Phenotropil is a nootropic preparation. The active substance is N-carbamoyl-methyl-4-phenyl-2-pyrrolidone. The drug has the ability to directly improve the integrative function of the brain. This leads to an improvement in mental abilities, learning ability, memory consolidation, improvement of attention. In addition, Phenotropil has an anticonvulsant effect, anxiolytic properties, improves mood, normalizes the processes of inhibition and excitation in the brain, has an anorexigenic effect. With the course of application, phenotropin improves the stability of brain tissue in conditions of hypoxia. Due to the neuroprotective properties of Phenotropil, indications for its use include pathology caused by the influence of toxic substances, hypoxia. The drug improves the blood supply to the brain, stimulates metabolic processes in neurons.
Fenotropil has the ability to increase regional blood flow during hypoxia. Improving the energy potential of neurons is provided by enhanced utilization of glucose. Phenotropil does not affect the CAS and respiratory system. It is noted that with the course of taking Fenotropil the visual acuity improves, the perception of the brightness of the flowers increases.
The drug Fenotropil has adaptogenic properties (increases resistance to a stressful situation), which is especially evident with significant emotional and physical exertion. Phenotropil moderately affects motor reactions, reduces the inhibitory effect of ethanol and hexenal on brain tissue. It is an antagonist of the cataleptic effect of neuroleptics. Fenotropil has some analgesic effect due to an increase in the threshold of pain sensitivity.
Also, this drug improves blood flow in the vessels of the lower extremities. The positive properties of phenothropil include the absence of teratogenic, carcinogenic, mutagenic, embryotoxic effects and low toxicity. With the course of this drug, there were no symptoms of withdrawal syndrome, which reinforces the positive feedback about phenothyrope. In addition, tolerance and drug dependence do not develop.
Fentropil is a patented preparation. There is no analogue of Fentropil for the time being. When taken orally, the drug is rapidly absorbed into the digestive tract, it penetrates the blood-brain barrier. The maximum concentration is achieved one hour after administration. It is not metabolized in the body. Half-life is 3-5 hours. 60% of the drug is excreted with sweat and bile, 40% - with urine. Characterized by 100% bioavailability of Phenotropil.
Indications for use of Fenotropil
In the instructions for Fenotropil, indications are indicated for the purpose: neurotic states characterized by worsening of psycho-vascular activity, excessive fatigue, lethargy, memory loss, cognitive impairment; depressive conditions; pathology of the central nervous system associated with impaired metabolism in the brain and blood supply, as well as other diseases, accompanied by a violation of the intellectual-mnestic function; convulsive diseases; the need to invert the sleep-wakefulness regime (in connection with professional activities); alimentary-constitutional obesity; schizophrenia (vyaloapaticheskoe current); with a preventive purpose in case of stressful situations, extreme influences of professional activity, hypoxia, for stimulation of mental and physical working capacity; chronic alcoholism (to reduce asthenia, depression, enhance intellectual and mnestic functions); psychoorganic syndrome with the phenomena of lethargy, apathy, abulian disorders.
Phenotropil Dosage and Administration
Phenotropil is intended for oral administration. The tablet should be taken after a meal. The dosage of the drug, as well as the duration of therapy, is determined by the doctor depending on the clinical situation. The average dosage of Phenotropil for one dose is 100-250 mg. The maximum daily dosage is 750 mg. The daily dosage should be divided into two doses. If the daily dosage is 100 mg, let us take a single dose per day. The average duration of treatment is a month. With alimentary-constitutional obesity, Phenotropil is used for 100-200 mg for one to two months.
Tablets Fenotropil It is advisable to take Phenotropil no later than 15:00.