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Instruction for use: Rabivac-Vnukovo-32 Vaccine anti-rabies culture inactivated for human immunization

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Dosage form: lyophilisates for solution for intramuscular and subcutaneous administration

ATX

J07BG01 Inactivated whole rabies virus

Pharmacological group:

Vaccines, serums, phages and toxoids

The nosological classification (ICD-10)

A82 Rabies: Rabies; Suspicion for rabies; Hydrophobia (hydrophobia)

Composition and release form

Inactivated vaccine for the prevention of rabies (strain Vnukovo-32, grown in the primary culture of kidney cells of Syrian hamsters), immunogenic activity of at least 0.5 IU / ml. Stabilizers: gelatin - at a final concentration of up to 1%, sucrose at a final concentration of up to 7.5%, albumin at a final concentration of 0.5%; Preservative - kanamycin monosulfate (150 μg / ml). Powder for the preparation of an injection solution in ampoules of 3 ml complete with a solvent (distilled water) in ampoules of 3 ml, in a package of 5 sets.

Pharmachologic effect

Mode of action - Immunostimulating.

Forms immunity to the rabies virus.

Indication of the drug Rabivac-Vnukovo-32 Vaccine anti-rabies culture inactivated for human immunization

Rabies (preventive and preventive immunization).

Contraindications

For treatment and prophylactic immunization, conducted according to vital indications, there are no contraindications. For preventive immunization: hypersensitivity, acute infectious and general diseases, congestive heart failure, chronic kidney and endocrine system diseases, collagenoses, bronchial asthma, pregnancy, lactation.

Side effects

Edema at the injection site, redness, itching, an increase in regional lymph nodes, malaise, headache, nausea, a slight increase in temperature.

Dosing and Administration

SC, in the stomach tissue is injected immediately after dissolution (the dissolved vaccine is not to be stored), in exceptional cases the vaccine can be injected into the subcutaneous tissue of the interblade area). Dosage and immunization schedule depend on the indications.

Precaution measures

After the introduction, it is necessary to observe the vaccinated for 30 minutes (the possibility of developing allergic reactions). The preparation is not suitable for use in ampoules with broken integrity and marking, with changing physical properties (turbidity, intense staining, presence of non-breakable flakes), expired shelf life, improper storage.

Storage conditions of the drug Rabivac-Vnukovo-32 Vaccine anti-rabies culture inactivated for human immunization

At a temperature of 2-8 ° C.

Keep out of the reach of children.

Shelf life of the drug Rabivac-Vnukovo-32 Vaccine anti-rabies culture inactivated for human immunization

1,5 years.

Do not use after the expiry date printed on the package.

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