Instructions / Instruction for use: Norethisterone (Norethisteronum)I want this, give me price
Estrogens, gestagens; Their homologues and antagonists
Nosological classification (ICD-10)
D26 Other benign neoplasms of the uterus
Fibromyoma of the uterus, Myoma, Uterine fibroids, Fibromyoma, Myoma of the uterus, Fibrrios, Meigs syndrome, Tumors of the uterus
Mastalgia, Soreness of the mammary glands, Cooper's disease
N64.9 Mammary disease, unspecified
Mastopathy, Neoplastic processes in the mammary gland
N80.0 Endometriosis of the uterus
Adenomyosis, Endometrioid endometriosis
N85.0 Endometrial glandular hyperplasia
Hyperplastic processes of the endometrium, Cystic glandular hyperplasia of the endometrium
N93.9 Abnormal uterine and vaginal bleeding, unspecified
Uterine bleeding, Dysfunctional uterine bleeding, Uterine bleeding dysfunctional
N94.3 Premenstrual tension syndrome
Pronounced premenstrual syndrome, Menstrual psychosomatic disorder, Menstrual syndrome, Premenstrual tension, Premenstrual status, Premenstrual period, Premenstrual syndrome, Menstruation syndrome
N94.4 Primary dysmenorrhea
Primary functional dysmenorrhea, Pain in primary dysmenorrhea, Primary algodismenorea, Menstrual cramps
N94.5 Secondary dysmenorrhea
Dysmenorrhea secondary acquired, Menstrual cramps, Ovarian depletion syndrome
N94.6 Dysmenorrhea Unspecified
Pain during menstruation, Functional disorders of the menstrual cycle, Menstrual cramps, Emmeniopathy, Pain during menstruation, Painful menstrual irregularities, algomenorrhea, algomenoreya, Pain smooth muscle spasm, Pain spasm of smooth muscles (renal and biliary colic, intestinal spasms, dysmenorrhea), Pain spasm of smooth muscles of internal organs (kidney and biliary colic, intestinal spasms, dysmenorrhea), Disalgomenoreya, dysmenorrhea, Dysmenorrhea (essential) (Exfoliative), menstrual disorder, menstruation painful, metrorrhagia, Violation of the menstrual cycle, Menstrual irregularities, Prolaktinzavisimoe menstrual disorders, Prolaktinzavisimoe menstrual dysfunction, Pain spasm of smooth muscles of internal organs, Spasmodic dysmenorrhea, Primary disalgomenoreya
N95.9 Menopausal and perimenopausal disorders, unspecified
Postmenopause, Atrophy of the vulva, Climacteric syndrome, Postmenopausal period, Premenopausal period, Menopausal Symptom
N97 Female infertility
Female infertility in anovulation, Hyperprolactinemic infertility, Hyperprolactinaemia with infertility, Endocrine infertility, Infertility due to hypothalamic-pituitary dysfunction, Infertility infertility, Infertility, Infertility on the background of hyperprolactinaemia, Functional infertility, Marriage is infertile, Infertility of ovarian genesis, Stimulation of the growth of a single follicle
O26.2 Medical care for a woman with habitual miscarriage
Miscarriage habitual, Unintention of pregnancy, Habitual miscarriage of pregnancy, Psychological problems with miscarriage
Z30.0 General advice and advice on contraception
Safe sex, Intrauterine device contraception, Contraception, Contraceptive intrauterine, Oral contraception, Oral contraception during lactation and with estrogen contraindications, Postcoital contraception, Prevention of Pregnancy, Prevention of unwanted pregnancy, Emergency Contraception, Episodic prevention of pregnancy, Contraception in adolescents, Prevention of pregnancy (contraception)
The pharmacological action is gestagenic.
Inhibits the proliferative activity in hyperplastic endometrium, promotes secretory transformation reactions development of decidual stroma and atrophic changes of epithelial glands and stroma. Oppresses the secretion of gonadotropic hormones by the pituitary gland.
Well absorbed when taken orally. The time to reach Cmax is about 2 hours. In the liver, with the participation of enzymes of microsomal oxidation, biotransformation is exposed. T1 / 2 - 3-10 hours Excreted in the urine (up to 70% of the administered dose) and the intestine.
Application of Norethisterone
Premenstrual syndrome, mastodynia, mastopathy, dysmenorrhea with shortening secretory phase, dysfunctional uterine bleeding (with substitution purposes in failure corpus luteum hormone), tuberculosis, primary and secondary amenorrhea, cystic glandular hyperplasia of the endometrium, endometriosis, adenomyosis, uterine fibroids, infertility, miscarriage , Prevention and cessation of lactation, postponement of another menstruation, climacteric syndrome, contraception.
Hypersensitivity, breast cancer (including suspected) and sexual organs, the tendency to thrombosis, acute thrombophlebitis or thromboembolism, urinary tract bleeding of unknown origin, metrorrhagia unclear origin, bleeding from genitals of unclear origin, cholestatic jaundice of pregnant women (in m .ch. history), acute liver disease (including benign and malignant neoplasms) expressed hepatic dysfunction, hepatitis, cirrhosis, pregnancy (including suspected it, except Application for miscarriage), the period of puberty.
Restrictions for use
Bronchial asthma, chronic heart failure, epilepsy, hypertension, migraine, renal failure, convulsions, impaired central nervous system (including history), diabetes mellitus, liver disease (disorder), hyperlipidemia, thrombophlebitis a history of thromboembolism in Anamnesis.
Nausea, vomiting, metrorrhagia, peripheral edema, fatigue, paresthesias, weight gain, breast tenderness, allergic reactions (rash, pruritus); With prolonged use - thrombosis, thromboembolism.
Barbiturates reduce plasma concentrations (accelerate metabolism).
Routes of administration
Before the beginning of treatment it is necessary to clarify the cause of vaginal bleeding, confirm its functional character and exclude the presence of malignant neoplasm.