectious diseases and neurasthenia.

I can not share my impressions about Ladasten!

Take advised friend who knows about Bromantane from your doctor and get a good and quick effect.

Everyday hassle at work, in the vanity of transport and all kinds of squabbles home-'s constant "atmosphere" in which the accounts reside. All this contributes neither calm nor fresh mind during working hours. And also not very good to rest with constant thoughts about their problems.

He took three weeks. In just one tablet! What is even less than in the manual. Maybe it's not right, but I have noticed that many drugs act on me and in smaller doses than recommended)

The result of such and such has become much more active, but without the hustle and aggression. Falling asleep fast, quiet, I do not wake up at night with thoughts of pending matters in the afternoon, and sleep until the morning and wake up in a good calm and joyful mood! But this is not some fairy euphoria. It's more like to develop a sense of confidence that problems can be solved, the case will be made in spite of the obstacles, the idea does not jump from one to the other, at a desired concentration is increased and allows no fuss.

Maybe a little messy, but there is no excuse - I write a review for the first time)

Yes! The process of waking up in the morning has become much more pleasant! ) Just a "pop-up" from sleep, and do not jump under the Service as usual.

Thanks Ladastenu gates in general and thanks to my friend, I advise to take Bromantane. I recommend heartily to all tiredand angry, all moody and nervous!