Instruction for use: Kalium iodid 200 Berlin-Chemie

ATX Code H03CA Potassium Jodid

Active substance Potassium Jodid

Pharmacological group

Inorganic iodine preparation [Thyroid and parathyroid hormones, their analogs and antagonists (including antithyroid agents) / 67 /]

Macro and microelements

Nosological classification (ICD-10)

E01 Thyroid gland diseases associated with iodine deficiency and similar conditions

Hormonal deficiency of the thyroid gland due to iodine deficiency in the body, Goiter endemic, Iodine deficiency alimentary state, Iodine deficiency disease, Iodine Deficiency, Endemic cretinism

Composition and form of release

1 tablet contains potassium iodide 262 μg, which corresponds to 200 μg of iodide; In a blister of 25 pcs., In a box of 2 or 4 blisters.

pharmachologic effect

Pharmacological action - filling iodine deficiency.

By the type of feedback inhibits the synthesis and the release of thyroid-stimulating hormone, which stops the growth of goiter, normalizes the production of thyroid hormones, which is disturbed by the lack of iodine.

Pharmacodynamics

After absorption from the gastrointestinal tract enters the blood, from the blood is absorbed by the thyroid gland, where it is oxidized to iodine, which is used for iodination of tyrosine and its conversion into mono-and diiodotyrosine (thyroid hormone precursors).

Indications

Prevention of the development of diseases caused by iodine deficiency (prevention of goiter in areas with iodine deficiency, pregnancy, adolescence, etc.); Treatment of goiter and other iodine deficiency diseases in children (including newborns and adolescents) and adults (young age).

Contraindications

Hypersensitivity to iodine, expressed and hidden (for doses exceeding 150 micrograms of iodine per day), hyperthyroidism, benign tumors, etc. focal and diffuse autonomy of the thyroid gland, especially in old age (for doses of 300-1000 μg / day); Herpetiform (senile) dermatitis of Dühring.

pregnancy and lactation

During pregnancy and lactation, application in preventive doses (in iodine-deficient regions) is especially recommended.

Side effects

Hyperfunction of the thyroid gland (when using daily doses above 150 mcg - for the prevention of goiter in the presence of thyroid gland sections with uncontrolled internal secretion of hormones, especially the elderly, or doses above 300-1000 mcg - for treating goiter in adults), the phenomenon of iodine (fever , Acne, swelling of the salivary glands), an increase in the potassium content in the blood (including with limited renal function and simultaneous intake of potassium-sparing diuretics), allergic reactions.

Interaction

The effect is weakened by antithyroid drugs. With simultaneous use with potassium-sparing diuretics, the risk of developing hyperkalemia increases.

Dosing and Administration

Inside, after eating, with liquid. For the prevention of goiter: Adults and adolescent children - 100-200 mg / day; At pregnancy and feeding by a breast - on 150-200 mkg / sut; Children under 12 years of age - 50-100 mcg / day; The same dose is recommended for further treatment after the end of goitre therapy with levothyroxine; Prevention is carried out for several years, sometimes - throughout life.

For treatment of goiter: adults and children of adolescence - up to 300-500 mcg / day; Children under 12 years - up to 100-200 mcg / day; The course of treatment - 6-12 months or more (according to the decision of the attending physician).

Storage conditions

Keep out of the reach of children.

Shelf life

3 years.

Do not use after the expiry date printed on the package.