Actovegin - cell regeneration?!

Another interesting and very popular in the CIS substance - Actovegin or hemo-derivative deproteinized calf blood. Yes, that's right, this substance - something like a processed blood of calves, which has a variety of effects on the body, including nootropic.

It is interesting as well, and that the substance in the early 2000s, the whole year was in the doping list, and applications in the US and Canada and did not allowed.

How does actovegin act?

• 1.Transport and utilization of glucose. We always have a blood glucose value is determined, the approximate rate of 3.3 to 5.5 units. When we eat - value of the blood glucose abruptly increases above normal in response thereto starts our pancreas to produce insulin, which transports the excess glucose into the cells. Actovegin partly similar to the action of insulin.
• 2.It stimulates oxygen consumption. It's a hell of an interesting point, which is peculiar to many antihypoxants, such as the same mexidol or succinic acid. What are its benefits? It is no secret that the cells need oxygen for life and is always needed, otherwise 5-10 minutes and sure death. So, there is such a parameter as maximum oxygen consumption: remember how much you run 1 km or less ran, remember how much you can work intelligently, it is to solve problems, something to count, write, in short "think hard" as a responsible exam.

At these moments, the brain or muscles, depending on what you are doing, actively consumes oxygen. And train people capable of 1.5-2 times consume more oxygen, no matter what they are trained, even brain cells. Increased oxygen consumption increases the performance of any activity. The theme is very large, it is interesting - google yourself.

• 3.Increases ATP concentration of ADP, phosphocreatine. Part of the item associated with the transport and utilization of glucose. In order not to go into the details - will have more energy. Basically, you can just eat a sugar cube, and also increase the ATP. But then again he and phosphocreatine - the perfect assistant for the myocardium, the heart muscle.
• 4.Increases Glutamate, Aspartate, GABA. Excitatory and inhibitory neurotransmitters in the brain.
• 5.It improves spatial memory and learning. The study was conducted in rats with a damaged brain ischemia. One group was administered Actovegin, the other nothing. Subsequently, memory tests were conducted in the water maze, and later evaluated the difference in the hippocampus portion of the brain responsible for memory. In the group with Actovegin remained about 2-fold more cells, but it is still 30% less than in rats with completely normal brain.

Another study of Actovegin in the elderly with mild cognitive impairment showed improvement in memory tests, the average age - 71 year sample - 30 people.

Increased activity of alpha and beta in the brain as compared with placebo, which may slightly increase attentiveness and improve mood.

• 6.It reduces acidification of human skeletal muscle. That can be useful when working on power endurance, as an example - Pulling on the maximum number of times. However, when pure aerobic load example - hour cycling - no improvements have been reported. Also there was a slight acceleration of muscle recovery during various injuries.
• 7.Possible to improve endothelial function. The endothelium - an inner layer of blood and lymph vessels, which regulates blood pressure and blood clotting. Ie possible pressure normalization.

And another interesting study a significant reduction in acne or, quite simply, acne in 54 of the 88 people. Especially noticeable was the introduction of injection, instead of tablets.

Course of Actovegin

There are some contraindications much better just to read the instructions. Side effects - allergic reactions.

This Actovegin material was used 4th ways: Actovegin pills, Actovegin ampoules for intramuscular injection, Actovegin cream for dermal and Actovegin solutions for administration via dropper.

Let us dwell on theActovegin pill: a course on the instructions or on prescription lasts 4-6 weeks, 3-6 tablets a day for 3 doses.

Just like the drag Actovegin glucose from the blood, most people are likely from this action will be nothing. For a small portion - unpleasant phenomenon when a person low blood sugar, as an example, you do not eat 15 hours or you have it initially low.

In general, it may be easy hypoglycemia: a sense of vibrating conveyor, heat and when you want to eat too. It is therefore reasonable to take after meals.

Effects of Actovegin:

In general, according to the register of medicines in Russia, located in Actovegin pharmaceutical group tissue regeneration stimulants.

It sounds fantastic, but do not expect serious effects, although research has links to more rapid wound healing, better cellular respiration, skin improvement.

Get on Actovegin possible: increased productivity (through the delivery of glucose and oxygen), more rapid recovery of the body under all adverse pieces associated with poor cellular respiration, if we say, got anything intoxication or restore balance in the braking / accelerating neurotransmitters.

Perhaps the improvement in memory after brain injury.

Actovegin Interaction:

Theoretical number This item is longer, because the manufacturer simply wrote that the drug interaction is unknown.

The first thing that caught my eye - the similarity with Mexidol and succinic acid. Only mexidol we helped better dopamine and GABA binds to the receptor, and actovegin - glutamate, GABA, aspartate.

Joint ligaments can spur the kind of normalization of neurotransmitters in the brain and excellent recovery. Interesting may be a bunch of l-theanine, it also strengthens the alpha and beta rhythms in the brain.

Bottom Line:

- Actovegin - interesting stuff with a wide range of actions.

- Works still more as a reducing agent through the delivery of oxygen and glucose, helps the heart muscle, increases glutamate and GABA.

- To take a few weeks, the dosage depends on the indication.

- The effects are almost invisible when all health is excellent, always full of energy. The condition is worse - the drug works more clearly.

- Combine can be Succinic acid, Mexidol or L-theanine.

Good luck and all the great state!