Antidepressants - Principle of Act, Benefits and Dangers

I tried to avoid very long threads about antidepressants, because I believe that they often do not eliminate the causes of depression. It turns out a kind of circuit: a man can not deliver any vitamins, minerals or sleep, he feels depressed, taking antidepressants. Condition improves, then it stops receiving and eventually returned to the starting point. After all, our people are not conditioned to change their lifestyle and nutrition, respectively temporary improvement. Someone may say that nootropics also give a temporary effect, it is not so: on Nootropil we usually deal with mental activities, and information experience, we received does not disappear anywhere after the course. Antidepressants do not last a lifetime improves health and mood. Before you embark on a world of pills of a bad mood, remember once and for all: "Without a change of lifestyle, without addressing the causes of depression - antidepressants do not help." This is typical for most depressions. Yes there is, difficult situations, for example, a person from birth MAO enzyme is too active, but these are rare cases and they need an individual approach of treatment with your doctor.

Look for the start of the release of the depression, if someone has not seen. It explains the causes of depression and how depression can be understood if it is an oppressive feeling or "plans for the rest broke down fucking sucks me all leave me alone!".
Also an important point. As in the famous phrase "The devil is in the details", pay attention to the details: take Vitamins normally eat and sleep, socialize with friends or make new friends, let the body to moderate exercise, set yourself goals and algorithms of their performance and you will feel yourself better !

Let's start with antidepressants, which are relatively safe that you can drink "just so":

• 1.Any supplements and medicines based on plants such as the St. John's wort. The plant is unique. Conducted many studies where the effects of this travushki compared with the mother's antidepressants, the results were such that the effectiveness of the treatment is slightly lower than using strong drugs, and often side effects as much as 3 times less! Brief principle of St. John's Wort - a light reversible inhibitor of MAO.
• 2.Adaptogens. Helps with chronic fatigue, which is often associated with symptoms of depression. This may include Rhodiola, Rhaponticum, Eleutherococcus. They are comfortable, bought a tincture, add a little bottle of water and drink throughout the day, many-sided tonic effect on the body is provided. Just some of them, such Leuzea can take a long time without any harm to the body.
• 3.Saffron. The same seasoning for food! There is evidence that taking 30 mg of extract for 8 weeks has antidepressant effects only slightly inferior to the traditional heavy antidepressants, but this supplement is contraindicated in pregnant women and can be toxic when taking more than 30 mg per day over 8 weeks.
• 4.Zinc. Useful trace elements, especially for men, because the slightly increases the concentration of testosterone. To improve the mood is already sufficient zinc 7-10 mg per day for testosterone - 25-30 mg. This additive is generally desirable to drink on a regular basis. Compared with antidepressants, zinc weaker, but has almost no side effects. Zinc is not usually sold in the form of pure metal, eg, zinc sulfate, citrate, gluconate. And especially to receive 20 mg of zinc, you need to eat 80 mg of zinc sulfate or citrate 60 mg. In general, read more on their own.

The above mentioned additives have a low incidence of side effects and contraindications. Then go heavy artillery against the project that you are currently prescribed these substances. Let us examine them solely for information.
Medications antidepressants can be classified in different ways, we consider the main groups:

• 1.SSRIs. These antidepressants to artificially increase the concentration of serotonin in the synaptic cleft, in the brain it becomes larger expense bigger decay period. For example, one molecule of serotonin from the synaptic cleft out of the conditional moment SSRIs prolong her life up to 1.5 minutes. Serotonin increases the feeling of general well-being, increases living comfort, excess leads to side effects. These antidepressants like Fluoxetine and its analogs beat strongly and sharply precisely serotonin. (Citalopram, Escitalopram, Fluoxetine, Paroxetine, Sertraline, Fevarin).
• 2.MAO inhibitors. On them was written an article, it's a bit difficult for beginners, but on his fingers to explain the biochemistry hard. MAO inhibitors essence - not only to increase the concentration of serotonin, dopamine and norepinephrine with. This is the offensive on all fronts in the fight against depression, immediately observed the greatest number of side effects. Perhaps a person has only a lack of norepinephrine and serotonin and an excessive increase in dopamine bad mood enhancing vomiting and heartbeat - one of the most innocuous side effects.
• 3.Monoamine agonists. This anti-depressants, which are structurally very similar to the neurotransmitter molecules, if they are deceiving the body, causing him to believe that this is a neurotransmitter tablets and let it decay product in the host brain. Ie life monoamines will not be extended as with MAO inhibitors and reuptake, and increases production of specific substances. (Amitriptyline, Bupropion, Citalopram, Desipramine, Fluoxetine, Fluvoxamine, Imipramine, Milnacipran, Mirtazapine, Nefazodone, Paroxetine, Reboxetine, Venlafaxine).

The first 3 groups - antidepressants is that sense as we understand them: a good mood, ease activity. But sometimes referred to antidepressants tranquilizers because they reduce the great concern, but it almost did not improve the mood of the person making the kind of vegetable. Tranquilizers - it's almost the main group of drugs in psychiatric hospitals. They act through the neurotransmitter GABA, which is the main inhibitory CNS, ie it soothes the body. Classic as tranquilizers - benzodiazepine. The powerful and ruthless, addictive and dependence, the most prominent representative of this group - Phenazepam.

Border position
Selank - antidepressant drug with nootropic activity, it consists of neuropeptides like Semaks. But if Semax orientation is in the direction of activation + nootrop then Selank - is sedation + nootrop. Quite a good drug for stress conditions.
One of the simplest and easiest of tranquilizers, antidepressants - is Phenibut, expense of the phenyl group of a moderate stimulating effect and therefore officially included in the list of nootropics. Modification of Phenibut - Baclofen, this is a heavy tranquilizer comparable Phenazepamum.

Bottom Line:

- Antidepressant use is appropriate to begin only after the prescribing physician with severe depression.

- Such things as adaptogens, zinc and saffron can try and "just so", the low incidence of side effects, but, in any case, need to read the contraindications.

- In the majority of cases to deal with depression, it is important to change something, change your lifestyle, or thinking, or antidepressants will give a temporary effect, because the cause is corrected.

Do not be sad for nothing, remember that everything is temporary! See you later!