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Instruction for use: Triamcinolone (Triamcinolonum)

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Pharmacological group

Glucocorticosteroids

Nosological classification (ICD-10)

C50 Malignant neoplasm of breast

Cancer of the nipple and areola of the breast, Breast carcinoma, The hormone-dependent form of recurrent breast cancer in women in menopause, Hormone-dependent breast cancer, Disseminated breast carcinoma, Disseminated Breast Cancer, Malignant breast cancer, Malignant neoplasm of breast, Contralateral breast cancer, Locally advanced or metastatic breast cancer,Locally-distributed breast cancer, Locally-recurring breast cancer, Metastatic breast carcinoma, Metastasis of breast tumors, Metastatic breast carcinoma, Inoperable breast carcinoma, Incompatible breast cancer, Breast cancer in women with metastases, Breast cancer in men with metastases, Breast Cancer, Breast cancer in men, Mammary cancer, Breast cancer with distant metastases, Breast cancer in postmenopausal women, Breast cancer hormone-dependent, Breast cancer with local metastases, Breast cancer with metastases, Breast cancer with regional metastases,Breast cancer with metastases, Common hormone-dependent forms of breast cancer, Common Breast Cancer, Recurrent Breast Cancer, Recurrence of breast tumors, Breast cancer, Estrogen-dependent breast cancer, Estrogen-Dependent Breast Cancer, Disseminated breast cancer with overexpression of HER2, Tumors of the mammary glands

C61 Malignant neoplasm of prostate

Adenocarcinoma of the prostate, Hormone-dependent prostate cancer, Hormone-Resistant Prostate Cancer, Malignant tumor of prostate, Malignant neoplasm of prostate, Carcinoma of the prostate, Locally-distributed non-metastatic prostate cancer, Locally advanced prostate cancer, Locally spread prostate cancer, Metastatic prostatic carcinoma, Metastatic prostate cancer, Metastatic hormone-resistant prostate cancer, Non-metastatic prostate cancer, Incompatible prostate cancer, Prostate Cancer, Prostate cancer, Common prostate cancer, Testosterone-Depot Prostate Cancer

C81 Hodgkin's disease [lymphogranulomatosis]

Paltauf-Sternberg disease, The generalized form of Hodgkin's disease, Lymphogranulomatosis, Hodgkin's disease, Hodgkin's lymphoma, Hodgkin's malignant lymphoma, Hodgkin's lymphoma, Lymphoproliferative diseases, Reticulosis fibromyaloid, Pelya-Ebstein fever

C85.0 Lymphosarcoma

C91.0 Acute lymphoblastic leukemia

Recurrence of acute leukemia, Blast Crisis, Lymphoblastic leukemia, Lymphoid blast crisis, Acute lymphoblastic leukemia, Acute lymphoblastic leukemia in adults and children, Acute lymphoblastic leukemia in children, Acute lymphatic leukemia

C91.1 Chronic lymphocytic leukemia

Chronic lymphatic leukemia with tumor-like growths, B-cell CLL, B-cell chronic lymphocytic leukemia, Chronic granulocyte leukemia, Chronic leukemia, Chronic lymphoblastic leukemia, Chronic B-cell lymphocytic leukemia

C92.9 Myeloid leukemia, unspecified

Anemia in patients with myeloma, Myeloid aplasia of the bone marrow

C95 Leukemia of unspecified cell type

Acute non-lymphocytic leukemia, Leukemia undifferentiated, Undifferentiated leukemia, Non-lymphocytic leukemia, Acute leukemia in adults, Non-lymphocytic leukemia

C96 Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissues (hematoblastosis, hematosarcoma)

Hematosarcomas

D55-D59 Hemolytic anemia

D69.3 Idiopathic thrombocytopenic purpura

Werlhof's disease, Idiopathic autoimmune thrombocytopenia, Idiopathic thrombocytopenic purpura of adults, Idiopathic thrombocytopenic purpura in adults, Immune idiopathic thrombocytopenic purpura, Immune thrombocytopenia, Bleeding in patients with thrombocytopenic purpura, Evans Syndrome, Thrombocytopenic purpura, Thrombocytopenia of immune origin, Chronic idiopathic thrombocytopenic purpura, Essential thrombocytopenia, Autoimmune thrombocytopenic purpura in pregnancy, Posttransfusion purpura

D69.6 Thrombocytopenia, unspecified

Hemorrhagic diathesis of thrombocytopenic origin, Hemorrhagic syndrome of thrombocytopenic origin, Idiopathic thrombocythemia, Thrombocytopenia, May-Hegglina anomalies, Hereditary thrombocytopathies, Fever with thrombocytopenia

D70 Agranulocytosis

Agranulocytosis is hereditary, Aleicia, Aleykocytosis, Agranulocytic angina, Angina agranulocytic, Primary cytopenia

E06.3 Autoimmune thyroiditis

Autoimmune thyroiditis Hashimoto, Thyroid Bladder Lymphadenoid, Hashimoto's disease, De Kervena thyroiditis, Goiter lymphomatous, Goiter lymphocytic, Zob Hashimoto, Lymphadenoid goiter, Thyroiditis Hashimoto, Hashimoto thyroiditis, Struma Hashimoto

E27.4 Other and unspecified adrenocortical insufficiency

Hypocorticism, Hypoaldosteronism, Adrenal insufficiency, Insufficiency of the adrenal cortex, Insufficiency of the adrenal cortex, Secondary adrenocortical insufficiency, Secondary adrenal insufficiency, Secondary insufficiency of the adrenal cortex, Temporary decrease in the function of the adrenal cortex, Dysfunction of the adrenal cortex

E83.5 Disorders of calcium metabolism

Loss of calcium in bones and teeth, Replenishment of a lack of calcium, Malabsorption of calcium, Violation of calcium metabolism in the body, Violation of the calcium-phosphorus balance, Disturbance of calcium metabolism, Impaired calcium absorption, Decreased calcium absorption, Replenishment of calcium deficiency

I09.0 Rheumatic myocarditis

J30 Vasomotor and allergic rhinitis

Allergic rinopatiya, Allergic rhinosinusopathy, Allergic respiratory diseases, Allergic rhinitis, nasal allergy, Seasonal Allergic Rhinitis, Vasomotor rhinitis, Long-allergic rhinitis, Perennial allergic rhinitis, Perennial allergic rhinitis, Year-round or seasonal allergic rhinitis, Year-round allergic rhinitis nature, Rhinitis allergic vasomotor, Exacerbation of pollen allergy in the form of Syndrome rinokonyunktivalnogo, Acute allergic rhinitis, Edema of the nasal mucosa, Edema of the nasal mucosa, Swelling of the mucosa of the nasal cavity, Swelling of the nasal mucosa, Swelling of the nasal mucosa, pollen disease, Permanent allergic rhinitis, rhinoconjunctivitis, rhinosinusitis,rhinosinusopathy, Seasonal allergic rhinitis, Seasonal Allergic Rhinitis, Haymarket rhinitis, Chronic allergic rhinitis, Allergic respiratory diseases

J42 Chronic bronchitis, unspecified

recurrent bronchitis, Bronchitis asthma, wheeze bronchitis, chronic Bronchitis, Inflammatory airways disease, bronchi disease, Qatar smoker, Cough in inflammatory diseases of the lung and bronchus, Exacerbation of Chronic Bronchitis, Chronic bronchitis, Chronic obstructive pulmonary disease, Chronical bronchitis, Chronic bronchitis smokers, Chronic spastic bronchitis, allergic Bronchitis

J43 Emphysema

Interstitial emphysema, Emphysema, Chronic lung disease, Chronic obstructive pulmonary disease, Obstructive pulmonary emphysema, Chronic pulmonary emphysema, Chronic obstructive pulmonary emphysema

J45 Asthma

Asthma physical effort, status asthmaticus, Bronchial asthma, Asthma lung flow, Bronchial asthma with obstruction of sputum discharge, Bronchial asthma heavy currents, Bronchial asthma physical effort, hypersecretory asthma, Hormone-dependent form of bronchial asthma, Relief of asthma attacks in bronchial asthma, Non-allergic asthma, nocturnal asthma, Exacerbation of asthma, Asthma attacks, Endogenous forms of asthma, Night asthma, Cough with bronchial asthma

K50 Crohn's disease [regional enteritis]

Crohn's disease, Crohn's disease with fistula, Granuloma of the intestine, Granulomatous enteritis, Crohn's disease, Regional ileitis, Terminal Ileitis, Enteritis regional

K51 Ulcerative colitis

Colitis acute ulcerative, Colitis ulcerative, Ulcerative-necrotic colitis, Colitis ulcerative-hemorrhagic nonspecific, Colitis ulcerative and trophic, Colitis ulcerative idiopathic, Colitis ulcerative nonspecific, Nonspecific ulcerative colitis, Proctocolitis ulcers, Hemorrhagic purulent rectoxitis, Rectoccolitis ulcerative-hemorrhagic

L10 Pemphigus [pemphigus]

Benign pemphigoid of mucous membranes, Bubble dermatosis, Pemphigus, Dermatitis, vesicular, Benign pemphigus, Ordinary pemphigus, Pemphigus, Bubble dermatitis, Family benign pemphigus Hailey-Hailey

L13.0 Herpetitic dermatitis

Dyurling disease, Bullous herpetiform dermatitis, Duhring's herpetiform dermatitis, Dühring's dermatitis, Herpetiform dermatitis

L20 Atopic dermatitis

Itchy atopic eczema, Common neurodermatitis, Allergic skin diseases, Allergic skin diseases of non-infectious etiology, Allergic skin diseases of non-microbial etiology, Allergic skin diseases, Allergic skin lesions, Allergic manifestations on the skin, Allergic dermatitis, Allergic diathesis, Allergic itching dermatosis, Allergic Skin Disease, Allergic skin irritation, Dermatitis allergic, Atopic dermatitis, Dermatosis allergic, Diathesis exudative, Skin Allergic Disease, Skin allergic reaction to medicinal and chemical preparations, Skin reaction to medication, Skin and allergic disease, Acute eczema, Chronic atopic dermatitis, Exudative diathesis, Itching allergic dermatosis

L23 Allergic contact dermatitis

Allergic dermatitis, Purulent allergic dermatopathies, Contact allergic reaction, Contact allergic dermatitis, Photoallergic contact dermatitis

L26 Exfoliative dermatitis

Dermatitis exfoliative, Exfoliative dermatitis generalized

L28 Simple chronic lichen and prurigo

Scab, Prurigo, Bacterial prurigo, Limited prurigo with a strong lichenization, Nodular pruritis

L29.3 Anogenital pruritus, unspecified

Itching in the genital and anus, Anal itching, Anogenital itching, Genital itching, Anogenital itching, Itching of the anorectal region, Itching of the vulva, Itching of the genitals, Perianal dermatitis

L30.4 Erythematous intertrigo

Erythema of the buttocks, Dermatitis traumatic, Intertrigo, Interdigital intertrigo

L30.9 Dermatitis, unspecified

Allergic dermatoses complicated by a secondary bacterial infection, Anal eczema, Bacterial maturation, Varicose Eczema, Venous dermatitis, Inflammation of the skin, Inflammation of the skin upon contact with plants, Inflammatory Skin Diseases, Inflammatory skin reactions, Inflammatory processes of the skin, Hypostatic dermatitis, Fungal Eczema, Fungal dermatosis, Dermatitis, Dermatitis is stagnant, Dermatitis and eczema in the anal area, Dermatitis acute contact, Perianal dermatitis, Dermatosis, Dermatosis of the scalp, Dermatosis of psoriasis, Dermatosis with persistent itching, Dermatoses, Dermatoses itchy, Other itching dermatoses, Significant eczematous manifestations, Itching with, dermatoses, Itching eczema, True eczema, Skin reaction to insect bites,Skin itching with dermatosis, Constitutional eczema, Weeping eczema, Drowsing inflammatory skin disease, Dying Infectious-Inflammatory Skin Disease, Non-allergic dermatitis, Nummular eczema, Acute contact eczema, Acute inflammatory skin disease, Acute dermatosis, Acute severe dermatosis, Perianal dermatitis, Superficial dermatosis, Subacute Contact Eczema, Simple dermatitis, Occupational dermatitis, Psychogenic dermatosis, Bubble dermatitis of newborns, Pustular eruptions, Irritation and redness of the skin, Low-flammable eczema, Dry atrophic eczema, Dry eczema, Toxic dermatitis, Ear eczema like dermatitis, Chronic eczema, Chronic dermatosis, Chronic common dermatosis, Scaly papular dermatosis, Eczema, Eczema anal region, Eczema of the hands, Eczema Contact, Eczema lichenized, Eczema Nummular, Eczema acute, Eczema acute contact, Eczema subacute, Eczematous dermatitis, Eczema-like rashes, Ecome exogenous, Endogenous eczema, Gluteal dermatitis, Restricted itchy dermatitis

L40 Psoriasis

Chronic psoriasis with diffuse plaques, Generalized psoriasis, Psoriasis of the scalp, Psoriasis of the scalp, Generalized form of psoriasis, Psoriasis dermatitis, Psoriasis complicated by erythroderma, Invalidative psoriasis, Isolated psoriatic plaque, Exfoliative psoriasis, Psoriatic Erythroderma, Psoriasis with eczematosis, Hyperkeratosis in psoriasis,Inverse psoriasis,Psoriasis eczematous, Dermatosis of psoriasis, Psoriasis of the genitals, Psoriasis with lesions of hairy areas of skin, Erythrodermal psoriasis, Chronic psoriasis of the scalp, Chronic psoriasis, Ordinary psoriasis, Refractory psoriasis, Kebner phenomenon, Scaly lichen

L50 Urticaria

Idiopathic chronic urticaria, Injury Urticaria, Chronic urticaria, Hives of the newborn

L51 Erythema multiforme

Stevens-Johnson syndrome, Malignant exudative erythema, Multiforme exudative erythema, Erythema multiforme, Multiforme exudative erythema, Stevens-Johnson Syndrome, Exudative multiform erythema, Erythema is polymorphic

L56.2 Photocontact dermatitis [berloque dermatitis]

Photoallergic contact dermatitis

L63 Alopecia areata

Lupecia nesting, Nesting baldness, Nesting alopecia, Alopecia marginal alopecia, Nesting baldness, Alopecia areata, Hair loss in the form of a circle, Circumferential baldness

L90.5 Lung scars and fibrosis of the skin

Cicatricial skin lesions, Scars after burns, Scars after operations, Cicatricial states, Scarring, Skin Fibrosis, Atrophic scars after acne, Atrophic scars after furunculosis, Atrophic scars after surgery, Hypertrophic scar, Cutaneous scar after wound healing, Retracted scars after operations, Hypertrophic scars due to injuries, Hypertrophic scars after burns, Scar tissue, Retracted scars, Fresh postoperative scars, Fresh posttraumatic scars, Burn scar, Stretch marks after pregnancy, Atrophic scars

L98.9 Lesion of skin and subcutaneous tissue, unspecified

Adiponecrosis, Atonic leather, Diseases of the skin, Blister, Inflammatory disease of soft tissues, Inflammatory processes of epithelial tissues, Degenerative changes in the skin and mucous membranes, Degenerative changes in the skin and mucous membranes, Excess granulation, Thinning of the skin, Skin diseases, Maceration of the skin, Minor skin lesions, Surface crack and skin abrasion, Increased skin peeling, Skin lesion, Erosion of the skin, Lipedema, Local non-infectious processes of skin and soft tissues, Disturbance of skin structure, Dysfunction of the skin, Skin disorders

M00-M03 Infectious arthropathy Arthritis is infectious, Pyogenic arthritis, Septic arthritis, Infections of the joints

M05 Seropositive rheumatoid arthritis

Rheumatoid arthritis seropositive

M06.9 Other specified rheumatoid arthritis

Rheumatoid arthritis,Pain syndrome in rheumatic diseases, Pain in rheumatoid arthritis, Inflammation in rheumatoid arthritis, Degenerative forms of rheumatoid arthritis, Children's rheumatoid arthritis, Exacerbation of rheumatoid arthritis, Acute articular rheumatism, Rheumatic arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatoid arthritis of active course, Rheumatoid arthritis, Rheumatoid polyarthritis, Acute rheumatoid arthritis, Acute rheumatism

M10 Gout

Exacerbation of gout, Acute articular attack with gout, Acute gouty attack, Gouty attack, Recurrent gout attacks, Chronic gout

M13.9 Arthritis, unspecified

Arthritis,Purulent arthritis (non-infectious), acute Arthritis,Pain in acute inflammatory diseases of the musculoskeletal system,Pain in chronic inflammatory diseases of the musculoskeletal system,The pain in osteoarthritis, Inflammation in osteoarthritis, Inflammatory arthropathy, Inflammatory and degenerative joint diseases, Inflammatory disease of the musculoskeletal system, Inflammatory joint disease, Inflammatory diseases of the musculoskeletal system, destructive arthritis, The disease of the musculoskeletal system, Diseases of the musculoskeletal system, Diseases of the musculoskeletal system and connective tissue, Infections musculoskeletal system, monoartrit, Non-infectious arthritis, rheumatic arthritis, Osteoarthritis, Acute inflammation of the musculoskeletal tissue, Acute inflammatory diseases of the musculoskeletal system, Acute inflammatory condition of the musculoskeletal system, Acute arthritis, Acute osteoarthritis, Post-traumatic osteoarthritis, Reactive arthritis, Chronic inflammatory diseases of the joints, Chronic arthritis, Chronic inflammatory arthritis, Chronic inflammation of the inner layer of the joint capsule, Chronic inflammation of the joint capsule,Chronic inflammatory disease of the joints, Exudative arthritis

M15-M19 Osteoarthritis

M32 Systemic lupus erythematosus

Lupus erythematosus red disseminated, Disseminated lupus erythematosus, Chronic lupus erythematosus

M34 Systemic sclerosis

Scleroderma, Scleroderma generalized, Scleroderma diffuse, Scleroderma universal, Sclerosis systemic progressing, Buschke's disease, Sculpting adults, Sclera aponeurotic benign

M35.9 Unspecified systemic involvement of connective tissue

Hyperplasia of connective tissue, Diffuse connective tissue disease, Collagen diseases, Collagenosis, Systemic diseases of connective tissue, Diffuse connective tissue diseases

M45 Ankylosing spondylitis

Ankylosing spondylarthrosis, Marie-Strumpel disease, Ankylosing spondylitis, Pain syndrome in acute inflammatory diseases of the musculoskeletal system, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Bechterew's disease, Ankylosing spondylitis, Diseases of the spinal column, Rheumatic spondylitis, Bechterew-Marie-Strumpel disease

M60 Myositis

Myositis, Fibrositis Fibromyositis, Inflammatory disease of soft tissues

M71 Other bursopathies

Bursitis, Bursopathy, Diseases of soft tissues, Osteoarthritis in musculo-articular diseases, Inflammatory disease of soft tissues, Subacute bursitis

M77.9 Other unspecified

Capsule, Periarthritis, Tendonitis, Tendopathy, Periarthropathy

M79.0 Other unspecified rheumatism

Degenerative rheumatic disease, Degenerative and rheumatic diseases of the tendons, Degenerative rheumatic diseases, Localized forms of rheumatism of soft tissues, Rheumatism, Rheumatism with a pronounced allergic component, Rheumatism of the articular and extraarticular, Rheumatic attack, Rheumatic complaints, Rheumatic diseases, Rheumatic disease of the spine, Relapses of rheumatism, Articular and extra-articular rheumatism, Articular and muscular rheumatism, Articular rheumatism, Articular syndrome with rheumatism, Chronic rheumatic pain, Chronic articular rheumatism, Rheumatoid diseases, Rheumatic diseases of the intervertebral disc

M79.1 Myalgia

Myofascial pain syndromes ,Pain syndrome in musculo-articular diseases, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Pain in the muscles, Tenderness of muscles, Muscular soreness in severe physical exertion, Painful conditions of the musculoskeletal system, Pain in the musculoskeletal system, Pain in the muscles, Pain at rest, Muscle aches, Muscle pain, Musculoskeletal pain, Myalgia, Muscle pain, Muscle pain at rest, Muscle pain, Muscular pain of non-rheumatic origin, Muscle pain of rheumatic origin, Acute muscle pain, Rheumatic pain, Rheumatic pains, Myofascial syndrome, Fibromyalgia

N04 Nephrotic syndrome

Nephrosis, Edema of the kidneys, Nephrotic syndrome, Lipoid nephrosis, Nephrotic syndrome without uremia, Acute nephrotic syndrome, Edematic syndrome of renal genesis, Renal form of diabetes insipidus, Segmental glomerulonephritis, Focal glomerulonephritis, Family Nephrotic Syndromes, Chronic nephrotic proteinuric syndrome, Lipiduria, Jade hereditary, Nephrotic-proteinuric syndrome

R68.8.0 * Inflammatory syndrome

Painful syndrome of inflammatory genesis, Pain syndrome with inflammation of non-rheumatic nature, Pain syndrome with inflammatory lesions of the peripheral nervous system, Painful inflammation of the shoulder joint, Painful inflammation after trauma or surgery, Painful inflammation after surgery, Painful hemorrhoids, Inflammation of the tympanic membrane, Inflammation of the larynx, Inflammation of the gums, Inflammation of cellulose, Inflammation of lymph nodes, Tonsillitis, Inflammation of muscles, Inflammation of soft tissues, Inflammation of the mouth, Inflammation after surgery and trauma, Inflammation after orthopedic surgery, Inflammation after trauma, Inflammation in rheumatoid arthritis, Inflammation of the middle ear, Inflammatory gum disease, Inflammatory diseases of the eyelids, Inflammatory eye diseases, Inflammatory swelling of soft tissues, Inflammatory processes, Inflammatory processes after surgical interventions, Inflammatory process, Inflammatory Syndrome, Inflammatory syndrome of non-rheumatic origin, Inflammatory syndrome after surgery, Purulent infections, Infringements of function of a liver of an inflammatory etiology, Acute inflammation of the musculoskeletal tissue, Pre-inflammatory soft tissue inflammation

T30 Thermal and chemical burns, unspecified

Pain syndrome with burns, Pain in burns, Pain with burns, Sluggishly healing post-burn wounds, Deep burns with a wet scab, Deep burns with abundant compartments, Deep burn, Laser burn, Burn, Burning of the rectum and perineum, Burn with mild exudation, Burn disease, Burn injury, Superficial burn, Superficial burn of I and II degree, Superficial skin burns, After-burn trophic ulcer and wound, Post-burn complication, Loss of fluid during burns, Sepsis burn, Thermal burns, Thermal skin lesions, Thermal burn, Trophic after-burn ulcers, Chemical burn, Surgical burn

T78.2 Anaphylactic shock, unspecified

Anaphylactic shock, Anaphylactoid reaction, Anaphylactic shock, Anaphylactic reactions, Anaphylactic shock to drugs

T78.3 Angioedema

Edema Quincke, Laryngeal exacerbation with angioneurotic edema, Recurrent angioedema, Allergic edema, Recurrent swelling of Quincy

T78.4 Allergy, unspecified

Allergic reactions to insulin, Allergic reactions to insect stings, Allergic reactions similar to systemic lupus erythematosus, Allergic diseases, Allergic diseases of mucous membranes, Allergic diseases and conditions resulting from increased release of histamine, Allergic diseases of mucous membranes, Allergic symptoms, Allergic symptoms in the mucous membranes, Allergic reactions, Allergic reactions caused by insect bites, Allergic reactions, Allergic conditions, Allergic laryngeal edema, allergopathy, allergic conditions, Allergy, House dust allergy, Anaphylaxis, Cutaneous reactions to medications, Skin reaction to insect stings, Cosmetic allergy, Drug allergy, Acute allergic reaction, Laryngeal edema allergic genesis and background radiation, Food and drug allergy

Code CAS124-94-7

Characteristics

White or white with a yellow hue of crystalline powder. Insoluble in water, poorly soluble in alcohol.

Pharmacology

Pharmacological action - anti-inflammatory, antiallergic, immunosuppressive, glucocorticoid.

Activates specific receptors located in the cytoplasm of cells of target organs, induces the synthesis of mRNA and the formation of a special class of proteins - lipocortins, one of which is lipomodulin, inhibits the activity of phospholipase A2. Regulates all types of metabolism, has anti-anabolic and catabolic effects. Reduces the utilization of glucose by insulin-dependent tissues, causes hyperglycemia, increases the amount of glycogen in the liver (activates gluconeogenesis), enhances the breakdown of fats, delays sodium and water ions, promotes the excretion of potassium ions, reduces the absorption of calcium ions, induces the secretion of parathyroid hormone that mobilizes calcium from bone tissue. Anti-inflammatory properties are due to the stabilization of cell membranes, incl. (Lysosomes), inhibition of phospholipase A2 activity (lipomodulin), cessation of arachidonic acid liberation from phospholipids of cell membranes and a decrease in the level of its metabolic products (PG (prostaglandins), Tx, leukotrienes). It inhibits hyaluronidase, prevents splitting of the main substance of the connective tissue, inhibits the division of mast cells and reduces their degranulation (with the release of histamine, serotonin, bradykinin), suppresses the synthesis of platelet activation factor and proliferation of connective tissue. Reduces the number of T- and B-lymphocytes, disturbs their interaction, stops the migration of B-lymphocytes (immunosuppressive and anti-allergic action). Reduces the concentration of immunoglobulins in the serum, inhibits the cooperation of phagocytes and lymphocytes. Anti-shock and antitoxic action is associated with increased blood pressure (due to an increase in the concentration of circulating catecholamines and restoration of sensitivity to adrenoreceptors, as well as vasoconstriction), a decrease in the permeability of the vascular wall, membrane-protective properties, activation of liver enzymes involved in the metabolism of endo- and xenobiotics . Increases the excitability of the central nervous system (CNS), reduces the number of lymphocytes and eosinophils, increases erythrocytes (stimulates the production of erythropoietins).

After oral administration, 20-30% is absorbed. In plasma, 40% binds to proteins. T1 / 2 (tablet form) is 5 hours. It is subject to biotransformation in the liver with the formation of inactive metabolites. T1 / 2 in tissues - 18-36 hours Excreted mainly by the kidneys in an inactive form.

After oral administration, the maximum effect is observed after 1-2 hours, IM after 24-48 hours. The duration of action depends on the mode of administration and is 2.5 days (orally), 1-6 weeks (IM) or several weeks (Into the joint cavity).

Application of Triamcinolone

Adrenal insufficiency, autoimmune thyroiditis, hypercalcemia in malignant neoplasms, psoriatic arthritis, gouty and rheumatoid arthritis (including juvenile), ankylosing spondylitis, bursitis, tendovaginitis, posttraumatic osteoarthritis, epicondylitis, systemic lupus erythematosus, rheumatic carditis, pemphigus, Stevens-Johnson syndrome, erythema multiforme , Dermatitis (exfoliative, herpetiform, bullous, seborrheic, contact, atonic), psoriasis, allergic rhinitis, bronchial asthma, whey Or an allergic conjunctivitis, keratitis, iridocyclitis, sarcoidosis, Loeffler syndrome, borreliosis, aspiration pneumonia, idiopathic thrombocytopenic purpura of adults, secondary thrombocytopenia of adults, anemia (autoimmune hemolytic, hereditary hypoplastic), erythroblastopenia, acute or chronic lymphoblastic leukemia, lymphogranulomatosis, Non-Hodgkin's lymphomas, breast cancer, prostate cancer, myeloma, tuberculous meningitis, acute lymphocytic leukemia in children, nave otic syndrome, ulcerative colitis, Crohn's disease, celiac disease, hyperthermia for malignant tumors.

Contraindications

Hypersensitivity, systemic mycoses, glaucoma, peptic ulcer of the stomach and duodenum, impaired renal function, osteoporosis, acute viral and bacterial infections, pregnancy, breast-feeding, children under 6 years.

Side effects

Insomnia, anxiety, withdrawal syndrome (adrenal insufficiency), secondary immunodeficiency (exacerbation of chronic infectious diseases, generalization of the infectious process, development of opportunistic infections), slowing of reparative processes, steroid diabetes, Itzenko-Cushing syndrome, arterial hypertension, myocardial dystrophy, cardiac arrhythmias, Edema, muscle weakness, muscle atrophy, osteoporosis, multiple caries, spontaneous fractures, growth retardation in children, steroid stomach ulcers, atony intestines Linda, the tendency to thrombosis, atrophy of the skin at the site of application, hypertrichosis, striae, folliculitis, maceration, or skin dryness, allergic reactions.

Interaction

Reduces the effectiveness of oral hypoglycemic agents, insulin, hypotensive and diuretics, somatotropin. When combined with viral vaccines, replicates viral particles and / or reduces antibody production. Increases the side effects of NSAIDs (nonsteroidal anti-inflammatory drugs), cytostatics and immunosuppressants.

Overdose

Symptoms: Itenko-Cushing syndrome, hyperglycemia, glucosuria, skin irritation at the site of application, itching, burning.

Treatment: maintenance of vital functions (against a background of gradual withdrawal of the drug).

Routes of administration

Inside, in / m (intramuscularly), into the joint cavity or into the vagina of the tendon.

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