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Bioengineering of internal organs

06 Nov 2016

The biologist Dr. Doping tells about directions in bioengineering, ethical issues of stem cell research and the prospects for the creation of the internal organs.

Suffice it is widely believed that everything is very good in the field of bioengineering of artificial organs. And now scientists are almost easy to create any body. There is a wonderful series, which tell about the life of a non-existent American doctors, as is usual in the series. There, in particular, it describes how doctors of 3D-printers to print various organs. In fact, to this state medicine has not yet been reached, but there is a feeling of desire for something like that.

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The method, which is now very actively developed, - every year comes a lot of articles - is to take the body of the animal, such as a pig, and remove from it all the cells, simply dissolve them. Collagen is inert enough, and it will remain. Will a skeleton body that we will populate the cells, and may be interacting with some frame to restore the structure. With this work, something that works, sometimes even get a heart that can beat a bit, trying to transplant it to animals, and sometimes something even works. Still to medicine is still very far away, and I doubt very much that it may appear tomorrow. Is there any possibility to overcome this curse can not be created in an adult organism complex new bodies, a new three-dimensional organization? Apparently, in many cases - not. But if this can not be done as an adult, you can try to go back to an embryonic state. And so once there is the idea that you need to work with those cells that retain the properties and potential of embryonic stem cells.

The technology completely different way forced to take a look at what's inside the body. We have always believed that differentiation - is the way in one direction, the cells are totipotent by the state, then embryonic stem cells in a pluripotent state and then are multipotent stem cells that differentiate and die. Always in the same direction, the irreversible process. Here the process is fully converted - mature differentiated skin cells transformed by properties in the near-fetal. How to use it? Naturally, there is an idea that now we will raise some body and transplanting it - yet. But still something you can do already.


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