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Biomedical future: Genes and Stem Cells

06 Dec 2016

The biologist Dr. Doping speaks about genome editing technology, clinical trials of modern medicine and the prospects of cloning.

Man is composed of individual cells. All organisms in the world consist of a cell - either of one or of several. Inside each cell has a nucleus. The nucleus contains these "worms" that are called chromosomes. Chromosome - a complex consisting of deoxyribonucleic acid, DNA, and various proteins. A DNA, in turn, is very long (in a human cell is its half meter) chemical molecule consisting of individual bases. And the order of these reasons, in fact, is the genetic code.

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Today we are able to take and cut the genetic text as it is convenient with the help of genetically engineered scissors. If we cut a normal piece of text, you can then move it to another molecule, where this genetic text was incorrect. Thereafter, a corrected DNA molecule, we can introduce a vector such as a virus. Everything that we built in it, drag it into the cells, respectively, it will go into the cage, then go down to the core, take the genetic information, this new genetic information is somehow mixed with previous genetic information. If she was wrong, she will fix it, and the cell will use the new gene. The viruses may be delivered to the person as an injection or as you contract adenovirus, aerosol, through the nose. A is another kind of gene therapy, where we can take cells from the body, in any way to manipulate them, and then deliver the gene into a culture of these cells and then transplanted back into the body. In addition, there are other viruses, non-viral delivery form. But in any case it is not necessary to be afraid of viruses. Today viruses as vectors for gene therapy are widely used throughout the world.

The market potential of reprogramming technology in 2013 was estimated around $ 200 million if the entire market - 600 million and is expected to experts in the implementation and development of reprogramming technologies, in 2015-2016 it will amount to one third of the total market use of cellular technologies in practice.. The Gurdian this year called the next revolution in human biology, and it has already begun, organelles. It's fantastic because you can take from each ear lobe fibroblasts, skin cells, grow them, and then reprogram differentiated neurospheres. But scientists from Austria went further: they began to cultivate them in a bioreactor, and it turned out that after a while there is an analogue of the human brain.

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