Instruction for use: Egilok Retard

Trade name of the drug – Egilok Retard

Dosage Form: tablets

Active substance:Metoprololum

ATX

C07AB02 Metoprolol

Pharmacotherapeutic group: Beta1-selective blocker [Beta-blockers]

The nosological classification (ICD-10)

E05 Thyrotoxicosis [hyperthyroidism]: Von Basedow's disease; Basedow's disease; hyperthyroidism; Goitre diffuse toxic; Increased thyroid function; tireotoksicski reaction; Toxic diffuse goiter; goiter; Enlargement of the thyroid gland with symptoms of hyperthyroidism; The phenomenon of iodine Basedow

G43 Migraine: The pain of migraine; Migraine; hemiplegic migraine; Migraine headache; A migraine attack; Continuous headache; hemicrania

I10 Essential (primary) hypertension: hypertension; Arterial hypertension; Arterial hypertension crisis course; Essential Hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Primary hypertension; Arterial hypertension, complications of diabetes; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; arterial Hypertension; malignant Hypertension; Hypertonic disease; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; Isolated systolic hypertension

I15 Secondary hypertension: Arterial hypertension, complications of diabetes; hypertension; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; hypertension; arterial Hypertension; malignant Hypertension; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; hypertension; Arterial hypertension; Arterial hypertension crisis course; renovascular hypertension; Hypertension symptomatic; Renal hypertension; Renovascular hypertension; renovascular hypertension; Symptomatic hypertension

I20 Angina [angina]: Heberden disease; Angina pectoris; The attack of angina pectoris; recurrent angina; Spontaneous angina; Stable angina pectoris; Angina rest; Angina progressing; Angina mixed; Angina spontaneous; stable angina; Chronic stable angina; Angina Syndrome X

I25.2 Transferred last myocardial infarction: Cardiac syndrome; Myocardial infarction; post-MI; Rehabilitation after myocardial infarction; Reocclusion of the operated vessel; Angina postinfarctnaya; Status after myocardial infarction; Status after myocardial infarction; myocardial infarction

I25.9 Chronic ischemic heart disease, unspecified: CHD; Insufficiency of coronary circulation; Coronary atherosclerosis in patients with coronary artery disease

I47.1 Supraventricular tachycardia: Supraventricular paroxysmal tachycardia; supraventricular tachyarrhythmia; supraventricular tachycardia; Supraventricular arrhythmias; Supraventricular paroxysmal tachycardia; supraventricular tachyarrhythmias; supraventricular tachycardia; Neurogenic sinus tachycardia; orthodromic tachycardia; Paroxysmal supraventricular tachycardia; Paroxysm of supraventricular tachycardia; Paroxysm of supraventricular tachycardia with WPW-syndrome; Paroxysm of atrial tachycardia; Paroxysmal supraventricular tachyarrhythmia; Paroxysmal supraventricular tachycardia; Politopnye atrial tachycardia; Atrial fibrillation; Atrial tachycardia is true; Atrial tachycardia; Atrial tachycardia with AV block; reperfusion arrhythmias; Reflex Bertsolda-Jarisch; Recurrent sustained supraventricular paroxysmal tachycardia; Symptomatic ventricular tachycardia; Sinus tachycardia; Supraventricular paroxysmal tachycardia; supraventricular tachyarrhythmia; supraventricular tachycardia; supraventricular arrhythmia; supraventricular arrhythmias; Tachycardia of AV connections; supraventricular tachycardia; Tachycardia orthodromic; sinus tachycardia; The nodal tachycardia; Chaotic atrial tachycardia politopnye; Wolff-Parkinson-White

I49.3 Premature ventricular depolarization: Asynergia left ventricle; ventricular Arrhythmia; Pronounced PVCs; fibrillation; ventricular beat; ventricular beat; Ventricular arrhythmias; ventricular beat; Paroxysmal ventricular arrythmia; Recurrent ventricular arrhythmias; ventricular premature beats; Asynergia ventricular

I50.0 Congestive heart failure: anasarca heart; Decompensated congestive heart failure; Congestive heart failure; Congestive heart failure with high afterload; Congestive chronic heart failure; Cardiomyopathy with severe chronic heart failure; Compensated chronic heart failure; Swelling with circulatory failure; Edema of cardiac origin; Swelling of the heart; Edematous syndrome in diseases of the heart; Edematous syndrome in congestive heart failure; Edematous syndrome in heart failure; Edematous syndrome in heart failure or liver cirrhosis; right ventricular failure; Congestive Heart Failure; Heart failure stagnant; Heart failure with low cardiac output; Heart failure is a chronic; Cardiac edema; Chronic decompensated heart failure; Chronic Congestive Heart Failure; Chronic heart failure; Change of liver function in heart failure

I51 Complications and ill-defined heart disease: cardiac hyperkinetic syndrome

R00.0 Unspecified Tachycardia: Tachycardia

Composition (per tablet): active substance: metoprolol tartrate 50 mg, 100 mg

Other ingredients: colloidal anhydrous silica - 1,088 / 2,175 mg; magnesium stearate - 1,088 / 2,175 mg; MCC - 58.5 / 117 mg

pellets: macrogol 6000 - 5/10 mg; Sweet semolina (sucrose, starch syrup) - 6.23 / 12.45 mg; talc - 5/10 mg

pellet shell: giproloza - 3.5 / 7 mg; magnesium stearate - 3.7 / 7.4 mg; triethylcitrate - 2.65 / 5.3 mg of ethyl cellulose - 13.25 / 26.5 mg

shell film: Valium - 5/10 mg; Macrogol 6000 - 1.2 mg; Talc - 2.1 mg; titanium dioxide (E171) - 3/6 mg

Pharmacological Properties of Egilok Retard

Pharmachologic effect - antianginal, hypotensive, anti-arrhythmic.

Dosage and Administration

The inside is not liquid, squeezed liquid. Take one tablet every day in the morning. The tablets can be taken without food. If necessary, the tablet can break in half. In order to prevent bradycardia dose picked individually and increase gradually.

Arterial hypertension. The recommended starting dose is 50 mg 1 time a day. When insufficient therapeutic effect daily dose can be increased to 100 or 200 mg, or add another antihypertensive agent. The maximum daily dose - 200 mg.

Angina. The recommended starting dose for angina is 50 mg 1 time a day. When insufficient therapeutic effect daily dose can be increased to 100 or 200 mg, or add other antianginal agent.

Secondary prevention of myocardial infarction. Usual maintenance dose - 200 mg 1 time per day.

Heart failure compensation stage. The recommended initial dose - 25 mg 1 time a day. After 2 weeks the daily dose can be increased to 50 mg after 2 weeks - 100 mg, and finally, after another two weeks - 200 mg.

Arrhythmias. The usual dose is 50-200 mg 1 time a day.

Hyperthyroidism. The usual dose is 50-200 mg 1 time a day.

Functional heart disorders accompanied by tachycardia. The usual dose is 50-200 mg 1 time a day.

Prophylaxis of migraine attacks. 100-200 mg 1 time per day.

Elderly patients with renal insufficiency or in patients on hemodialysis, the dose adjustment is required.

Violations of the liver affect the elimination of metoprolol, and therefore with severe hepatic impairment should be reduced dose according to the patient's clinical condition.

Release Form

The long-acting tablets, film-coated, 50 mg and 100 mg. According to Table 10. a polypropylene blister film and aluminum foil. 1, 2 or 3 blisters in a carton box.

Manufacturer

Atsino Pharma AG, Switzerland.

Registration Certificate Holder: CJSC "Pharmaceutical plant EGIS." 1106 Budapest, ul. Keresturi, 30-38, Hungary.

Claims sent to representative of JSC "Pharmaceutical plant EGIS" (Hungary) in Moscow. 121108, Moscow, ul. Ivan Franko, 8.

Conditions of supply of pharmacies

On prescription.

Storage conditions of Egilok Retard

The temperature is not above 30 ° C.

Keep out of the reach of children.

Shelf life

5 years.

Do not use beyond the expiration date printed on the package.