Instruction for use: Anatoxinum diphthericum purificatum adsorptum cum quantitate minore antigenori fluidum

Dosage form: Suspension for intramuscular and subcutaneous administration; Suspension for injections

Active substance: Anatoxinum diphtericum

ATX

J06AA01 Diphtheria toxoid

Pharmacological group:

Vaccines, serums, phages and toxoids

The nosological classification (ICD-10)

A36.9 Diphtheria, unspecified

Composition and release form

One inoculation dose (0.5 ml) of the vaccine contains 5 flocculating units (LF) of diphtheria toxoid. Sorbent - aluminum hydroxide (0.25-0.55 mg / ml), preservative - mertiolate (0.05 mg / ml). Ampoules of 1 ml (two inoculations), in the package 10 pcs.

Characteristic

AD-M-anatoxin with a reduced antigen content consists of diphtheria toxoid sorbed on aluminum hydroxide. The preparation is a suspension of white or slightly yellowish color, separated when standing on a clear liquid part and a loose sediment, completely shattered by shaking.

Pharmachologic effect

Mode of action - Immunostimulating.

Forms immunity against diphtheria.

Indication of the drug Anatoxinum diphthericum purificatum adsorptum cum quantitate minore antigenori fluidum

Diphtheria (prevention).

Contraindications

Acute infectious diseases (no earlier than 2-4 weeks after recovery), exacerbation of chronic diseases, pregnancy.

Side effects

Rarely: fever, weakness, tenderness in the place of inoculation, hyperemia, puffiness, allergic reactions and exacerbation of allergic diseases.

Dosing and Administration

IM in the upper outer quadrant of the buttocks or anteroar portion of the femur or sciatica in the scapular region in a single dose of 0.5 ml. Before vaccination, the ampoule must be shaken thoroughly until a homogeneous suspension is obtained. The full course of immunization consists of two vaccinations with an interval of 30-45 days and subsequent revaccination after 6-9 months. Regular revaccinations in 10 years.

Precaution measures

Given the possibility of developing allergic reactions of immediate type, the patient should be monitored within 30 minutes after administration. Preparations should be made for anti-shock therapy. The preparation is not suitable for use in ampoules with broken integrity and lack of marking, with changing physical properties (color, presence of non-breaking flakes), expired shelf life, improper storage.

Storage conditions of the drug Anatoxinum diphthericum purificatum adsorptum cum quantitate minore antigenori fluidum

In the dry, dark place at a temperature of 4-8 ° C.

Keep out of the reach of children.

Shelf life of the drug Anatoxinum diphthericum purificatum adsorptum cum quantitate minore antigenori fluidum

3 years.

Do not use after the expiry date printed on the package.